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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TNFSF13
Full Name:
Tumor necrosis factor ligand superfamily member 13
Alias:
a proliferation inducing ligand; april; cd256; ligand; proliferation inducing ligand april; proliferation-inducing ligand april; tall2; tnf and apol related ligand tall-2; tnf13; tnfsf13; trdl-1; tumor necrosis factor (ligand) superfamily member 13 transcript variant delta; tumor necrosis factor (ligand) superfamily, member 13; tumor necrosis factor ligand superfamily, member 13; tumor necrosis factor ligand superfamily, member 13 isoform alpha proprotein; tumor necrosis factor ligand superfamily, member 13 isoform beta proprotein; tumor necrosis factor ligand superfamily, member 13 isoform gamma proprotein; tumor necrosis factor-like protein ztnf2; tumor necrosis factor-related death ligand-1alpha; tumor necrosis factor-related death ligand-1beta; tumor necrosis factor-related death ligand-1gamma; unq383/pro715
Type:
Mass (Da):
27430
Number AA:
250
UniProt ID:
O75888
International Prot ID:
IPI00027239
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005615
GO:0016020
Uniprot
OncoNet
Molecular Function:
GO:0005125
GO:0005164
PhosphoSite+
KinaseNET
Biological Process:
GO:0006955
GO:0008284
GO:0048298
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T53
M
A
L
L
T
Q
Q
T
E
L
Q
S
L
R
R
Site 2
S57
T
Q
Q
T
E
L
Q
S
L
R
R
E
V
S
R
Site 3
S63
Q
S
L
R
R
E
V
S
R
L
Q
G
T
G
G
Site 4
T68
E
V
S
R
L
Q
G
T
G
G
P
S
Q
N
G
Site 5
S72
L
Q
G
T
G
G
P
S
Q
N
G
E
G
Y
P
Site 6
Y78
P
S
Q
N
G
E
G
Y
P
W
Q
S
L
P
E
Site 7
S82
G
E
G
Y
P
W
Q
S
L
P
E
Q
S
S
D
Site 8
S88
Q
S
L
P
E
Q
S
S
D
A
L
E
A
W
E
Site 9
S100
A
W
E
N
G
E
R
S
R
K
R
R
A
V
L
Site 10
T108
R
K
R
R
A
V
L
T
Q
K
Q
K
K
Q
H
Site 11
S116
Q
K
Q
K
K
Q
H
S
V
L
H
L
V
P
I
Site 12
S127
L
V
P
I
N
A
T
S
K
D
D
S
D
V
T
Site 13
S131
N
A
T
S
K
D
D
S
D
V
T
E
V
M
W
Site 14
T134
S
K
D
D
S
D
V
T
E
V
M
W
Q
P
A
Site 15
Y153
R
G
L
Q
A
Q
G
Y
G
V
R
I
Q
D
A
Site 16
T192
E
G
Q
G
R
Q
E
T
L
F
R
C
I
R
S
Site 17
S199
T
L
F
R
C
I
R
S
M
P
S
H
P
D
R
Site 18
Y208
P
S
H
P
D
R
A
Y
N
S
C
Y
S
A
G
Site 19
Y212
D
R
A
Y
N
S
C
Y
S
A
G
V
F
H
L
Site 20
S213
R
A
Y
N
S
C
Y
S
A
G
V
F
H
L
H
Site 21
S226
L
H
Q
G
D
I
L
S
V
I
I
P
R
A
R
Site 22
S239
A
R
A
K
L
N
L
S
P
H
G
T
F
L
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation