KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
DRAK2
Full Name:
Serine/threonine-protein kinase 17B
Alias:
EC 2.7.11.1; Serine,threonine kinase 17B; ST17B; STK17B
Type:
Protein-serine kinase, CAMK group, DAPK family
Mass (Da):
42344
Number AA:
372
UniProt ID:
O94768
International Prot ID:
IPI00014934
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0004674
PhosphoSite+
KinaseNET
Biological Process:
GO:0006915
GO:0006917
GO:0006468
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
R
R
R
F
D
C
R
S
I
S
G
L
L
T
T
Site 2
S12
R
F
D
C
R
S
I
S
G
L
L
T
T
T
P
Site 3
S54
V
R
Q
C
I
S
K
S
T
G
Q
E
Y
A
A
Site 4
Y59
S
K
S
T
G
Q
E
Y
A
A
K
F
L
K
K
Site 5
S131
P
E
L
A
E
M
V
S
E
N
D
V
I
R
L
Site 6
S167
K
P
Q
N
I
L
L
S
S
I
Y
P
L
G
D
Site 7
T198
E
L
R
E
I
M
G
T
P
E
Y
L
A
P
E
Site 8
S233
Y
M
L
L
T
H
T
S
P
F
V
G
E
D
N
Site 9
Y244
G
E
D
N
Q
E
T
Y
L
N
I
S
Q
V
N
Site 10
S248
Q
E
T
Y
L
N
I
S
Q
V
N
V
D
Y
S
Site 11
Y254
I
S
Q
V
N
V
D
Y
S
E
E
T
F
S
S
Site 12
S255
S
Q
V
N
V
D
Y
S
E
E
T
F
S
S
V
Site 13
T258
N
V
D
Y
S
E
E
T
F
S
S
V
S
Q
L
Site 14
S260
D
Y
S
E
E
T
F
S
S
V
S
Q
L
A
T
Site 15
S261
Y
S
E
E
T
F
S
S
V
S
Q
L
A
T
D
Site 16
T283
K
N
P
E
K
R
P
T
A
E
I
C
L
S
H
Site 17
S308
L
F
H
P
E
E
T
S
S
S
S
Q
T
Q
D
Site 18
S309
F
H
P
E
E
T
S
S
S
S
Q
T
Q
D
H
Site 19
S310
H
P
E
E
T
S
S
S
S
Q
T
Q
D
H
S
Site 20
S311
P
E
E
T
S
S
S
S
Q
T
Q
D
H
S
V
Site 21
T313
E
T
S
S
S
S
Q
T
Q
D
H
S
V
R
S
Site 22
S317
S
S
Q
T
Q
D
H
S
V
R
S
S
E
D
K
Site 23
S321
Q
D
H
S
V
R
S
S
E
D
K
T
S
K
S
Site 24
T325
V
R
S
S
E
D
K
T
S
K
S
S
C
N
G
Site 25
S326
R
S
S
E
D
K
T
S
K
S
S
C
N
G
T
Site 26
S328
S
E
D
K
T
S
K
S
S
C
N
G
T
C
G
Site 27
T333
S
K
S
S
C
N
G
T
C
G
D
R
E
D
K
Site 28
S347
K
E
N
I
P
E
D
S
S
M
V
S
K
R
F
Site 29
S348
E
N
I
P
E
D
S
S
M
V
S
K
R
F
R
Site 30
S351
P
E
D
S
S
M
V
S
K
R
F
R
F
D
D
Site 31
S359
K
R
F
R
F
D
D
S
L
P
N
P
H
E
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation