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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SOLH
Full Name:
Calpain-15
Alias:
Small optic lobes homologue
Type:
Mass (Da):
117296
Number AA:
1086
UniProt ID:
O75808
International Prot ID:
IPI00024190
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
GO:0044464
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0003677
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0006508
GO:0008152
GO:0009987
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T13
E
W
S
C
V
R
C
T
F
L
N
P
A
G
Q
Site 2
S24
P
A
G
Q
R
Q
C
S
I
C
E
A
P
R
H
Site 3
S42
L
N
H
I
L
R
L
S
V
E
E
Q
K
W
P
Site 4
S100
I
L
G
E
P
K
G
S
C
Q
E
E
A
G
P
Site 5
T157
P
R
C
T
L
H
N
T
P
V
A
S
S
C
S
Site 6
S162
H
N
T
P
V
A
S
S
C
S
V
C
G
G
P
Site 7
S164
T
P
V
A
S
S
C
S
V
C
G
G
P
R
R
Site 8
S173
C
G
G
P
R
R
L
S
L
P
R
I
P
P
E
Site 9
S217
E
A
N
P
P
A
T
S
Q
G
P
A
A
E
P
Site 10
S233
P
P
R
V
P
P
F
S
P
F
S
S
T
L
Q
Site 11
S236
V
P
P
F
S
P
F
S
S
T
L
Q
N
N
P
Site 12
S237
P
P
F
S
P
F
S
S
T
L
Q
N
N
P
V
Site 13
T238
P
F
S
P
F
S
S
T
L
Q
N
N
P
V
P
Site 14
S247
Q
N
N
P
V
P
R
S
R
R
E
V
P
P
Q
Site 15
S266
V
P
E
A
A
Q
P
S
P
S
A
G
C
R
G
Site 16
S268
E
A
A
Q
P
S
P
S
A
G
C
R
G
A
P
Site 17
S296
L
L
S
G
K
R
L
S
V
L
E
E
E
A
T
Site 18
T303
S
V
L
E
E
E
A
T
E
G
G
T
S
R
V
Site 19
S308
E
A
T
E
G
G
T
S
R
V
E
A
G
S
S
Site 20
S314
T
S
R
V
E
A
G
S
S
T
S
G
S
D
I
Site 21
S315
S
R
V
E
A
G
S
S
T
S
G
S
D
I
I
Site 22
Y331
L
A
G
D
T
V
R
Y
T
P
A
S
P
S
S
Site 23
T332
A
G
D
T
V
R
Y
T
P
A
S
P
S
S
P
Site 24
S335
T
V
R
Y
T
P
A
S
P
S
S
P
D
F
T
Site 25
S337
R
Y
T
P
A
S
P
S
S
P
D
F
T
T
W
Site 26
S338
Y
T
P
A
S
P
S
S
P
D
F
T
T
W
S
Site 27
T342
S
P
S
S
P
D
F
T
T
W
S
C
A
K
C
Site 28
T343
P
S
S
P
D
F
T
T
W
S
C
A
K
C
T
Site 29
T355
K
C
T
L
R
N
P
T
V
A
P
R
C
S
A
Site 30
T379
Q
E
H
G
E
P
P
T
H
C
P
D
C
G
A
Site 31
S390
D
C
G
A
D
K
P
S
P
C
G
R
S
C
G
Site 32
S395
K
P
S
P
C
G
R
S
C
G
R
V
S
S
A
Site 33
S400
G
R
S
C
G
R
V
S
S
A
Q
K
A
A
R
Site 34
S401
R
S
C
G
R
V
S
S
A
Q
K
A
A
R
V
Site 35
S456
A
P
L
R
R
R
E
S
M
H
V
E
Q
R
R
Site 36
T465
H
V
E
Q
R
R
Q
T
D
E
G
E
A
K
A
Site 37
S487
F
C
R
E
N
N
V
S
F
V
D
D
S
F
P
Site 38
S492
N
V
S
F
V
D
D
S
F
P
P
G
P
E
S
Site 39
S499
S
F
P
P
G
P
E
S
V
G
F
P
A
G
D
Site 40
S507
V
G
F
P
A
G
D
S
V
Q
Q
R
V
R
Q
Site 41
S524
R
P
Q
E
I
N
C
S
V
F
R
D
H
R
A
Site 42
S576
E
R
V
M
V
T
R
S
L
C
A
E
G
A
Y
Site 43
Y583
S
L
C
A
E
G
A
Y
Q
V
R
L
C
K
D
Site 44
S613
E
A
G
C
L
L
F
S
Q
A
Q
R
K
Q
L
Site 45
S664
E
S
L
A
L
Q
L
S
S
T
N
P
R
E
E
Site 46
T666
L
A
L
Q
L
S
S
T
N
P
R
E
E
P
V
Site 47
T675
P
R
E
E
P
V
D
T
D
L
I
W
A
K
M
Site 48
S706
G
N
M
K
V
D
D
S
A
Y
E
S
L
G
L
Site 49
Y708
M
K
V
D
D
S
A
Y
E
S
L
G
L
R
P
Site 50
S710
V
D
D
S
A
Y
E
S
L
G
L
R
P
R
H
Site 51
Y719
G
L
R
P
R
H
A
Y
S
I
L
D
V
R
D
Site 52
S768
G
E
L
M
P
H
G
S
S
E
G
V
F
W
M
Site 53
Y777
E
G
V
F
W
M
E
Y
G
D
F
V
R
Y
F
Site 54
Y783
E
Y
G
D
F
V
R
Y
F
D
S
V
D
I
C
Site 55
S807
R
V
Q
G
C
F
P
S
S
A
S
A
P
V
G
Site 56
S835
F
A
L
F
Q
E
G
S
R
R
S
D
A
V
D
Site 57
S838
F
Q
E
G
S
R
R
S
D
A
V
D
S
H
L
Site 58
S843
R
R
S
D
A
V
D
S
H
L
L
D
L
C
I
Site 59
S872
L
G
R
L
L
A
H
S
K
R
A
V
K
K
F
Site 60
T908
W
G
P
P
L
P
G
T
P
A
P
Q
A
S
S
Site 61
S914
G
T
P
A
P
Q
A
S
S
P
S
A
G
V
P
Site 62
S915
T
P
A
P
Q
A
S
S
P
S
A
G
V
P
R
Site 63
S924
S
A
G
V
P
R
A
S
P
E
P
P
G
H
V
Site 64
T960
A
D
A
I
I
L
L
T
E
S
R
G
E
R
H
Site 65
Y976
G
R
E
G
M
T
C
Y
Y
L
T
H
G
W
A
Site 66
Y997
E
N
R
H
P
K
A
Y
L
H
V
Q
C
D
C
Site 67
S1012
T
D
S
F
N
V
V
S
T
R
G
S
L
R
T
Site 68
S1016
N
V
V
S
T
R
G
S
L
R
T
Q
D
S
V
Site 69
T1019
S
T
R
G
S
L
R
T
Q
D
S
V
P
P
L
Site 70
S1022
G
S
L
R
T
Q
D
S
V
P
P
L
H
R
Q
Site 71
S1044
L
E
G
N
A
G
F
S
I
T
H
R
L
A
H
Site 72
T1046
G
N
A
G
F
S
I
T
H
R
L
A
H
R
K
Site 73
S1060
K
A
A
Q
A
F
L
S
D
W
T
A
S
K
G
Site 74
T1063
Q
A
F
L
S
D
W
T
A
S
K
G
T
H
S
Site 75
S1065
F
L
S
D
W
T
A
S
K
G
T
H
S
P
P
Site 76
S1070
T
A
S
K
G
T
H
S
P
P
L
T
P
E
V
Site 77
T1074
G
T
H
S
P
P
L
T
P
E
V
A
G
L
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation