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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SRP72
Full Name:
Signal recognition particle 72 kDa protein
Alias:
signal recognition particle 72 kDa; signal recognition particle 72kDa
Type:
Signal recognition protein, targeting
Mass (Da):
74606
Number AA:
671
UniProt ID:
O76094
International Prot ID:
IPI00215888
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005786
GO:0005786
GO:0030529
Uniprot
OncoNet
Molecular Function:
GO:0008312
GO:0005047
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0006614
GO:0042493
GO:0006613
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
S
G
G
S
G
G
V
S
V
P
A
L
W
S
E
Site 2
Y21
L
W
S
E
V
N
R
Y
G
Q
N
G
D
F
T
Site 3
T28
Y
G
Q
N
G
D
F
T
R
A
L
K
T
V
N
Site 4
T46
Q
I
N
K
D
D
V
T
A
L
H
C
K
V
V
Site 5
S79
T
K
V
L
A
N
N
S
L
S
F
E
K
A
Y
Site 6
S81
V
L
A
N
N
S
L
S
F
E
K
A
Y
C
E
Site 7
Y86
S
L
S
F
E
K
A
Y
C
E
Y
R
L
N
R
Site 8
T108
I
E
S
A
N
Q
Q
T
D
K
L
K
E
L
Y
Site 9
Y115
T
D
K
L
K
E
L
Y
G
Q
V
L
Y
R
L
Site 10
S139
Y
R
D
L
V
R
N
S
Q
D
D
Y
D
E
E
Site 11
Y143
V
R
N
S
Q
D
D
Y
D
E
E
R
K
T
N
Site 12
T149
D
Y
D
E
E
R
K
T
N
L
S
A
V
V
A
Site 13
S152
E
E
R
K
T
N
L
S
A
V
V
A
A
Q
S
Site 14
S209
A
E
D
L
C
R
R
S
L
S
E
D
T
D
G
Site 15
S211
D
L
C
R
R
S
L
S
E
D
T
D
G
T
E
Site 16
Y249
T
E
E
A
L
Q
L
Y
N
Q
I
I
K
L
K
Site 17
S299
E
G
V
E
F
K
L
S
K
K
Q
L
Q
A
I
Site 18
S327
A
E
Q
C
R
K
I
S
A
S
L
Q
S
Q
S
Site 19
S329
Q
C
R
K
I
S
A
S
L
Q
S
Q
S
P
E
Site 20
S332
K
I
S
A
S
L
Q
S
Q
S
P
E
H
L
L
Site 21
S334
S
A
S
L
Q
S
Q
S
P
E
H
L
L
P
V
Site 22
T355
L
C
R
E
K
Q
H
T
K
A
I
E
L
L
Q
Site 23
S365
I
E
L
L
Q
E
F
S
D
Q
H
P
E
N
A
Site 24
S385
T
M
A
Q
L
K
I
S
Q
G
N
I
S
K
A
Site 25
S398
K
A
C
L
I
L
R
S
I
E
E
L
K
H
K
Site 26
S410
K
H
K
P
G
M
V
S
A
L
V
T
M
Y
S
Site 27
T414
G
M
V
S
A
L
V
T
M
Y
S
H
E
E
D
Site 28
S417
S
A
L
V
T
M
Y
S
H
E
E
D
I
D
S
Site 29
S424
S
H
E
E
D
I
D
S
A
I
E
V
F
T
Q
Site 30
S443
Y
Q
N
H
Q
P
K
S
P
A
H
L
S
L
I
Site 31
S448
P
K
S
P
A
H
L
S
L
I
R
E
A
A
N
Site 32
Y460
A
A
N
F
K
L
K
Y
G
R
K
K
E
A
I
Site 33
T483
Q
N
P
K
D
I
H
T
L
A
Q
L
I
S
A
Site 34
S503
P
E
K
A
K
A
L
S
K
H
L
P
S
S
D
Site 35
S508
A
L
S
K
H
L
P
S
S
D
S
M
S
L
K
Site 36
S509
L
S
K
H
L
P
S
S
D
S
M
S
L
K
V
Site 37
S511
K
H
L
P
S
S
D
S
M
S
L
K
V
D
V
Site 38
S513
L
P
S
S
D
S
M
S
L
K
V
D
V
E
A
Site 39
T528
L
E
N
S
A
G
A
T
Y
I
R
K
K
G
G
Site 40
Y529
E
N
S
A
G
A
T
Y
I
R
K
K
G
G
K
Site 41
S541
G
G
K
V
T
G
D
S
Q
P
K
E
Q
G
Q
Site 42
Y566
K
G
K
L
P
K
N
Y
D
P
K
V
T
P
D
Site 43
T571
K
N
Y
D
P
K
V
T
P
D
P
E
R
W
L
Site 44
S584
W
L
P
M
R
E
R
S
Y
Y
R
G
R
K
K
Site 45
Y585
L
P
M
R
E
R
S
Y
Y
R
G
R
K
K
G
Site 46
Y586
P
M
R
E
R
S
Y
Y
R
G
R
K
K
G
K
Site 47
S610
Q
G
A
T
A
G
A
S
S
E
L
D
A
S
K
Site 48
S616
A
S
S
E
L
D
A
S
K
T
V
S
S
P
P
Site 49
T618
S
E
L
D
A
S
K
T
V
S
S
P
P
T
S
Site 50
S620
L
D
A
S
K
T
V
S
S
P
P
T
S
P
R
Site 51
S621
D
A
S
K
T
V
S
S
P
P
T
S
P
R
P
Site 52
T624
K
T
V
S
S
P
P
T
S
P
R
P
G
S
A
Site 53
S625
T
V
S
S
P
P
T
S
P
R
P
G
S
A
A
Site 54
S630
P
T
S
P
R
P
G
S
A
A
T
V
S
A
S
Site 55
T633
P
R
P
G
S
A
A
T
V
S
A
S
T
S
N
Site 56
S635
P
G
S
A
A
T
V
S
A
S
T
S
N
I
I
Site 57
S637
S
A
A
T
V
S
A
S
T
S
N
I
I
P
P
Site 58
T638
A
A
T
V
S
A
S
T
S
N
I
I
P
P
R
Site 59
S639
A
T
V
S
A
S
T
S
N
I
I
P
P
R
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation