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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RGS9
Full Name:
Regulator of G-protein signaling 9
Alias:
Type:
Mass (Da):
76966
Number AA:
674
UniProt ID:
O75916
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T32
K
D
M
Q
N
P
E
T
G
V
R
M
Q
N
Q
Site 2
S45
N
Q
R
V
L
V
T
S
V
P
H
A
M
T
G
Site 3
S66
I
V
Q
R
L
W
I
S
S
L
E
A
Q
N
L
Site 4
S67
V
Q
R
L
W
I
S
S
L
E
A
Q
N
L
G
Site 5
Y82
N
F
I
V
R
Y
G
Y
I
Y
P
L
Q
D
P
Site 6
Y84
I
V
R
Y
G
Y
I
Y
P
L
Q
D
P
K
N
Site 7
S99
L
I
L
K
P
D
G
S
L
Y
R
F
Q
T
P
Site 8
Y101
L
K
P
D
G
S
L
Y
R
F
Q
T
P
Y
F
Site 9
T105
G
S
L
Y
R
F
Q
T
P
Y
F
W
P
T
Q
Site 10
Y121
W
P
A
E
D
T
D
Y
A
I
Y
L
A
K
R
Site 11
Y124
E
D
T
D
Y
A
I
Y
L
A
K
R
N
I
K
Site 12
Y139
K
K
G
I
L
E
E
Y
E
K
E
N
Y
N
F
Site 13
Y144
E
E
Y
E
K
E
N
Y
N
F
L
N
Q
K
M
Site 14
Y153
F
L
N
Q
K
M
N
Y
K
W
D
F
V
I
M
Site 15
Y178
E
R
N
K
A
D
R
Y
A
L
D
C
Q
E
K
Site 16
Y203
G
M
D
N
V
L
D
Y
G
L
D
R
V
T
N
Site 17
T209
D
Y
G
L
D
R
V
T
N
P
N
E
V
K
V
Site 18
Y231
A
V
K
K
E
I
M
Y
Y
Q
Q
A
L
M
R
Site 19
Y232
V
K
K
E
I
M
Y
Y
Q
Q
A
L
M
R
S
Site 20
S239
Y
Q
Q
A
L
M
R
S
T
V
K
S
S
V
S
Site 21
T240
Q
Q
A
L
M
R
S
T
V
K
S
S
V
S
L
Site 22
Y253
S
L
G
G
I
V
K
Y
S
E
Q
F
S
S
N
Site 23
S254
L
G
G
I
V
K
Y
S
E
Q
F
S
S
N
D
Site 24
S258
V
K
Y
S
E
Q
F
S
S
N
D
A
I
M
S
Site 25
S259
K
Y
S
E
Q
F
S
S
N
D
A
I
M
S
G
Site 26
S265
S
S
N
D
A
I
M
S
G
C
L
P
S
N
P
Site 27
S304
E
R
W
A
F
N
F
S
E
L
I
R
D
P
K
Site 28
S315
R
D
P
K
G
R
Q
S
F
Q
Y
F
L
K
K
Site 29
Y318
K
G
R
Q
S
F
Q
Y
F
L
K
K
E
F
S
Site 30
Y340
E
A
C
E
D
L
K
Y
G
D
Q
S
K
V
K
Site 31
S344
D
L
K
Y
G
D
Q
S
K
V
K
E
K
A
E
Site 32
T376
D
G
K
T
M
D
I
T
V
K
G
L
K
H
P
Site 33
Y386
G
L
K
H
P
H
R
Y
V
L
D
A
A
Q
T
Site 34
S403
Y
M
L
M
K
K
D
S
Y
A
R
Y
L
K
S
Site 35
Y404
M
L
M
K
K
D
S
Y
A
R
Y
L
K
S
P
Site 36
Y407
K
K
D
S
Y
A
R
Y
L
K
S
P
I
Y
K
Site 37
S410
S
Y
A
R
Y
L
K
S
P
I
Y
K
D
M
L
Site 38
Y413
R
Y
L
K
S
P
I
Y
K
D
M
L
A
K
A
Site 39
T426
K
A
I
E
P
Q
E
T
T
K
K
S
S
T
L
Site 40
T432
E
T
T
K
K
S
S
T
L
P
F
M
R
R
H
Site 41
S442
F
M
R
R
H
L
R
S
S
P
S
P
V
I
L
Site 42
S443
M
R
R
H
L
R
S
S
P
S
P
V
I
L
R
Site 43
S445
R
H
L
R
S
S
P
S
P
V
I
L
R
Q
L
Site 44
T464
K
A
R
E
A
A
N
T
V
D
I
T
Q
P
G
Site 45
T468
A
A
N
T
V
D
I
T
Q
P
G
Q
H
M
A
Site 46
S477
P
G
Q
H
M
A
P
S
P
H
L
T
V
Y
T
Site 47
Y483
P
S
P
H
L
T
V
Y
T
G
T
C
M
P
P
Site 48
T486
H
L
T
V
Y
T
G
T
C
M
P
P
S
P
S
Site 49
S491
T
G
T
C
M
P
P
S
P
S
S
P
F
S
S
Site 50
S493
T
C
M
P
P
S
P
S
S
P
F
S
S
S
C
Site 51
S494
C
M
P
P
S
P
S
S
P
F
S
S
S
C
R
Site 52
S497
P
S
P
S
S
P
F
S
S
S
C
R
S
P
R
Site 53
S498
S
P
S
S
P
F
S
S
S
C
R
S
P
R
K
Site 54
S499
P
S
S
P
F
S
S
S
C
R
S
P
R
K
P
Site 55
S502
P
F
S
S
S
C
R
S
P
R
K
P
F
A
S
Site 56
S509
S
P
R
K
P
F
A
S
P
S
R
F
I
R
R
Site 57
S511
R
K
P
F
A
S
P
S
R
F
I
R
R
P
S
Site 58
S518
S
R
F
I
R
R
P
S
T
T
I
C
P
S
P
Site 59
T519
R
F
I
R
R
P
S
T
T
I
C
P
S
P
I
Site 60
T520
F
I
R
R
P
S
T
T
I
C
P
S
P
I
R
Site 61
S532
P
I
R
V
A
L
E
S
S
S
G
L
E
Q
K
Site 62
S545
Q
K
G
E
C
S
G
S
M
A
P
R
G
P
S
Site 63
S552
S
M
A
P
R
G
P
S
V
T
E
S
S
E
A
Site 64
T554
A
P
R
G
P
S
V
T
E
S
S
E
A
S
L
Site 65
S556
R
G
P
S
V
T
E
S
S
E
A
S
L
D
T
Site 66
S557
G
P
S
V
T
E
S
S
E
A
S
L
D
T
S
Site 67
S560
V
T
E
S
S
E
A
S
L
D
T
S
W
P
R
Site 68
T563
S
S
E
A
S
L
D
T
S
W
P
R
S
R
P
Site 69
S564
S
E
A
S
L
D
T
S
W
P
R
S
R
P
R
Site 70
S568
L
D
T
S
W
P
R
S
R
P
R
A
P
P
K
Site 71
S581
P
K
A
R
M
A
L
S
F
S
R
F
L
R
R
Site 72
S607
S
P
K
C
P
A
V
S
H
G
R
V
Q
P
L
Site 73
S626
Q
Q
L
P
R
L
K
S
K
R
V
A
N
F
F
Site 74
S643
K
M
D
V
P
T
G
S
G
T
C
L
M
D
S
Site 75
S650
S
G
T
C
L
M
D
S
E
D
A
G
T
G
E
Site 76
T655
M
D
S
E
D
A
G
T
G
E
S
G
D
R
A
Site 77
T663
G
E
S
G
D
R
A
T
E
K
E
V
I
C
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation