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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Tcea3
Full Name:
Transcription elongation factor A protein 3
Alias:
Tfiis; Tfiis.h
Type:
Nucleus protein
Mass (Da):
38972
Number AA:
348
UniProt ID:
O75764
International Prot ID:
IPI00178146
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0003702
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006354
GO:0006357
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T23
K
M
V
A
R
K
N
T
E
G
A
L
D
L
L
Site 2
S35
D
L
L
K
K
L
H
S
C
Q
M
S
I
Q
L
Site 3
S39
K
L
H
S
C
Q
M
S
I
Q
L
L
Q
T
T
Site 4
S60
N
G
V
R
K
H
C
S
D
K
E
V
V
S
L
Site 5
S81
N
W
K
R
L
L
D
S
P
G
P
P
K
G
E
Site 6
S106
K
E
K
G
L
E
C
S
D
W
K
P
E
A
G
Site 7
S115
W
K
P
E
A
G
L
S
P
P
R
K
K
R
E
Site 8
T126
K
K
R
E
D
P
K
T
R
R
D
S
V
D
S
Site 9
S130
D
P
K
T
R
R
D
S
V
D
S
K
S
S
A
Site 10
S133
T
R
R
D
S
V
D
S
K
S
S
A
S
S
S
Site 11
S135
R
D
S
V
D
S
K
S
S
A
S
S
S
P
K
Site 12
S136
D
S
V
D
S
K
S
S
A
S
S
S
P
K
R
Site 13
S138
V
D
S
K
S
S
A
S
S
S
P
K
R
P
S
Site 14
S139
D
S
K
S
S
A
S
S
S
P
K
R
P
S
V
Site 15
S140
S
K
S
S
A
S
S
S
P
K
R
P
S
V
E
Site 16
S145
S
S
S
P
K
R
P
S
V
E
R
S
N
S
S
Site 17
S149
K
R
P
S
V
E
R
S
N
S
S
K
S
K
A
Site 18
S151
P
S
V
E
R
S
N
S
S
K
S
K
A
E
S
Site 19
S152
S
V
E
R
S
N
S
S
K
S
K
A
E
S
P
Site 20
S154
E
R
S
N
S
S
K
S
K
A
E
S
P
K
T
Site 21
S158
S
S
K
S
K
A
E
S
P
K
T
P
S
S
P
Site 22
T161
S
K
A
E
S
P
K
T
P
S
S
P
L
T
P
Site 23
S163
A
E
S
P
K
T
P
S
S
P
L
T
P
T
F
Site 24
S164
E
S
P
K
T
P
S
S
P
L
T
P
T
F
A
Site 25
T167
K
T
P
S
S
P
L
T
P
T
F
A
S
S
M
Site 26
S186
P
C
Y
L
T
G
D
S
V
R
D
K
C
V
E
Site 27
Y205
A
L
K
A
D
D
D
Y
K
D
Y
G
V
N
C
Site 28
Y208
A
D
D
D
Y
K
D
Y
G
V
N
C
D
K
M
Site 29
Y224
S
E
I
E
D
H
I
Y
Q
E
L
K
S
T
D
Site 30
T230
I
Y
Q
E
L
K
S
T
D
M
K
Y
R
N
R
Site 31
Y234
L
K
S
T
D
M
K
Y
R
N
R
V
R
S
R
Site 32
S240
K
Y
R
N
R
V
R
S
R
I
S
N
L
K
D
Site 33
S243
N
R
V
R
S
R
I
S
N
L
K
D
P
R
N
Site 34
T271
A
G
L
I
A
K
M
T
A
E
E
M
A
S
D
Site 35
S277
M
T
A
E
E
M
A
S
D
E
L
R
E
L
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation