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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TAF5L
Full Name:
TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L
Alias:
PCAF-associated factor 65 beta
Type:
Mass (Da):
66155
Number AA:
589
UniProt ID:
O75529
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y16
I
Q
M
A
V
S
C
Y
L
K
R
R
Q
Y
V
Site 2
Y22
C
Y
L
K
R
R
Q
Y
V
D
S
D
G
P
L
Site 3
S25
K
R
R
Q
Y
V
D
S
D
G
P
L
K
Q
G
Site 4
S36
L
K
Q
G
L
R
L
S
Q
T
A
E
E
M
A
Site 5
T47
E
E
M
A
A
N
L
T
V
Q
S
E
S
G
C
Site 6
Y70
C
Q
A
E
P
Q
Q
Y
E
V
Q
F
G
R
L
Site 7
T82
G
R
L
R
N
F
L
T
D
S
D
S
Q
H
S
Site 8
S84
L
R
N
F
L
T
D
S
D
S
Q
H
S
H
E
Site 9
S86
N
F
L
T
D
S
D
S
Q
H
S
H
E
V
M
Site 10
S111
H
L
N
L
V
Q
N
S
P
K
S
T
V
E
S
Site 11
S114
L
V
Q
N
S
P
K
S
T
V
E
S
F
Y
S
Site 12
T115
V
Q
N
S
P
K
S
T
V
E
S
F
Y
S
R
Site 13
S118
S
P
K
S
T
V
E
S
F
Y
S
R
F
H
G
Site 14
Y120
K
S
T
V
E
S
F
Y
S
R
F
H
G
M
F
Site 15
S121
S
T
V
E
S
F
Y
S
R
F
H
G
M
F
L
Site 16
S132
G
M
F
L
Q
N
A
S
Q
K
D
V
I
E
Q
Site 17
T142
D
V
I
E
Q
L
Q
T
T
Q
T
I
Q
D
I
Site 18
T145
E
Q
L
Q
T
T
Q
T
I
Q
D
I
L
S
N
Site 19
S151
Q
T
I
Q
D
I
L
S
N
F
K
L
R
A
F
Site 20
Y163
R
A
F
L
D
N
K
Y
V
V
R
L
Q
E
D
Site 21
S171
V
V
R
L
Q
E
D
S
Y
N
Y
L
I
R
Y
Site 22
Y172
V
R
L
Q
E
D
S
Y
N
Y
L
I
R
Y
L
Site 23
Y174
L
Q
E
D
S
Y
N
Y
L
I
R
Y
L
Q
S
Site 24
Y178
S
Y
N
Y
L
I
R
Y
L
Q
S
D
N
N
T
Site 25
T185
Y
L
Q
S
D
N
N
T
A
L
C
K
V
L
T
Site 26
Y207
Q
P
A
K
R
T
D
Y
Q
L
Y
A
S
G
S
Site 27
Y210
K
R
T
D
Y
Q
L
Y
A
S
G
S
S
S
R
Site 28
S212
T
D
Y
Q
L
Y
A
S
G
S
S
S
R
S
E
Site 29
S214
Y
Q
L
Y
A
S
G
S
S
S
R
S
E
N
N
Site 30
S215
Q
L
Y
A
S
G
S
S
S
R
S
E
N
N
G
Site 31
S216
L
Y
A
S
G
S
S
S
R
S
E
N
N
G
L
Site 32
S218
A
S
G
S
S
S
R
S
E
N
N
G
L
E
P
Site 33
S230
L
E
P
P
D
M
P
S
P
I
L
Q
N
E
A
Site 34
S255
R
V
K
D
G
P
P
S
L
T
T
I
C
F
Y
Site 35
T273
N
T
E
Q
L
L
N
T
A
E
I
S
P
D
S
Site 36
S296
N
S
C
I
K
L
W
S
L
R
S
K
K
L
K
Site 37
S299
I
K
L
W
S
L
R
S
K
K
L
K
S
E
P
Site 38
S304
L
R
S
K
K
L
K
S
E
P
H
Q
V
D
V
Site 39
Y346
R
G
H
C
G
P
V
Y
S
T
R
F
L
A
D
Site 40
S347
G
H
C
G
P
V
Y
S
T
R
F
L
A
D
S
Site 41
S355
T
R
F
L
A
D
S
S
G
L
L
S
C
S
E
Site 42
S359
A
D
S
S
G
L
L
S
C
S
E
D
M
S
I
Site 43
S361
S
S
G
L
L
S
C
S
E
D
M
S
I
R
Y
Site 44
Y368
S
E
D
M
S
I
R
Y
W
D
L
G
S
F
T
Site 45
T377
D
L
G
S
F
T
N
T
V
L
Y
Q
G
H
A
Site 46
Y380
S
F
T
N
T
V
L
Y
Q
G
H
A
Y
P
V
Site 47
Y395
W
D
L
D
I
S
P
Y
S
L
Y
F
A
S
G
Site 48
S396
D
L
D
I
S
P
Y
S
L
Y
F
A
S
G
S
Site 49
Y398
D
I
S
P
Y
S
L
Y
F
A
S
G
S
H
D
Site 50
S403
S
L
Y
F
A
S
G
S
H
D
R
T
A
R
L
Site 51
T407
A
S
G
S
H
D
R
T
A
R
L
W
S
F
D
Site 52
S412
D
R
T
A
R
L
W
S
F
D
R
T
Y
P
L
Site 53
T416
R
L
W
S
F
D
R
T
Y
P
L
R
I
Y
A
Site 54
Y417
L
W
S
F
D
R
T
Y
P
L
R
I
Y
A
G
Site 55
Y422
R
T
Y
P
L
R
I
Y
A
G
H
L
A
D
V
Site 56
Y440
K
F
H
P
N
S
N
Y
L
A
T
G
S
T
D
Site 57
T443
P
N
S
N
Y
L
A
T
G
S
T
D
K
T
V
Site 58
T449
A
T
G
S
T
D
K
T
V
R
L
W
S
A
Q
Site 59
S454
D
K
T
V
R
L
W
S
A
Q
Q
G
N
S
V
Site 60
S460
W
S
A
Q
Q
G
N
S
V
R
L
F
T
G
H
Site 61
T465
G
N
S
V
R
L
F
T
G
H
R
G
P
V
L
Site 62
S473
G
H
R
G
P
V
L
S
L
A
F
S
P
N
G
Site 63
S477
P
V
L
S
L
A
F
S
P
N
G
K
Y
L
A
Site 64
Y482
A
F
S
P
N
G
K
Y
L
A
S
A
G
E
D
Site 65
T501
L
W
D
L
A
S
G
T
L
Y
K
E
L
R
G
Site 66
Y503
D
L
A
S
G
T
L
Y
K
E
L
R
G
H
T
Site 67
T510
Y
K
E
L
R
G
H
T
D
N
I
T
S
L
T
Site 68
T514
R
G
H
T
D
N
I
T
S
L
T
F
S
P
D
Site 69
S515
G
H
T
D
N
I
T
S
L
T
F
S
P
D
S
Site 70
T517
T
D
N
I
T
S
L
T
F
S
P
D
S
G
L
Site 71
S527
P
D
S
G
L
I
A
S
A
S
M
D
N
S
V
Site 72
S533
A
S
A
S
M
D
N
S
V
R
V
W
D
I
R
Site 73
Y543
V
W
D
I
R
N
T
Y
C
S
A
P
A
D
G
Site 74
S545
D
I
R
N
T
Y
C
S
A
P
A
D
G
S
S
Site 75
S552
S
A
P
A
D
G
S
S
S
E
L
V
G
V
Y
Site 76
S553
A
P
A
D
G
S
S
S
E
L
V
G
V
Y
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation