PhosphoNET

           
Protein Info 
   
Short Name:  DGAT1
Full Name:  Diacylglycerol O-acyltransferase 1
Alias:  ACAT related gene product 1; ACAT-related gene product 1; AGRP1; ARGP1; DGAT; Diglyceride acyltransferase
Type:  Cofactor and Vitamin Metabolism - retinol; Transferase; Lipid Metabolism - glycerolipid; EC 2.3.1.20
Mass (Da):  55278
Number AA:  488
UniProt ID:  O75907
International Prot ID:  IPI00015799
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005829  GO:0005783  GO:0016021 Uniprot OncoNet
Molecular Function:  GO:0004144     PhosphoSite+ KinaseNET
Biological Process:  GO:0019432  GO:0034379   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S6__MGDRGSSRRRRTG
Site 2S7_MGDRGSSRRRRTGS
Site 3T12GSSRRRRTGSRPSSH
Site 4S14SRRRRTGSRPSSHGG
Site 5S17RRTGSRPSSHGGGGP
Site 6S18RTGSRPSSHGGGGPA
Site 7S61DGDAGVGSGHWELRC
Site 8S74RCHRLQDSLFSSDSG
Site 9S77RLQDSLFSSDSGFSN
Site 10S78LQDSLFSSDSGFSNY
Site 11S80DSLFSSDSGFSNYRG
Site 12S83FSSDSGFSNYRGILN
Site 13Y85SDSGFSNYRGILNWC
Site 14S227RARAKAASAGKKASS
Site 15S233ASAGKKASSAAAPHT
Site 16T240SSAAAPHTVSYPDNL
Site 17S242AAAPHTVSYPDNLTY
Site 18Y243AAPHTVSYPDNLTYR
Site 19T248VSYPDNLTYRDLYYF
Site 20Y253NLTYRDLYYFLFAPT
Site 21S270YELNFPRSPRIRKRF
Site 22Y316KPFKDMDYSRIIERL
Site 23S317PFKDMDYSRIIERLL
Site 24Y361QFGDREFYRDWWNSE
Site 25S398KPMLRRGSSKWMART
Site 26S399PMLRRGSSKWMARTG
Site 27Y477LMYVHDYYVLNYEAP
Site 28Y481HDYYVLNYEAPAAEA
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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