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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KRT34
Full Name:
Keratin, type I cuticular Ha4
Alias:
Hair keratin, type I Ha4;Keratin-34
Type:
Mass (Da):
49424
Number AA:
436
UniProt ID:
O76011
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
L
Y
A
K
P
P
P
T
I
N
G
I
K
G
L
Site 2
T56
L
P
S
L
G
C
R
T
S
C
S
S
R
P
C
Site 3
S57
P
S
L
G
C
R
T
S
C
S
S
R
P
C
V
Site 4
S59
L
G
C
R
T
S
C
S
S
R
P
C
V
P
P
Site 5
S60
G
C
R
T
S
C
S
S
R
P
C
V
P
P
S
Site 6
S67
S
R
P
C
V
P
P
S
C
H
G
Y
T
L
P
Site 7
Y71
V
P
P
S
C
H
G
Y
T
L
P
G
A
C
N
Site 8
S97
C
E
G
S
F
N
G
S
E
K
E
T
M
Q
F
Site 9
S111
F
L
N
D
R
L
A
S
Y
L
E
K
V
R
Q
Site 10
Y112
L
N
D
R
L
A
S
Y
L
E
K
V
R
Q
L
Site 11
S134
E
K
L
I
Q
E
R
S
Q
Q
Q
E
P
L
L
Site 12
S144
Q
E
P
L
L
C
P
S
Y
Q
S
Y
F
K
T
Site 13
Y145
E
P
L
L
C
P
S
Y
Q
S
Y
F
K
T
I
Site 14
Y148
L
C
P
S
Y
Q
S
Y
F
K
T
I
E
E
L
Site 15
T151
S
Y
Q
S
Y
F
K
T
I
E
E
L
Q
Q
K
Site 16
S180
I
D
N
A
K
L
A
S
D
D
F
R
S
K
Y
Site 17
Y187
S
D
D
F
R
S
K
Y
Q
T
E
Q
S
L
R
Site 18
T189
D
F
R
S
K
Y
Q
T
E
Q
S
L
R
L
L
Site 19
S192
S
K
Y
Q
T
E
Q
S
L
R
L
L
V
E
S
Site 20
S199
S
L
R
L
L
V
E
S
D
I
N
S
I
R
R
Site 21
S203
L
V
E
S
D
I
N
S
I
R
R
I
L
D
E
Site 22
T212
R
R
I
L
D
E
L
T
L
C
K
S
D
L
E
Site 23
S216
D
E
L
T
L
C
K
S
D
L
E
S
Q
V
E
Site 24
S220
L
C
K
S
D
L
E
S
Q
V
E
S
L
R
E
Site 25
S224
D
L
E
S
Q
V
E
S
L
R
E
E
L
I
C
Site 26
T242
N
H
E
E
E
V
N
T
L
R
S
Q
L
G
D
Site 27
S272
Q
V
L
N
E
T
R
S
Q
Y
E
A
L
V
E
Site 28
Y274
L
N
E
T
R
S
Q
Y
E
A
L
V
E
I
N
Site 29
S304
N
K
Q
V
V
S
S
S
E
Q
L
Q
S
C
Q
Site 30
S309
S
S
S
E
Q
L
Q
S
C
Q
A
E
I
I
E
Site 31
T320
E
I
I
E
L
R
R
T
V
N
A
L
E
I
E
Site 32
S337
A
Q
H
N
L
R
D
S
L
E
N
T
L
T
E
Site 33
T341
L
R
D
S
L
E
N
T
L
T
E
S
E
A
H
Site 34
T343
D
S
L
E
N
T
L
T
E
S
E
A
H
Y
S
Site 35
S345
L
E
N
T
L
T
E
S
E
A
H
Y
S
S
Q
Site 36
Y349
L
T
E
S
E
A
H
Y
S
S
Q
L
S
Q
V
Site 37
S350
T
E
S
E
A
H
Y
S
S
Q
L
S
Q
V
Q
Site 38
S351
E
S
E
A
H
Y
S
S
Q
L
S
Q
V
Q
S
Site 39
S354
A
H
Y
S
S
Q
L
S
Q
V
Q
S
L
I
T
Site 40
S358
S
Q
L
S
Q
V
Q
S
L
I
T
N
V
E
S
Site 41
T361
S
Q
V
Q
S
L
I
T
N
V
E
S
Q
L
A
Site 42
Y381
L
E
R
Q
N
Q
E
Y
Q
V
L
L
D
V
R
Site 43
T397
R
L
E
C
E
I
N
T
Y
R
S
L
L
E
S
Site 44
Y398
L
E
C
E
I
N
T
Y
R
S
L
L
E
S
E
Site 45
S400
C
E
I
N
T
Y
R
S
L
L
E
S
E
D
C
Site 46
S404
T
Y
R
S
L
L
E
S
E
D
C
K
L
P
C
Site 47
T416
L
P
C
N
P
C
A
T
T
N
A
S
G
N
S
Site 48
S423
T
T
N
A
S
G
N
S
C
G
P
C
G
T
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation