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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CSDE1
Full Name:
Cold shock domain-containing protein E1
Alias:
Cold shock domain containing E1, RNA-binding; Cold shock domain-containing E1; D1S155E; N-ras upstream gene; NRAS-related gene; NRU; UNR; Upstream of NRAS
Type:
Adaptor/scaffold
Mass (Da):
88885
Number AA:
798
UniProt ID:
O75534
International Prot ID:
IPI00470891
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0003723
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0008584
GO:0006355
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S2
_
_
_
_
_
_
M
S
F
D
P
N
L
L
H
Site 2
Y16
H
N
N
G
H
N
G
Y
P
N
G
T
S
A
A
Site 3
S21
N
G
Y
P
N
G
T
S
A
A
L
R
E
T
G
Site 4
S43
S
Y
G
F
I
Q
C
S
E
R
Q
A
R
L
F
Site 5
S74
D
D
V
E
F
E
V
S
S
D
R
R
T
G
K
Site 6
S75
D
V
E
F
E
V
S
S
D
R
R
T
G
K
P
Site 7
T79
E
V
S
S
D
R
R
T
G
K
P
I
A
V
K
Site 8
S114
A
V
P
H
N
L
E
S
K
S
P
A
A
P
G
Site 9
S116
P
H
N
L
E
S
K
S
P
A
A
P
G
Q
S
Site 10
S123
S
P
A
A
P
G
Q
S
P
T
G
S
V
C
Y
Site 11
S127
P
G
Q
S
P
T
G
S
V
C
Y
E
R
N
G
Site 12
Y130
S
P
T
G
S
V
C
Y
E
R
N
G
E
V
F
Site 13
Y138
E
R
N
G
E
V
F
Y
L
T
Y
T
P
E
D
Site 14
T140
N
G
E
V
F
Y
L
T
Y
T
P
E
D
V
E
Site 15
Y141
G
E
V
F
Y
L
T
Y
T
P
E
D
V
E
G
Site 16
T142
E
V
F
Y
L
T
Y
T
P
E
D
V
E
G
N
Site 17
T168
V
I
D
N
N
K
H
T
G
A
V
S
A
R
N
Site 18
S172
N
K
H
T
G
A
V
S
A
R
N
I
M
L
L
Site 19
Y213
V
K
E
I
F
F
H
Y
S
E
F
K
G
D
L
Site 20
S214
K
E
I
F
F
H
Y
S
E
F
K
G
D
L
E
Site 21
T222
E
F
K
G
D
L
E
T
L
Q
P
G
D
D
V
Site 22
T232
P
G
D
D
V
E
F
T
I
K
D
R
N
G
K
Site 23
T266
S
I
E
H
F
E
G
T
V
T
K
V
I
P
K
Site 24
T268
E
H
F
E
G
T
V
T
K
V
I
P
K
V
P
Site 25
S276
K
V
I
P
K
V
P
S
K
N
Q
N
D
P
L
Site 26
T304
L
P
F
G
D
K
D
T
K
S
K
V
T
L
L
Site 27
S306
F
G
D
K
D
T
K
S
K
V
T
L
L
E
G
Site 28
S321
D
H
V
R
F
N
I
S
T
D
R
R
D
K
L
Site 29
T322
H
V
R
F
N
I
S
T
D
R
R
D
K
L
E
Site 30
T332
R
D
K
L
E
R
A
T
N
I
E
V
L
S
N
Site 31
T340
N
I
E
V
L
S
N
T
F
Q
F
T
N
E
A
Site 32
S401
T
V
V
P
D
M
L
S
A
Q
R
N
H
A
I
Site 33
T417
I
K
K
L
P
K
G
T
V
S
F
H
S
H
S
Site 34
S419
K
L
P
K
G
T
V
S
F
H
S
H
S
D
H
Site 35
S422
K
G
T
V
S
F
H
S
H
S
D
H
R
F
L
Site 36
S424
T
V
S
F
H
S
H
S
D
H
R
F
L
G
T
Site 37
T431
S
D
H
R
F
L
G
T
V
E
K
E
A
T
F
Site 38
T437
G
T
V
E
K
E
A
T
F
S
N
P
K
T
T
Site 39
S439
V
E
K
E
A
T
F
S
N
P
K
T
T
S
P
Site 40
T443
A
T
F
S
N
P
K
T
T
S
P
N
K
G
K
Site 41
T444
T
F
S
N
P
K
T
T
S
P
N
K
G
K
E
Site 42
S445
F
S
N
P
K
T
T
S
P
N
K
G
K
E
K
Site 43
T481
A
K
D
V
E
G
S
T
S
P
Q
I
G
D
K
Site 44
S482
K
D
V
E
G
S
T
S
P
Q
I
G
D
K
V
Site 45
S492
I
G
D
K
V
E
F
S
I
S
D
K
Q
R
P
Site 46
S494
D
K
V
E
F
S
I
S
D
K
Q
R
P
G
Q
Site 47
T505
R
P
G
Q
Q
V
A
T
C
V
R
L
L
G
R
Site 48
S514
V
R
L
L
G
R
N
S
N
S
K
R
L
L
G
Site 49
S516
L
L
G
R
N
S
N
S
K
R
L
L
G
Y
V
Site 50
Y522
N
S
K
R
L
L
G
Y
V
A
T
L
K
D
N
Site 51
Y546
D
K
E
I
F
F
H
Y
S
E
F
S
G
D
V
Site 52
S547
K
E
I
F
F
H
Y
S
E
F
S
G
D
V
D
Site 53
S555
E
F
S
G
D
V
D
S
L
E
L
G
D
M
V
Site 54
Y564
E
L
G
D
M
V
E
Y
S
L
S
K
G
K
G
Site 55
S565
L
G
D
M
V
E
Y
S
L
S
K
G
K
G
N
Site 56
S567
D
M
V
E
Y
S
L
S
K
G
K
G
N
K
V
Site 57
S575
K
G
K
G
N
K
V
S
A
E
K
V
N
K
T
Site 58
T582
S
A
E
K
V
N
K
T
H
S
V
N
G
I
T
Site 59
S584
E
K
V
N
K
T
H
S
V
N
G
I
T
E
E
Site 60
T595
I
T
E
E
A
D
P
T
I
Y
S
G
K
V
I
Site 61
Y597
E
E
A
D
P
T
I
Y
S
G
K
V
I
R
P
Site 62
S607
K
V
I
R
P
L
R
S
V
D
P
T
Q
T
E
Site 63
T611
P
L
R
S
V
D
P
T
Q
T
E
Y
Q
G
M
Site 64
Y615
V
D
P
T
Q
T
E
Y
Q
G
M
I
E
I
V
Site 65
T671
Q
T
M
A
Y
N
I
T
P
L
R
R
A
T
V
Site 66
T677
I
T
P
L
R
R
A
T
V
E
C
V
K
D
Q
Site 67
Y690
D
Q
F
G
F
I
N
Y
E
V
G
D
S
K
K
Site 68
S720
A
G
D
E
V
E
F
S
V
I
L
N
Q
R
T
Site 69
T761
V
N
R
L
K
N
I
T
L
D
D
A
S
A
P
Site 70
S782
Q
P
R
G
P
D
N
S
M
G
F
G
A
E
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation