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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KRT36
Full Name:
Keratin, type I cuticular Ha6
Alias:
HA6; Hair keratin, type I Ha6; HHA6; HKA6; Keratin 36; Keratin, hair, acidic, 6; KRTHA6; Type I hair keratin 6
Type:
Cytoskeletal protein
Mass (Da):
52247
Number AA:
467
UniProt ID:
O76013
International Prot ID:
IPI00008692
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005882
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0030280
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T7
_
M
A
T
Q
T
C
T
P
T
F
S
T
G
S
Site 2
T9
A
T
Q
T
C
T
P
T
F
S
T
G
S
I
K
Site 3
S11
Q
T
C
T
P
T
F
S
T
G
S
I
K
G
L
Site 4
S26
C
G
T
A
G
G
I
S
R
V
S
S
I
R
S
Site 5
S33
S
R
V
S
S
I
R
S
V
G
S
C
R
V
P
Site 6
S50
A
G
A
A
G
Y
I
S
S
A
R
S
G
L
S
Site 7
S51
G
A
A
G
Y
I
S
S
A
R
S
G
L
S
G
Site 8
S54
G
Y
I
S
S
A
R
S
G
L
S
G
L
G
S
Site 9
S57
S
S
A
R
S
G
L
S
G
L
G
S
C
L
P
Site 10
S66
L
G
S
C
L
P
G
S
Y
L
S
S
E
C
H
Site 11
Y67
G
S
C
L
P
G
S
Y
L
S
S
E
C
H
T
Site 12
S69
C
L
P
G
S
Y
L
S
S
E
C
H
T
S
G
Site 13
S70
L
P
G
S
Y
L
S
S
E
C
H
T
S
G
F
Site 14
T74
Y
L
S
S
E
C
H
T
S
G
F
V
G
S
G
Site 15
S75
L
S
S
E
C
H
T
S
G
F
V
G
S
G
G
Site 16
S88
G
G
W
F
C
E
G
S
F
N
G
S
E
K
E
Site 17
S92
C
E
G
S
F
N
G
S
E
K
E
T
M
Q
F
Site 18
Y107
L
N
D
R
L
A
N
Y
L
E
K
V
R
Q
L
Site 19
Y129
E
S
R
I
Q
E
W
Y
E
F
Q
I
P
Y
I
Site 20
Y140
I
P
Y
I
C
P
D
Y
Q
S
Y
F
K
T
I
Site 21
Y143
I
C
P
D
Y
Q
S
Y
F
K
T
I
E
D
F
Site 22
T146
D
Y
Q
S
Y
F
K
T
I
E
D
F
Q
Q
K
Site 23
Y182
A
D
D
F
R
T
K
Y
E
T
E
L
S
L
R
Site 24
T184
D
F
R
T
K
Y
E
T
E
L
S
L
R
Q
L
Site 25
S187
T
K
Y
E
T
E
L
S
L
R
Q
L
V
E
A
Site 26
T207
R
R
I
L
D
E
L
T
L
C
K
A
D
L
E
Site 27
S219
D
L
E
A
Q
V
E
S
L
K
E
E
L
M
C
Site 28
S236
K
N
H
E
E
E
V
S
V
L
R
C
Q
L
G
Site 29
Y269
L
E
D
M
R
C
Q
Y
E
A
L
V
E
N
N
Site 30
S299
N
Q
Q
V
V
S
S
S
E
Q
L
Q
C
C
Q
Site 31
T307
E
Q
L
Q
C
C
Q
T
E
I
I
E
L
R
R
Site 32
T315
E
I
I
E
L
R
R
T
V
N
A
L
E
I
E
Site 33
S328
I
E
L
Q
A
Q
H
S
M
R
N
S
L
E
S
Site 34
S332
A
Q
H
S
M
R
N
S
L
E
S
T
L
A
E
Site 35
S335
S
M
R
N
S
L
E
S
T
L
A
E
T
E
A
Site 36
T336
M
R
N
S
L
E
S
T
L
A
E
T
E
A
R
Site 37
S345
A
E
T
E
A
R
Y
S
S
Q
L
A
Q
M
Q
Site 38
S346
E
T
E
A
R
Y
S
S
Q
L
A
Q
M
Q
C
Site 39
S363
S
N
V
E
A
Q
L
S
E
I
R
C
D
L
E
Site 40
Y376
L
E
R
Q
N
Q
E
Y
Q
V
L
L
D
V
K
Site 41
T392
R
L
E
G
E
I
A
T
Y
R
H
L
L
E
G
Site 42
Y393
L
E
G
E
I
A
T
Y
R
H
L
L
E
G
E
Site 43
T447
G
T
Q
I
R
T
I
T
E
E
I
R
D
G
K
Site 44
S457
I
R
D
G
K
V
I
S
S
R
E
H
V
Q
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation