PhosphoNET

           
Protein Info 
   
Short Name:  Cyclin K
Full Name:  Cyclin-K
Alias:  CCNK; CYCK
Type:  Protein-serine kinase regulatory subunit, activator, cyclin
Mass (Da):  41293
Number AA:  357
UniProt ID:  O75909
International Prot ID:  IPI00411579
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:  GO:0005515     PhosphoSite+ KinaseNET
Biological Process:  GO:0051301  GO:0007067  GO:0000079 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S8MKENKENSSPSVTSA
Site 2S9KENKENSSPSVTSAN
Site 3S11NKENSSPSVTSANLD
Site 4T13ENSSPSVTSANLDHT
Site 5T34DKKDLAHTPSQLEGL
Site 6S36KDLAHTPSQLEGLDP
Site 7T45LEGLDPATEARYRRE
Site 8Y49DPATEARYRREGARF
Site 9T62RFIFDVGTRLGLHYD
Site 10T109LAGKVEETPKKCKDI
Site 11T119KCKDIIKTARSLLND
Site 12Y167PYQFLLKYAKQLKGD
Site 13T196VNDSLCTTLSLQWEP
Site 14S198DSLCTTLSLQWEPEI
Site 15Y258CHQILDLYSQGKQQM
Site 16S259HQILDLYSQGKQQMP
Site 17T269KQQMPHHTPHQLQQP
Site 18S278HQLQQPPSLQPTPQV
Site 19T282QPPSLQPTPQVPQVQ
Site 20S291QVPQVQQSQPSQSSE
Site 21S294QVQQSQPSQSSEPSQ
Site 22S296QQSQPSQSSEPSQPQ
Site 23S297QSQPSQSSEPSQPQQ
Site 24S300PSQSSEPSQPQQKDP
Site 25S324AQQPKKPSPQPSSPR
Site 26S328KKPSPQPSSPRQVKR
Site 27S329KPSPQPSSPRQVKRA
Site 28S340VKRAVVVSPKEENKA
Site 29T361KIPKIETTHPPLPPA
Site 30T394PPGPVDATDLPKVQI
Site 31S426RPPPPPPSSYMTGMS
Site 32S427PPPPPPSSYMTGMST
Site 33T430PPPSSYMTGMSTTSS
Site 34S433SSYMTGMSTTSSYMS
Site 35T434SYMTGMSTTSSYMSG
Site 36S436MTGMSTTSSYMSGEG
Site 37S437TGMSTTSSYMSGEGY
Site 38Y438GMSTTSSYMSGEGYQ
Site 39S440STTSSYMSGEGYQSL
Site 40Y444SYMSGEGYQSLQSMM
Site 41S446MSGEGYQSLQSMMKT
Site 42S449EGYQSLQSMMKTEGP
Site 43T453SLQSMMKTEGPSYGA
Site 44Y458MKTEGPSYGALPPAY
Site 45Y465YGALPPAYGPPAHLP
Site 46Y478LPYHPHVYPPNPPPP
Site 47S493PVPPPPASFPPPAIP
Site 48T503PPAIPPPTPGYPPPP
Site 49Y506IPPPTPGYPPPPPTY
Site 50T512GYPPPPPTYNPNFPP
Site 51Y513YPPPPPTYNPNFPPP
Site 52T527PPPRLPPTHAVPPHP
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


2019 Kinexus Bioinformatics Corporation