PhosphoNET

           
Protein Info 
   
Short Name:  BCAS2
Full Name:  Pre-mRNA-splicing factor SPF27
Alias:  Breast carcinoma amplified sequence 2; Breast carcinoma-amplified 2; DAM1; DNA amplified in mammary carcinoma 1; DNA amplified in mammary carcinoma 1 protein; Spliceosome-associated SPF 27
Type: 
Mass (Da):  26131
Number AA:  225
UniProt ID:  O75934
International Prot ID:  IPI00025178
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005730  GO:0005681   Uniprot OncoNet
Molecular Function:  GO:0005515     PhosphoSite+ KinaseNET
Biological Process:  GO:0000375  GO:0006397   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T4____MAGTGLVAGEV
Site 2Y23LPYFDQGYEAPGVRE
Site 3T40AALVEEETRRYRPTK
Site 4Y43VEEETRRYRPTKNYL
Site 5T46ETRRYRPTKNYLSYL
Site 6Y49RYRPTKNYLSYLTAP
Site 7S51RPTKNYLSYLTAPDY
Site 8Y52PTKNYLSYLTAPDYS
Site 9Y58SYLTAPDYSAFETDI
Site 10T63PDYSAFETDIMRNEF
Site 11S83RQPIELLSMKRYELP
Site 12Y87ELLSMKRYELPAPSS
Site 13S94YELPAPSSGQKNDIT
Site 14S176NMQLTAGSKLREMES
Site 15S183SKLREMESNWVSLVS
Site 16S187EMESNWVSLVSKNYE
Site 17Y193VSLVSKNYEIERTIV
Site 18T198KNYEIERTIVQLENE
Site 19Y207VQLENEIYQIKQQHG
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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