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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SERPINB7
Full Name:
Serpin B7
Alias:
Megsin
Type:
Mass (Da):
42887
Number AA:
380
UniProt ID:
O75635
International Prot ID:
IPI00021555
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0044424
GO:0044464
Uniprot
OncoNet
Molecular Function:
GO:0004857
GO:0004866
GO:0004867
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S50
R
L
G
A
Q
D
D
S
L
S
Q
I
D
K
L
Site 2
S52
G
A
Q
D
D
S
L
S
Q
I
D
K
L
L
H
Site 3
T62
D
K
L
L
H
V
N
T
A
S
G
Y
G
N
S
Site 4
S64
L
L
H
V
N
T
A
S
G
Y
G
N
S
S
N
Site 5
Y66
H
V
N
T
A
S
G
Y
G
N
S
S
N
S
Q
Site 6
S69
T
A
S
G
Y
G
N
S
S
N
S
Q
S
G
L
Site 7
S70
A
S
G
Y
G
N
S
S
N
S
Q
S
G
L
Q
Site 8
S72
G
Y
G
N
S
S
N
S
Q
S
G
L
Q
S
Q
Site 9
S74
G
N
S
S
N
S
Q
S
G
L
Q
S
Q
L
K
Site 10
S78
N
S
Q
S
G
L
Q
S
Q
L
K
R
V
F
S
Site 11
S85
S
Q
L
K
R
V
F
S
D
I
N
A
S
H
K
Site 12
Y94
I
N
A
S
H
K
D
Y
D
L
S
I
V
N
G
Site 13
S97
S
H
K
D
Y
D
L
S
I
V
N
G
L
F
A
Site 14
Y114
V
Y
G
F
H
K
D
Y
I
E
C
A
E
K
L
Site 15
Y122
I
E
C
A
E
K
L
Y
D
A
K
V
E
R
V
Site 16
S197
T
I
N
C
H
F
K
S
P
K
C
S
G
K
A
Site 17
S217
Q
E
R
K
F
N
L
S
V
I
E
D
P
S
M
Site 18
S223
L
S
V
I
E
D
P
S
M
K
I
L
E
L
R
Site 19
Y238
Y
N
G
G
I
N
M
Y
V
L
L
P
E
N
D
Site 20
S247
L
L
P
E
N
D
L
S
E
I
E
N
K
L
T
Site 21
T254
S
E
I
E
N
K
L
T
F
Q
N
L
M
E
W
Site 22
T262
F
Q
N
L
M
E
W
T
N
P
R
R
M
T
S
Site 23
T268
W
T
N
P
R
R
M
T
S
K
Y
V
E
V
F
Site 24
S269
T
N
P
R
R
M
T
S
K
Y
V
E
V
F
F
Site 25
Y271
P
R
R
M
T
S
K
Y
V
E
V
F
F
P
Q
Site 26
Y290
K
N
Y
E
M
K
Q
Y
L
R
A
L
G
L
K
Site 27
S303
L
K
D
I
F
D
E
S
K
A
D
L
S
G
I
Site 28
S308
D
E
S
K
A
D
L
S
G
I
A
S
G
G
R
Site 29
Y317
I
A
S
G
G
R
L
Y
I
S
R
M
M
H
K
Site 30
S319
S
G
G
R
L
Y
I
S
R
M
M
H
K
S
Y
Site 31
S325
I
S
R
M
M
H
K
S
Y
I
E
V
T
E
E
Site 32
Y326
S
R
M
M
H
K
S
Y
I
E
V
T
E
E
G
Site 33
S352
V
E
K
Q
L
P
Q
S
T
L
F
R
A
D
H
Site 34
T353
E
K
Q
L
P
Q
S
T
L
F
R
A
D
H
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation