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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RGS20
Full Name:
Regulator of G-protein signaling 20
Alias:
GAP; Gz-selective GTPase-activating protein; Regulator of G protein signalling 20; Regulator of Gz-selective protein signalling; Regulator of Gz-selective protein signalling 1; RGSZ1; Z; ZGAP1
Type:
Membrane protein
Mass (Da):
43692
Number AA:
388
UniProt ID:
O76081
International Prot ID:
IPI00220880
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0031225
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005096
GO:0005515
GO:0004871
PhosphoSite+
KinaseNET
Biological Process:
GO:0009968
GO:0008277
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T23
F
S
R
P
S
I
W
T
Q
F
L
P
L
F
R
Site 2
T36
F
R
A
Q
R
Y
N
T
D
I
H
Q
I
T
E
Site 3
S56
R
A
V
P
D
I
K
S
F
P
P
A
Q
L
P
Site 4
S65
P
P
A
Q
L
P
D
S
P
A
A
P
K
L
F
Site 5
S87
S
S
L
A
R
F
F
S
H
L
L
R
R
P
P
Site 6
S105
P
R
R
R
L
D
F
S
P
L
L
P
A
L
P
Site 7
S117
A
L
P
A
A
R
L
S
R
G
H
E
E
L
P
Site 8
S142
L
A
L
P
G
R
P
S
G
G
R
P
L
R
P
Site 9
T162
K
P
R
E
E
D
A
T
A
G
Q
S
S
P
M
Site 10
S167
D
A
T
A
G
Q
S
S
P
M
P
Q
M
G
S
Site 11
S174
S
P
M
P
Q
M
G
S
E
R
M
E
M
R
K
Site 12
T190
Q
M
P
A
A
Q
D
T
P
G
A
A
P
G
Q
Site 13
S202
P
G
Q
P
G
A
G
S
R
G
S
N
A
C
C
Site 14
T232
N
Q
E
D
Q
R
P
T
I
A
S
H
E
L
R
Site 15
S235
D
Q
R
P
T
I
A
S
H
E
L
R
A
D
L
Site 16
T244
E
L
R
A
D
L
P
T
W
E
E
S
P
A
P
Site 17
S248
D
L
P
T
W
E
E
S
P
A
P
T
L
E
E
Site 18
T252
W
E
E
S
P
A
P
T
L
E
E
V
N
A
W
Site 19
T269
S
F
D
K
L
M
V
T
P
A
G
R
N
A
F
Site 20
T282
A
F
R
E
F
L
R
T
E
F
S
E
E
N
M
Site 21
Y315
E
E
K
A
R
I
I
Y
E
D
Y
I
S
I
L
Site 22
S323
E
D
Y
I
S
I
L
S
P
K
E
V
S
L
D
Site 23
S328
I
L
S
P
K
E
V
S
L
D
S
R
V
R
E
Site 24
S331
P
K
E
V
S
L
D
S
R
V
R
E
V
I
N
Site 25
Y357
D
D
A
Q
L
Q
I
Y
T
L
M
H
R
D
S
Site 26
Y365
T
L
M
H
R
D
S
Y
P
R
F
M
N
S
A
Site 27
Y374
R
F
M
N
S
A
V
Y
K
D
L
L
Q
S
L
Site 28
S380
V
Y
K
D
L
L
Q
S
L
S
E
K
S
I
E
Site 29
S382
K
D
L
L
Q
S
L
S
E
K
S
I
E
A
_
Site 30
S385
L
Q
S
L
S
E
K
S
I
E
A
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation