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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TRPA1
Full Name:
Transient receptor potential cation channel subfamily A member 1
Alias:
Ankyrin-like with transmembrane domains protein 1;Transformation-sensitive protein p120
Type:
Mass (Da):
127487
Number AA:
1119
UniProt ID:
O75762
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y22
K
E
P
Q
G
V
V
Y
E
D
V
P
D
D
T
Site 2
T29
Y
E
D
V
P
D
D
T
E
D
F
K
E
S
L
Site 3
S35
D
T
E
D
F
K
E
S
L
K
V
V
F
E
G
Site 4
Y45
V
V
F
E
G
S
A
Y
G
L
Q
N
F
N
K
Site 5
S86
M
E
K
I
T
R
D
S
S
L
E
V
L
H
E
Site 6
S87
E
K
I
T
R
D
S
S
L
E
V
L
H
E
M
Site 7
Y97
V
L
H
E
M
D
D
Y
G
N
T
P
L
H
C
Site 8
S113
V
E
K
N
Q
I
E
S
V
K
F
L
L
S
R
Site 9
S119
E
S
V
K
F
L
L
S
R
G
A
N
P
N
L
Site 10
S208
P
I
H
Q
A
A
F
S
G
S
K
E
C
M
E
Site 11
Y226
R
F
G
E
E
H
G
Y
S
R
Q
L
H
I
N
Site 12
T241
F
M
N
N
G
K
A
T
P
L
H
L
A
V
Q
Site 13
S317
E
T
M
L
H
R
A
S
L
F
D
H
H
E
L
Site 14
Y327
D
H
H
E
L
A
D
Y
L
I
S
V
G
A
D
Site 15
S340
A
D
I
N
K
I
D
S
E
G
R
S
P
L
I
Site 16
S344
K
I
D
S
E
G
R
S
P
L
I
L
A
T
A
Site 17
S354
I
L
A
T
A
S
A
S
W
N
I
V
N
L
L
Site 18
S363
N
I
V
N
L
L
L
S
K
G
A
Q
V
D
I
Site 19
T382
G
R
N
F
L
H
L
T
V
Q
Q
P
Y
G
L
Site 20
Y419
D
G
C
T
P
L
H
Y
A
C
R
Q
G
G
P
Site 21
S428
C
R
Q
G
G
P
G
S
V
N
N
L
L
G
F
Site 22
S438
N
L
L
G
F
N
V
S
I
H
S
K
S
K
D
Site 23
S443
N
V
S
I
H
S
K
S
K
D
K
K
S
P
L
Site 24
S448
S
K
S
K
D
K
K
S
P
L
H
F
A
A
S
Site 25
S455
S
P
L
H
F
A
A
S
Y
G
R
I
N
T
C
Site 26
Y456
P
L
H
F
A
A
S
Y
G
R
I
N
T
C
Q
Site 27
T461
A
S
Y
G
R
I
N
T
C
Q
R
L
L
Q
D
Site 28
S470
Q
R
L
L
Q
D
I
S
D
T
R
L
L
N
E
Site 29
T484
E
G
D
L
H
G
M
T
P
L
H
L
A
A
K
Site 30
S510
K
K
G
A
L
F
L
S
D
H
N
G
W
T
A
Site 31
T529
S
M
G
G
Y
T
Q
T
M
K
V
I
L
D
T
Site 32
T550
R
L
D
E
D
G
N
T
A
L
H
F
A
A
R
Site 33
T598
K
R
K
E
V
V
L
T
I
I
R
S
K
R
W
Site 34
S616
L
K
I
F
S
H
N
S
P
G
N
K
C
P
I
Site 35
T624
P
G
N
K
C
P
I
T
E
M
I
E
Y
L
P
Site 36
Y654
E
D
K
S
C
R
D
Y
Y
I
E
Y
N
F
K
Site 37
Y655
D
K
S
C
R
D
Y
Y
I
E
Y
N
F
K
Y
Site 38
Y662
Y
I
E
Y
N
F
K
Y
L
Q
C
P
L
E
F
Site 39
T673
P
L
E
F
T
K
K
T
P
T
Q
D
V
I
Y
Site 40
Y680
T
P
T
Q
D
V
I
Y
E
P
L
T
A
L
N
Site 41
T755
S
T
G
I
I
N
E
T
S
D
H
S
E
I
L
Site 42
S756
T
G
I
I
N
E
T
S
D
H
S
E
I
L
D
Site 43
T764
D
H
S
E
I
L
D
T
T
N
S
Y
L
I
K
Site 44
T765
H
S
E
I
L
D
T
T
N
S
Y
L
I
K
T
Site 45
Y799
I
F
Q
Q
K
R
N
Y
F
M
D
I
S
N
V
Site 46
Y918
M
M
L
G
D
I
N
Y
R
E
S
F
L
E
P
Site 47
S921
G
D
I
N
Y
R
E
S
F
L
E
P
Y
L
R
Site 48
Y926
R
E
S
F
L
E
P
Y
L
R
N
E
L
A
H
Site 49
S972
A
E
V
Q
K
H
A
S
L
K
R
I
A
M
Q
Site 50
S985
M
Q
V
E
L
H
T
S
L
E
K
K
L
P
L
Site 51
S1002
L
R
K
V
D
Q
K
S
T
I
V
Y
P
N
K
Site 52
Y1006
D
Q
K
S
T
I
V
Y
P
N
K
P
R
S
G
Site 53
S1012
V
Y
P
N
K
P
R
S
G
G
M
L
F
H
I
Site 54
S1039
E
I
P
N
A
D
K
S
L
E
M
E
I
L
K
Site 55
T1055
K
Y
R
L
K
D
L
T
F
L
L
E
K
Q
H
Site 56
T1078
K
M
E
I
I
S
E
T
E
D
D
D
S
H
C
Site 57
S1083
S
E
T
E
D
D
D
S
H
C
S
F
Q
D
R
Site 58
S1086
E
D
D
D
S
H
C
S
F
Q
D
R
F
K
K
Site 59
S1101
E
Q
M
E
Q
R
N
S
R
W
N
T
V
L
R
Site 60
T1105
Q
R
N
S
R
W
N
T
V
L
R
A
V
K
A
Site 61
T1114
L
R
A
V
K
A
K
T
H
H
L
E
P
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation