PhosphoNET

           
Protein Info 
   
Short Name:  CLPX
Full Name:  ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial
Alias:  ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial; ClpX caseinolytic peptidase X; ClpX caseinolytic protease X; Energy-dependent regulato
Type:  Mitochondrial
Mass (Da):  69224
Number AA:  633
UniProt ID:  O76031
International Prot ID:  IPI00008728
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0009841  GO:0005743  GO:0042645 Uniprot OncoNet
Molecular Function:  GO:0005524  GO:0016887  GO:0016504 PhosphoSite+ KinaseNET
Biological Process:  GO:0006457  GO:0051603   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S29ASAQRGISGGRIHMS
Site 2S36SGGRIHMSVLGRLGT
Site 3S56LQRAPLRSFTETPAY
Site 4T58RAPLRSFTETPAYFA
Site 5T60PLRSFTETPAYFASK
Site 6Y63SFTETPAYFASKDGI
Site 7S66ETPAYFASKDGISKD
Site 8S71FASKDGISKDGSGDG
Site 9S75DGISKDGSGDGNKKS
Site 10S82SGDGNKKSASEGSSK
Site 11S84DGNKKSASEGSSKKS
Site 12S87KKSASEGSSKKSGSG
Site 13S88KSASEGSSKKSGSGN
Site 14S91SEGSSKKSGSGNSGK
Site 15S93GSSKKSGSGNSGKGG
Site 16T117DLCTHVETFVSSTRF
Site 17S120THVETFVSSTRFVKC
Site 18S121HVETFVSSTRFVKCE
Site 19S138HHFFVVLSEADSKKS
Site 20S142VVLSEADSKKSIIKE
Site 21S145SEADSKKSIIKEPES
Site 22S152SIIKEPESAAEAVKL
Site 23Y175PPKKIYNYLDKYVVG
Site 24S184DKYVVGQSFAKKVLS
Site 25Y195KVLSVAVYNHYKRIY
Site 26Y198SVAVYNHYKRIYNNI
Site 27Y202YNHYKRIYNNIPANL
Site 28S220AEVEKQTSLTPRELE
Site 29T222VEKQTSLTPRELEIR
Site 30Y235IRRREDEYRFTKLLQ
Site 31T238REDEYRFTKLLQIAG
Site 32S277RGGEVLDSSHDDIKL
Site 33S278GGEVLDSSHDDIKLE
Site 34S287DDIKLEKSNILLLGP
Site 35Y327TTLTQAGYVGEDIES
Site 36Y345KLLQDANYNVEKAQQ
Site 37S365DEVDKIGSVPGIHQL
Site 38T407SRKLRGETVQVDTTN
Site 39S431NGLDRIISRRKNEKY
Site 40Y438SRRKNEKYLGFGTPS
Site 41T443EKYLGFGTPSNLGKG
Site 42S445YLGFGTPSNLGKGRR
Site 43S463AADLANRSGESNTHQ
Site 44T513LHSLDEKTLVQILTE
Site 45Y529RNAVIPQYQALFSMD
Site 46T543DKCELNVTEDALKAI
Site 47T559RLALERKTGARGLRS
Site 48Y602EGKKEPGYIRAPTKE
Site 49T607PGYIRAPTKESSEEE
Site 50S610IRAPTKESSEEEYDS
Site 51S611RAPTKESSEEEYDSG
Site 52Y615KESSEEEYDSGVEEE
Site 53S617SSEEEYDSGVEEEGW
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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