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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
REM1
Full Name:
GTP-binding protein REM 1
Alias:
GTPase-regulating endothelial cell sprouting; Rad and Gem-like GTP-binding protein 1
Type:
Uncharacterized protein
Mass (Da):
32947
Number AA:
298
UniProt ID:
O75628
International Prot ID:
IPI00289912
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016020
Uniprot
OncoNet
Molecular Function:
GO:0005525
GO:0003924
GO:0005516
PhosphoSite+
KinaseNET
Biological Process:
GO:0007264
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T11
N
T
E
Q
E
A
K
T
P
L
H
R
R
A
S
Site 2
S18
T
P
L
H
R
R
A
S
T
P
L
P
L
S
P
Site 3
T19
P
L
H
R
R
A
S
T
P
L
P
L
S
P
R
Site 4
S24
A
S
T
P
L
P
L
S
P
R
G
H
Q
P
G
Site 5
S34
G
H
Q
P
G
R
L
S
T
V
P
S
T
Q
S
Site 6
T35
H
Q
P
G
R
L
S
T
V
P
S
T
Q
S
Q
Site 7
S38
G
R
L
S
T
V
P
S
T
Q
S
Q
H
P
R
Site 8
T39
R
L
S
T
V
P
S
T
Q
S
Q
H
P
R
L
Site 9
S41
S
T
V
P
S
T
Q
S
Q
H
P
R
L
G
Q
Site 10
S51
P
R
L
G
Q
S
A
S
L
N
P
P
T
Q
K
Site 11
T56
S
A
S
L
N
P
P
T
Q
K
P
S
P
A
P
Site 12
S60
N
P
P
T
Q
K
P
S
P
A
P
D
D
W
S
Site 13
S67
S
P
A
P
D
D
W
S
S
E
S
S
D
S
E
Site 14
S68
P
A
P
D
D
W
S
S
E
S
S
D
S
E
G
Site 15
S70
P
D
D
W
S
S
E
S
S
D
S
E
G
S
W
Site 16
S71
D
D
W
S
S
E
S
S
D
S
E
G
S
W
E
Site 17
S73
W
S
S
E
S
S
D
S
E
G
S
W
E
A
L
Site 18
S98
V
G
K
T
S
L
A
S
L
F
A
G
K
Q
E
Site 19
Y117
E
Q
L
G
E
D
V
Y
E
R
T
L
T
V
D
Site 20
T122
D
V
Y
E
R
T
L
T
V
D
G
E
D
T
T
Site 21
S144
E
A
E
K
L
D
K
S
W
S
Q
E
S
C
L
Site 22
S146
E
K
L
D
K
S
W
S
Q
E
S
C
L
Q
G
Site 23
S149
D
K
S
W
S
Q
E
S
C
L
Q
G
G
S
A
Site 24
S168
Y
S
I
A
D
R
G
S
F
E
S
A
S
E
L
Site 25
S171
A
D
R
G
S
F
E
S
A
S
E
L
R
I
Q
Site 26
S173
R
G
S
F
E
S
A
S
E
L
R
I
Q
L
R
Site 27
T182
L
R
I
Q
L
R
R
T
H
Q
A
D
H
V
P
Site 28
S206
L
A
R
C
R
E
V
S
V
E
E
G
R
A
C
Site 29
T227
K
F
I
E
T
S
A
T
L
Q
H
N
V
A
E
Site 30
S250
L
R
L
R
R
R
D
S
A
A
K
E
P
P
A
Site 31
S263
P
A
P
R
R
P
A
S
L
A
Q
R
A
R
R
Site 32
T276
R
R
F
L
A
R
L
T
A
R
S
A
R
R
R
Site 33
S279
L
A
R
L
T
A
R
S
A
R
R
R
A
L
K
Site 34
S289
R
R
A
L
K
A
R
S
K
S
C
H
N
L
A
Site 35
S291
A
L
K
A
R
S
K
S
C
H
N
L
A
V
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation