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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KRT38
Full Name:
Keratin, type I cuticular Ha8
Alias:
Hair keratin, type I Ha8;Keratin-38
Type:
Mass (Da):
50480
Number AA:
456
UniProt ID:
O76015
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T2
_
_
_
_
_
_
M
T
S
S
Y
S
S
S
S
Site 2
S3
_
_
_
_
_
M
T
S
S
Y
S
S
S
S
C
Site 3
S6
_
_
M
T
S
S
Y
S
S
S
S
C
P
L
G
Site 4
S7
_
M
T
S
S
Y
S
S
S
S
C
P
L
G
C
Site 5
S8
M
T
S
S
Y
S
S
S
S
C
P
L
G
C
T
Site 6
S9
T
S
S
Y
S
S
S
S
C
P
L
G
C
T
M
Site 7
T15
S
S
C
P
L
G
C
T
M
A
P
G
A
R
N
Site 8
S26
G
A
R
N
V
S
V
S
P
I
D
I
G
C
Q
Site 9
S59
A
N
R
V
R
V
G
S
T
P
L
G
R
P
S
Site 10
T60
N
R
V
R
V
G
S
T
P
L
G
R
P
S
L
Site 11
S66
S
T
P
L
G
R
P
S
L
C
L
P
P
T
C
Site 12
Y95
N
I
G
I
C
G
A
Y
G
E
N
T
L
N
G
Site 13
Y118
L
N
D
R
L
A
N
Y
L
E
K
V
R
Q
L
Site 14
T135
E
N
A
E
L
E
A
T
L
L
E
R
S
K
C
Site 15
S140
E
A
T
L
L
E
R
S
K
C
H
E
S
T
V
Site 16
T146
R
S
K
C
H
E
S
T
V
C
P
D
Y
Q
S
Site 17
Y151
E
S
T
V
C
P
D
Y
Q
S
Y
F
H
T
I
Site 18
Y154
V
C
P
D
Y
Q
S
Y
F
H
T
I
E
E
L
Site 19
T157
D
Y
Q
S
Y
F
H
T
I
E
E
L
Q
Q
K
Site 20
S195
D
F
R
I
K
L
E
S
E
R
S
L
R
Q
L
Site 21
S198
I
K
L
E
S
E
R
S
L
R
Q
L
V
E
A
Site 22
T218
Q
K
L
L
D
D
A
T
L
A
K
A
D
L
E
Site 23
S237
S
L
K
E
E
Q
L
S
L
K
S
N
H
E
Q
Site 24
S240
E
E
Q
L
S
L
K
S
N
H
E
Q
E
V
K
Site 25
S251
Q
E
V
K
I
L
R
S
Q
L
G
E
K
L
R
Site 26
Y280
L
G
E
M
R
A
Q
Y
E
A
M
L
E
T
N
Site 27
S299
E
Q
W
F
Q
A
Q
S
E
G
I
S
L
Q
D
Site 28
S303
Q
A
Q
S
E
G
I
S
L
Q
D
M
S
C
S
Site 29
S308
G
I
S
L
Q
D
M
S
C
S
E
E
L
Q
C
Site 30
S318
E
E
L
Q
C
C
Q
S
E
I
L
E
L
R
C
Site 31
T339
V
E
R
Q
A
Q
H
T
L
K
D
C
L
Q
N
Site 32
S347
L
K
D
C
L
Q
N
S
L
C
E
A
E
D
R
Site 33
T357
E
A
E
D
R
F
G
T
E
L
A
Q
M
Q
S
Site 34
S364
T
E
L
A
Q
M
Q
S
L
I
S
N
V
E
E
Site 35
S374
S
N
V
E
E
Q
L
S
E
I
R
A
D
L
E
Site 36
Y387
L
E
R
Q
N
Q
E
Y
Q
V
L
L
D
V
K
Site 37
T395
Q
V
L
L
D
V
K
T
R
L
E
N
E
I
A
Site 38
T403
R
L
E
N
E
I
A
T
Y
R
N
L
L
E
S
Site 39
Y404
L
E
N
E
I
A
T
Y
R
N
L
L
E
S
E
Site 40
S410
T
Y
R
N
L
L
E
S
E
D
C
K
L
P
C
Site 41
S421
K
L
P
C
N
P
C
S
T
S
P
S
C
V
T
Site 42
S423
P
C
N
P
C
S
T
S
P
S
C
V
T
A
P
Site 43
T441
R
P
S
C
G
P
C
T
T
C
G
P
T
C
G
Site 44
S450
C
G
P
T
C
G
A
S
T
T
G
S
R
F
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation