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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KRTHA7
Full Name:
Keratin, type I cuticular Ha7
Alias:
HA7; HA-7; Hair keratin, type I Ha7; HHA7; HKA7; Keratin 37; Keratin, hair, acidic, 7; KRT37
Type:
Structural protein
Mass (Da):
49747
Number AA:
449
UniProt ID:
O76014
International Prot ID:
IPI00329240
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005882
Uniprot
OncoNet
Molecular Function:
GO:0005198
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
T
S
F
Y
S
T
S
S
C
P
L
G
Site 2
T15
S
S
C
P
L
G
C
T
M
A
P
G
A
R
N
Site 3
S59
A
N
R
V
R
V
G
S
T
P
L
G
R
P
S
Site 4
T60
N
R
V
R
V
G
S
T
P
L
G
R
P
S
L
Site 5
S66
S
T
P
L
G
R
P
S
L
C
L
P
P
T
S
Site 6
T75
C
L
P
P
T
S
H
T
A
C
P
L
P
G
T
Site 7
Y118
L
N
D
R
L
A
N
Y
L
E
K
V
R
Q
L
Site 8
T135
E
N
A
E
L
E
T
T
L
L
E
R
S
K
C
Site 9
S140
E
T
T
L
L
E
R
S
K
C
H
E
S
T
V
Site 10
S145
E
R
S
K
C
H
E
S
T
V
C
P
D
Y
Q
Site 11
T146
R
S
K
C
H
E
S
T
V
C
P
D
Y
Q
S
Site 12
Y151
E
S
T
V
C
P
D
Y
Q
S
Y
F
R
T
I
Site 13
Y154
V
C
P
D
Y
Q
S
Y
F
R
T
I
E
E
L
Site 14
T157
D
Y
Q
S
Y
F
R
T
I
E
E
L
Q
Q
K
Site 15
S195
D
F
R
I
K
L
E
S
E
R
S
L
H
Q
L
Site 16
S198
I
K
L
E
S
E
R
S
L
H
Q
L
V
E
A
Site 17
T218
Q
K
L
L
D
D
A
T
L
A
K
A
D
L
E
Site 18
S237
S
L
K
E
E
Q
L
S
L
K
S
N
H
E
Q
Site 19
S240
E
E
Q
L
S
L
K
S
N
H
E
Q
E
V
K
Site 20
S251
Q
E
V
K
I
L
R
S
Q
L
G
E
K
F
R
Site 21
Y280
L
G
E
M
R
A
Q
Y
E
A
M
V
E
T
N
Site 22
S299
E
Q
W
F
Q
A
Q
S
E
G
I
S
L
Q
A
Site 23
S303
Q
A
Q
S
E
G
I
S
L
Q
A
M
S
C
S
Site 24
S310
S
L
Q
A
M
S
C
S
E
E
L
Q
C
C
Q
Site 25
S318
E
E
L
Q
C
C
Q
S
E
I
L
E
L
R
C
Site 26
T339
V
E
R
Q
A
Q
H
T
L
K
D
C
L
Q
N
Site 27
S347
L
K
D
C
L
Q
N
S
L
C
E
A
E
D
R
Site 28
Y355
L
C
E
A
E
D
R
Y
G
T
E
L
A
Q
M
Site 29
T357
E
A
E
D
R
Y
G
T
E
L
A
Q
M
Q
S
Site 30
S364
T
E
L
A
Q
M
Q
S
L
I
S
N
L
E
E
Site 31
S374
S
N
L
E
E
Q
L
S
E
I
R
A
D
L
E
Site 32
Y387
L
E
R
Q
N
Q
E
Y
Q
V
L
L
D
V
K
Site 33
T403
R
L
E
N
E
I
A
T
Y
R
N
L
L
E
S
Site 34
Y404
L
E
N
E
I
A
T
Y
R
N
L
L
E
S
E
Site 35
S410
T
Y
R
N
L
L
E
S
E
D
C
K
L
P
C
Site 36
S421
K
L
P
C
N
P
C
S
T
P
A
S
C
T
S
Site 37
S425
N
P
C
S
T
P
A
S
C
T
S
C
P
S
C
Site 38
T427
C
S
T
P
A
S
C
T
S
C
P
S
C
G
P
Site 39
S428
S
T
P
A
S
C
T
S
C
P
S
C
G
P
V
Site 40
T436
C
P
S
C
G
P
V
T
G
G
S
P
S
G
H
Site 41
S439
C
G
P
V
T
G
G
S
P
S
G
H
G
A
S
Site 42
S441
P
V
T
G
G
S
P
S
G
H
G
A
S
M
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation