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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF189
Full Name:
Zinc finger protein 189
Alias:
ZN189
Type:
Mass (Da):
72980
Number AA:
UniProt ID:
O75820
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003700
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0000122
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
A
S
P
S
P
P
P
E
S
K
G
Site 2
S10
S
P
S
P
P
P
E
S
K
G
L
L
T
F
E
Site 3
Y30
F
T
Q
E
E
W
D
Y
L
D
P
A
Q
R
S
Site 4
Y39
D
P
A
Q
R
S
L
Y
K
D
V
M
M
E
N
Site 5
Y47
K
D
V
M
M
E
N
Y
G
N
L
V
S
L
D
Site 6
S52
E
N
Y
G
N
L
V
S
L
D
V
L
N
R
D
Site 7
S89
V
I
V
T
R
I
K
S
E
I
D
Q
D
P
M
Site 8
T100
Q
D
P
M
G
R
E
T
F
E
L
V
G
R
L
Site 9
S122
L
W
E
I
P
R
E
S
L
T
Q
E
Q
R
M
Site 10
T124
E
I
P
R
E
S
L
T
Q
E
Q
R
M
F
R
Site 11
T134
Q
R
M
F
R
E
N
T
N
I
I
R
K
R
P
Site 12
S143
I
I
R
K
R
P
N
S
E
E
K
C
H
K
C
Site 13
T171
I
Q
H
Q
R
V
H
T
G
E
K
P
F
Q
C
Site 14
S184
Q
C
N
E
C
G
K
S
F
S
R
S
S
F
V
Site 15
S186
N
E
C
G
K
S
F
S
R
S
S
F
V
I
E
Site 16
S188
C
G
K
S
F
S
R
S
S
F
V
I
E
H
Q
Site 17
S189
G
K
S
F
S
R
S
S
F
V
I
E
H
Q
R
Site 18
T199
I
E
H
Q
R
I
H
T
G
E
R
P
Y
E
C
Site 19
Y204
I
H
T
G
E
R
P
Y
E
C
N
Y
C
G
K
Site 20
Y208
E
R
P
Y
E
C
N
Y
C
G
K
T
F
S
V
Site 21
T212
E
C
N
Y
C
G
K
T
F
S
V
S
S
T
L
Site 22
S214
N
Y
C
G
K
T
F
S
V
S
S
T
L
I
R
Site 23
S216
C
G
K
T
F
S
V
S
S
T
L
I
R
H
Q
Site 24
T218
K
T
F
S
V
S
S
T
L
I
R
H
Q
R
I
Site 25
T227
I
R
H
Q
R
I
H
T
G
E
R
P
Y
Q
C
Site 26
Y232
I
H
T
G
E
R
P
Y
Q
C
N
Q
C
K
Q
Site 27
S240
Q
C
N
Q
C
K
Q
S
F
S
Q
R
R
S
L
Site 28
S242
N
Q
C
K
Q
S
F
S
Q
R
R
S
L
V
K
Site 29
S246
Q
S
F
S
Q
R
R
S
L
V
K
H
Q
R
I
Site 30
T255
V
K
H
Q
R
I
H
T
G
E
K
P
H
K
C
Site 31
S263
G
E
K
P
H
K
C
S
D
C
G
K
A
F
S
Site 32
S270
S
D
C
G
K
A
F
S
W
K
S
H
L
I
E
Site 33
T281
H
L
I
E
H
Q
R
T
H
T
G
E
K
P
Y
Site 34
T283
I
E
H
Q
R
T
H
T
G
E
K
P
Y
H
C
Site 35
T291
G
E
K
P
Y
H
C
T
K
C
K
K
S
F
S
Site 36
S296
H
C
T
K
C
K
K
S
F
S
R
N
S
L
L
Site 37
S298
T
K
C
K
K
S
F
S
R
N
S
L
L
V
E
Site 38
S301
K
K
S
F
S
R
N
S
L
L
V
E
H
Q
R
Site 39
T311
V
E
H
Q
R
I
H
T
G
E
R
P
H
K
C
Site 40
T329
G
K
A
F
R
L
S
T
Y
L
I
Q
H
Q
K
Site 41
Y330
K
A
F
R
L
S
T
Y
L
I
Q
H
Q
K
I
Site 42
S354
I
E
C
G
K
S
F
S
R
S
S
F
L
I
E
Site 43
S356
C
G
K
S
F
S
R
S
S
F
L
I
E
H
Q
Site 44
S357
G
K
S
F
S
R
S
S
F
L
I
E
H
Q
R
Site 45
T367
I
E
H
Q
R
I
H
T
G
E
R
P
Y
Q
C
Site 46
Y372
I
H
T
G
E
R
P
Y
Q
C
K
E
C
G
K
Site 47
S382
K
E
C
G
K
S
F
S
Q
L
C
N
L
T
R
Site 48
T395
T
R
H
Q
R
I
H
T
G
D
K
P
H
K
C
Site 49
S410
E
E
C
G
K
A
F
S
R
S
S
G
L
I
Q
Site 50
S412
C
G
K
A
F
S
R
S
S
G
L
I
Q
H
Q
Site 51
S413
G
K
A
F
S
R
S
S
G
L
I
Q
H
Q
R
Site 52
T423
I
Q
H
Q
R
I
H
T
R
E
K
T
Y
P
Y
Site 53
T427
R
I
H
T
R
E
K
T
Y
P
Y
N
E
T
K
Site 54
Y428
I
H
T
R
E
K
T
Y
P
Y
N
E
T
K
E
Site 55
Y430
T
R
E
K
T
Y
P
Y
N
E
T
K
E
S
F
Site 56
S436
P
Y
N
E
T
K
E
S
F
D
P
N
C
S
L
Site 57
Y450
L
V
I
Q
Q
E
V
Y
P
K
E
K
S
Y
K
Site 58
Y456
V
Y
P
K
E
K
S
Y
K
C
D
E
C
G
K
Site 59
T464
K
C
D
E
C
G
K
T
F
S
V
S
A
H
L
Site 60
S466
D
E
C
G
K
T
F
S
V
S
A
H
L
V
Q
Site 61
T479
V
Q
H
Q
R
I
H
T
G
E
K
P
Y
L
C
Site 62
Y484
I
H
T
G
E
K
P
Y
L
C
T
V
C
G
K
Site 63
T487
G
E
K
P
Y
L
C
T
V
C
G
K
S
F
S
Site 64
T507
I
E
H
Q
R
I
H
T
G
E
R
P
Y
L
C
Site 65
Y512
I
H
T
G
E
R
P
Y
L
C
R
Q
C
G
K
Site 66
S522
R
Q
C
G
K
S
F
S
Q
L
C
N
L
I
R
Site 67
S550
D
E
C
G
K
A
F
S
R
N
S
G
L
I
Q
Site 68
S553
G
K
A
F
S
R
N
S
G
L
I
Q
H
Q
R
Site 69
T563
I
Q
H
Q
R
I
H
T
G
E
K
P
Y
K
C
Site 70
S576
K
C
E
K
C
D
K
S
F
S
Q
Q
R
S
L
Site 71
S578
E
K
C
D
K
S
F
S
Q
Q
R
S
L
V
N
Site 72
S582
K
S
F
S
Q
Q
R
S
L
V
N
H
Q
K
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation