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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RPP40
Full Name:
Ribonuclease P protein subunit p40
Alias:
RNase P subunit 1
Type:
Mass (Da):
41834
Number AA:
363
UniProt ID:
O75818
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y37
R
H
L
V
Q
T
H
Y
Y
N
Y
R
V
S
F
Site 2
Y38
H
L
V
Q
T
H
Y
Y
N
Y
R
V
S
F
L
Site 3
Y40
V
Q
T
H
Y
Y
N
Y
R
V
S
F
L
I
P
Site 4
T106
T
H
I
D
E
D
N
T
V
A
L
L
P
N
G
Site 5
S118
P
N
G
K
L
I
L
S
L
D
K
D
T
Y
E
Site 6
T123
I
L
S
L
D
K
D
T
Y
E
E
T
G
L
Q
Site 7
Y124
L
S
L
D
K
D
T
Y
E
E
T
G
L
Q
G
Site 8
S134
T
G
L
Q
G
H
P
S
Q
F
S
G
R
K
I
Site 9
S137
Q
G
H
P
S
Q
F
S
G
R
K
I
M
K
F
Site 10
S154
S
I
D
L
M
E
L
S
L
N
L
D
S
K
K
Site 11
S159
E
L
S
L
N
L
D
S
K
K
Y
E
R
I
S
Site 12
Y162
L
N
L
D
S
K
K
Y
E
R
I
S
W
S
F
Site 13
S166
S
K
K
Y
E
R
I
S
W
S
F
K
E
K
K
Site 14
S168
K
Y
E
R
I
S
W
S
F
K
E
K
K
P
L
Site 15
T186
F
L
L
A
W
H
K
T
G
S
E
E
S
T
M
Site 16
S188
L
A
W
H
K
T
G
S
E
E
S
T
M
M
S
Site 17
S191
H
K
T
G
S
E
E
S
T
M
M
S
Y
F
S
Site 18
T192
K
T
G
S
E
E
S
T
M
M
S
Y
F
S
K
Site 19
S195
S
E
E
S
T
M
M
S
Y
F
S
K
Y
Q
I
Site 20
Y196
E
E
S
T
M
M
S
Y
F
S
K
Y
Q
I
Q
Site 21
Y200
M
M
S
Y
F
S
K
Y
Q
I
Q
E
H
Q
P
Site 22
S212
H
Q
P
K
V
A
L
S
T
L
R
D
L
Q
C
Site 23
T213
Q
P
K
V
A
L
S
T
L
R
D
L
Q
C
P
Site 24
S225
Q
C
P
V
L
Q
S
S
E
L
E
G
T
P
E
Site 25
T230
Q
S
S
E
L
E
G
T
P
E
V
S
C
R
A
Site 26
S249
D
W
L
G
A
V
F
S
N
V
D
L
N
N
E
Site 27
Y264
P
N
N
F
I
S
T
Y
C
C
P
E
P
S
T
Site 28
Y300
L
L
E
H
L
C
H
Y
F
D
E
P
K
L
A
Site 29
S320
S
V
Q
G
F
A
D
S
P
V
S
W
E
K
N
Site 30
S323
G
F
A
D
S
P
V
S
W
E
K
N
E
H
G
Site 31
Y339
R
K
G
G
E
H
L
Y
N
F
V
I
F
N
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation