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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
EIF3G
Full Name:
Eukaryotic translation initiation factor 3 subunit G
Alias:
EIF3 p42; EIF3 p44; EIF-3 RNA-binding subunit; EIF3g; EIF3-p44; EIF3S4; Eukaryotic translation initiation factor 3 subunit 4; Eukaryotic translation initiation factor 3, subunit G; IF34
Type:
Translation protein, initiation complex
Mass (Da):
35611
Number AA:
320
UniProt ID:
O75821
International Prot ID:
IPI00290460
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
GO:0005852
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0000166
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006413
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
P
T
G
D
F
D
S
K
P
S
W
A
D
Q
Site 2
S11
G
D
F
D
S
K
P
S
W
A
D
Q
V
E
E
Site 3
T38
L
K
G
I
P
L
A
T
G
D
T
S
P
E
P
Site 4
T41
I
P
L
A
T
G
D
T
S
P
E
P
E
L
L
Site 5
S42
P
L
A
T
G
D
T
S
P
E
P
E
L
L
P
Site 6
T66
V
I
N
G
N
I
K
T
V
T
E
Y
K
I
D
Site 7
T84
K
K
F
K
I
V
R
T
F
R
I
E
T
R
K
Site 8
T89
V
R
T
F
R
I
E
T
R
K
A
S
K
A
V
Site 9
S93
R
I
E
T
R
K
A
S
K
A
V
A
R
R
K
Site 10
T121
G
P
N
V
A
T
T
T
V
S
D
D
V
S
M
Site 11
S123
N
V
A
T
T
T
V
S
D
D
V
S
M
T
F
Site 12
S127
T
T
V
S
D
D
V
S
M
T
F
I
T
S
K
Site 13
T129
V
S
D
D
V
S
M
T
F
I
T
S
K
E
D
Site 14
S156
L
K
G
Q
K
I
V
S
C
R
I
C
K
G
D
Site 15
T174
T
R
C
P
Y
K
D
T
L
G
P
M
Q
K
E
Site 16
T190
A
E
Q
L
G
L
S
T
G
E
K
E
K
L
P
Site 17
Y213
T
Q
N
K
T
G
K
Y
V
P
P
S
L
R
D
Site 18
S217
T
G
K
Y
V
P
P
S
L
R
D
G
A
S
R
Site 19
S223
P
S
L
R
D
G
A
S
R
R
G
E
S
M
Q
Site 20
S228
G
A
S
R
R
G
E
S
M
Q
P
N
R
R
A
Site 21
T240
R
R
A
D
D
N
A
T
I
R
V
T
N
L
S
Site 22
T244
D
N
A
T
I
R
V
T
N
L
S
E
D
T
R
Site 23
S247
T
I
R
V
T
N
L
S
E
D
T
R
E
T
D
Site 24
T253
L
S
E
D
T
R
E
T
D
L
Q
E
L
F
R
Site 25
S264
E
L
F
R
P
F
G
S
I
S
R
I
Y
L
A
Site 26
S266
F
R
P
F
G
S
I
S
R
I
Y
L
A
K
D
Site 27
Y269
F
G
S
I
S
R
I
Y
L
A
K
D
K
T
T
Site 28
T275
I
Y
L
A
K
D
K
T
T
G
Q
S
K
G
F
Site 29
S286
S
K
G
F
A
F
I
S
F
H
R
R
E
D
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation