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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KRT33A
Full Name:
Keratin, type I cuticular Ha3-I
Alias:
Hair keratin, type I Ha3-I;Keratin-33A
Type:
Mass (Da):
45940
Number AA:
404
UniProt ID:
O76009
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
S
Y
S
C
G
L
P
S
L
S
C
R
T
S
C
Site 2
S11
S
C
G
L
P
S
L
S
C
R
T
S
C
S
S
Site 3
T14
L
P
S
L
S
C
R
T
S
C
S
S
R
P
C
Site 4
S15
P
S
L
S
C
R
T
S
C
S
S
R
P
C
V
Site 5
S17
L
S
C
R
T
S
C
S
S
R
P
C
V
P
P
Site 6
S18
S
C
R
T
S
C
S
S
R
P
C
V
P
P
S
Site 7
S25
S
R
P
C
V
P
P
S
C
H
G
C
T
L
P
Site 8
S55
C
E
G
S
F
N
G
S
E
K
E
T
M
Q
F
Site 9
S69
F
L
N
D
R
L
A
S
Y
L
E
K
V
R
Q
Site 10
Y70
L
N
D
R
L
A
S
Y
L
E
K
V
R
Q
L
Site 11
S92
E
N
L
I
R
E
R
S
Q
Q
Q
E
P
L
V
Site 12
Y106
V
C
A
S
Y
Q
S
Y
F
K
T
I
E
E
L
Site 13
T109
S
Y
Q
S
Y
F
K
T
I
E
E
L
Q
Q
K
Site 14
S122
Q
K
I
L
C
S
K
S
E
N
A
R
L
V
V
Site 15
S138
I
D
N
A
K
L
A
S
D
D
F
R
T
K
Y
Site 16
Y145
S
D
D
F
R
T
K
Y
E
T
E
L
S
L
R
Site 17
T147
D
F
R
T
K
Y
E
T
E
L
S
L
R
Q
L
Site 18
S150
T
K
Y
E
T
E
L
S
L
R
Q
L
V
E
S
Site 19
S157
S
L
R
Q
L
V
E
S
D
I
N
G
L
R
R
Site 20
T170
R
R
I
L
D
E
L
T
L
C
R
S
D
L
E
Site 21
S174
D
E
L
T
L
C
R
S
D
L
E
A
Q
V
E
Site 22
T200
N
H
E
Q
E
V
N
T
L
R
C
Q
L
G
D
Site 23
S230
Q
V
L
N
E
T
R
S
Q
Y
E
A
L
V
E
Site 24
Y232
L
N
E
T
R
S
Q
Y
E
A
L
V
E
T
N
Site 25
S261
L
N
K
Q
V
V
S
S
S
E
Q
L
Q
S
Y
Site 26
S262
N
K
Q
V
V
S
S
S
E
Q
L
Q
S
Y
Q
Site 27
S267
S
S
S
E
Q
L
Q
S
Y
Q
A
E
I
I
E
Site 28
Y268
S
S
E
Q
L
Q
S
Y
Q
A
E
I
I
E
L
Site 29
T278
E
I
I
E
L
R
R
T
V
N
A
L
E
I
E
Site 30
S295
A
Q
H
N
L
R
D
S
L
E
N
T
L
T
E
Site 31
T299
L
R
D
S
L
E
N
T
L
T
E
S
E
A
R
Site 32
T301
D
S
L
E
N
T
L
T
E
S
E
A
R
Y
S
Site 33
S303
L
E
N
T
L
T
E
S
E
A
R
Y
S
S
Q
Site 34
Y307
L
T
E
S
E
A
R
Y
S
S
Q
L
S
Q
V
Site 35
S308
T
E
S
E
A
R
Y
S
S
Q
L
S
Q
V
Q
Site 36
S309
E
S
E
A
R
Y
S
S
Q
L
S
Q
V
Q
R
Site 37
S312
A
R
Y
S
S
Q
L
S
Q
V
Q
R
L
I
T
Site 38
T319
S
Q
V
Q
R
L
I
T
N
V
E
S
Q
L
A
Site 39
S330
S
Q
L
A
E
I
R
S
D
L
E
R
Q
N
Q
Site 40
Y339
L
E
R
Q
N
Q
E
Y
Q
V
L
L
D
V
R
Site 41
T355
R
L
E
C
E
I
N
T
Y
R
S
L
L
E
S
Site 42
Y356
L
E
C
E
I
N
T
Y
R
S
L
L
E
S
E
Site 43
S358
C
E
I
N
T
Y
R
S
L
L
E
S
E
D
C
Site 44
S362
T
Y
R
S
L
L
E
S
E
D
C
K
L
P
S
Site 45
S369
S
E
D
C
K
L
P
S
N
P
C
A
T
T
N
Site 46
T382
T
N
A
C
D
K
S
T
G
P
C
I
S
N
P
Site 47
S387
K
S
T
G
P
C
I
S
N
P
C
G
L
R
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation