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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RHBDL1
Full Name:
Rhomboid-related protein 1
Alias:
EC 3.4.21.105; RHBDL; RHBL1; Rhomboid; RRP
Type:
Uncharacterized protein
Mass (Da):
48314
Number AA:
438
UniProt ID:
O75783
International Prot ID:
Isoform1 - IPI00022577
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005887
GO:0005624
Uniprot
OncoNet
Molecular Function:
GO:0004252
PhosphoSite+
KinaseNET
Biological Process:
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
G
R
V
E
D
G
G
T
T
E
E
L
E
D
W
Site 2
T20
L
E
D
W
D
P
G
T
S
A
L
P
A
P
G
Site 3
S21
E
D
W
D
P
G
T
S
A
L
P
A
P
G
I
Site 4
T36
K
Q
G
P
R
E
Q
T
G
T
G
P
L
S
Q
Site 5
T38
G
P
R
E
Q
T
G
T
G
P
L
S
Q
K
C
Site 6
S42
Q
T
G
T
G
P
L
S
Q
K
C
W
E
P
E
Site 7
S54
E
P
E
P
D
A
P
S
Q
P
G
P
A
L
W
Site 8
T68
W
S
R
G
R
A
R
T
Q
A
L
A
G
G
S
Site 9
S76
Q
A
L
A
G
G
S
S
L
Q
Q
L
D
P
E
Site 10
S99
T
F
T
G
L
V
H
S
H
E
L
P
L
D
P
Site 11
S134
Q
E
L
V
D
L
I
S
S
K
R
S
S
S
F
Site 12
S135
E
L
V
D
L
I
S
S
K
R
S
S
S
F
K
Site 13
S138
D
L
I
S
S
K
R
S
S
S
F
K
R
A
I
Site 14
S139
L
I
S
S
K
R
S
S
S
F
K
R
A
I
A
Site 15
S140
I
S
S
K
R
S
S
S
F
K
R
A
I
A
N
Site 16
Y166
D
E
P
G
L
G
V
Y
K
R
F
V
R
Y
V
Site 17
Y172
V
Y
K
R
F
V
R
Y
V
A
Y
E
I
L
P
Site 18
Y175
R
F
V
R
Y
V
A
Y
E
I
L
P
C
E
V
Site 19
Y230
L
Q
T
Y
H
P
E
Y
M
K
S
P
L
V
Y
Site 20
Y237
Y
M
K
S
P
L
V
Y
H
P
G
H
R
A
R
Site 21
S362
R
A
V
W
L
R
F
S
P
P
L
P
A
S
G
Site 22
S368
F
S
P
P
L
P
A
S
G
P
Q
P
S
F
M
Site 23
S373
P
A
S
G
P
Q
P
S
F
M
A
H
L
A
G
Site 24
S394
M
G
L
T
I
L
R
S
Y
E
E
R
L
R
D
Site 25
Y395
G
L
T
I
L
R
S
Y
E
E
R
L
R
D
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation