KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
CDC123
Full Name:
Cell division cycle protein 123 homolog
Alias:
CD123; Cell division cycle 123; D123; PZ32
Type:
Cell cycle protein for S phase entry. CDC123 family member.
Mass (Da):
39135
Number AA:
336
UniProt ID:
O75794
International Prot ID:
IPI00005670
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0007050
GO:0051301
GO:0008284
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y37
L
P
Q
N
V
K
D
Y
L
L
D
D
G
T
L
Site 2
T43
D
Y
L
L
D
D
G
T
L
V
V
S
G
R
D
Site 3
S47
D
D
G
T
L
V
V
S
G
R
D
D
P
P
T
Site 4
T54
S
G
R
D
D
P
P
T
H
S
Q
P
D
S
D
Site 5
S56
R
D
D
P
P
T
H
S
Q
P
D
S
D
D
E
Site 6
S60
P
T
H
S
Q
P
D
S
D
D
E
A
E
E
I
Site 7
S70
E
A
E
E
I
Q
W
S
D
D
E
N
T
A
T
Site 8
T77
S
D
D
E
N
T
A
T
L
T
A
P
E
F
P
Site 9
T79
D
E
N
T
A
T
L
T
A
P
E
F
P
E
F
Site 10
Y114
W
S
A
P
R
D
A
Y
W
I
A
M
N
S
S
Site 11
T141
F
K
S
S
D
F
I
T
R
D
F
T
Q
P
F
Site 12
Y162
S
P
D
P
C
I
E
Y
E
L
V
L
R
K
W
Site 13
S191
E
N
K
L
I
G
I
S
Q
R
D
Y
T
Q
Y
Site 14
Y195
I
G
I
S
Q
R
D
Y
T
Q
Y
Y
D
H
I
Site 15
T196
G
I
S
Q
R
D
Y
T
Q
Y
Y
D
H
I
S
Site 16
Y198
S
Q
R
D
Y
T
Q
Y
Y
D
H
I
S
K
Q
Site 17
Y199
Q
R
D
Y
T
Q
Y
Y
D
H
I
S
K
Q
K
Site 18
Y223
F
F
K
K
H
I
Q
Y
K
F
L
D
E
D
F
Site 19
Y235
E
D
F
V
F
D
I
Y
R
D
S
R
G
K
V
Site 20
S256
P
F
G
E
V
T
D
S
L
L
F
T
W
E
E
Site 21
S275
N
N
L
N
G
D
F
S
E
V
D
A
Q
E
Q
Site 22
S284
V
D
A
Q
E
Q
D
S
P
A
F
R
C
T
N
Site 23
T290
D
S
P
A
F
R
C
T
N
S
E
V
T
V
Q
Site 24
T295
R
C
T
N
S
E
V
T
V
Q
P
S
P
Y
L
Site 25
S299
S
E
V
T
V
Q
P
S
P
Y
L
S
Y
R
L
Site 26
Y301
V
T
V
Q
P
S
P
Y
L
S
Y
R
L
P
K
Site 27
S303
V
Q
P
S
P
Y
L
S
Y
R
L
P
K
D
F
Site 28
Y304
Q
P
S
P
Y
L
S
Y
R
L
P
K
D
F
V
Site 29
S314
P
K
D
F
V
D
L
S
T
G
E
D
A
H
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation