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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ECM2
Full Name:
Extracellular matrix protein 2
Alias:
Extracellular matrix protein 2, female organ and adipocyte specific; Matrix glycoprotein SC1/ECM2
Type:
Adhesion
Mass (Da):
79789
Number AA:
699
UniProt ID:
O94769
International Prot ID:
IPI00015315
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005578
Uniprot
OncoNet
Molecular Function:
GO:0005178
PhosphoSite+
KinaseNET
Biological Process:
GO:0007160
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y34
R
K
Q
R
R
K
I
Y
H
R
R
L
R
K
S
Site 2
S41
Y
H
R
R
L
R
K
S
S
T
S
H
K
H
R
Site 3
S42
H
R
R
L
R
K
S
S
T
S
H
K
H
R
S
Site 4
T43
R
R
L
R
K
S
S
T
S
H
K
H
R
S
N
Site 5
S44
R
L
R
K
S
S
T
S
H
K
H
R
S
N
R
Site 6
S49
S
T
S
H
K
H
R
S
N
R
Q
L
G
I
Q
Site 7
Y74
L
P
I
V
N
F
D
Y
S
M
E
E
K
F
E
Site 8
S75
P
I
V
N
F
D
Y
S
M
E
E
K
F
E
S
Site 9
S82
S
M
E
E
K
F
E
S
F
S
S
F
P
G
V
Site 10
S84
E
E
K
F
E
S
F
S
S
F
P
G
V
E
S
Site 11
S85
E
K
F
E
S
F
S
S
F
P
G
V
E
S
S
Site 12
S91
S
S
F
P
G
V
E
S
S
Y
N
V
L
P
G
Site 13
S92
S
F
P
G
V
E
S
S
Y
N
V
L
P
G
K
Site 14
Y93
F
P
G
V
E
S
S
Y
N
V
L
P
G
K
K
Site 15
T146
H
P
Q
R
C
P
Q
T
V
I
P
E
G
E
C
Site 16
S178
L
N
D
R
N
E
F
S
G
D
S
S
E
Q
R
Site 17
S182
N
E
F
S
G
D
S
S
E
Q
R
E
P
T
N
Site 18
T188
S
S
E
Q
R
E
P
T
N
L
L
H
K
Q
L
Site 19
S213
V
R
K
E
A
L
Q
S
E
E
D
E
E
V
K
Site 20
T230
D
T
E
Q
K
R
E
T
P
E
S
R
N
Q
G
Site 21
S233
Q
K
R
E
T
P
E
S
R
N
Q
G
Q
L
Y
Site 22
Y240
S
R
N
Q
G
Q
L
Y
S
E
G
D
S
R
G
Site 23
S241
R
N
Q
G
Q
L
Y
S
E
G
D
S
R
G
G
Site 24
S245
Q
L
Y
S
E
G
D
S
R
G
G
D
R
K
Q
Site 25
S302
G
D
M
F
R
M
P
S
R
S
P
L
P
A
P
Site 26
S304
M
F
R
M
P
S
R
S
P
L
P
A
P
P
R
Site 27
T313
L
P
A
P
P
R
G
T
L
R
L
P
S
G
C
Site 28
S318
R
G
T
L
R
L
P
S
G
C
S
L
S
Y
R
Site 29
S321
L
R
L
P
S
G
C
S
L
S
Y
R
T
I
S
Site 30
Y324
P
S
G
C
S
L
S
Y
R
T
I
S
C
I
N
Site 31
S347
L
T
A
P
Q
I
T
S
L
E
L
T
G
N
S
Site 32
S375
N
L
E
R
L
D
L
S
K
N
N
I
T
S
S
Site 33
S382
S
K
N
N
I
T
S
S
G
I
G
P
K
A
F
Site 34
S410
N
N
L
I
Q
I
P
S
Q
L
P
S
T
L
E
Site 35
S414
Q
I
P
S
Q
L
P
S
T
L
E
E
L
K
V
Site 36
T415
I
P
S
Q
L
P
S
T
L
E
E
L
K
V
N
Site 37
S433
L
Q
A
I
D
E
E
S
L
S
D
L
N
Q
L
Site 38
S435
A
I
D
E
E
S
L
S
D
L
N
Q
L
V
T
Site 39
T442
S
D
L
N
Q
L
V
T
L
E
L
E
G
N
N
Site 40
S451
E
L
E
G
N
N
L
S
E
A
N
V
N
P
L
Site 41
Y468
K
P
L
K
S
L
A
Y
L
R
L
G
K
N
K
Site 42
S486
I
P
Q
G
L
P
G
S
I
E
E
L
Y
L
E
Site 43
Y491
P
G
S
I
E
E
L
Y
L
E
N
N
Q
I
E
Site 44
S539
I
N
Q
E
N
L
E
S
I
D
L
S
Y
N
K
Site 45
S543
N
L
E
S
I
D
L
S
Y
N
K
L
Y
H
V
Site 46
Y544
L
E
S
I
D
L
S
Y
N
K
L
Y
H
V
P
Site 47
Y548
D
L
S
Y
N
K
L
Y
H
V
P
S
Y
L
P
Site 48
S552
N
K
L
Y
H
V
P
S
Y
L
P
K
S
L
L
Site 49
Y553
K
L
Y
H
V
P
S
Y
L
P
K
S
L
L
H
Site 50
Y574
Q
I
E
R
I
P
G
Y
V
F
G
H
M
E
P
Site 51
Y585
H
M
E
P
G
L
E
Y
L
Y
L
S
F
N
K
Site 52
Y587
E
P
G
L
E
Y
L
Y
L
S
F
N
K
L
A
Site 53
S589
G
L
E
Y
L
Y
L
S
F
N
K
L
A
D
D
Site 54
S602
D
D
G
M
D
R
V
S
F
Y
G
A
Y
H
S
Site 55
Y604
G
M
D
R
V
S
F
Y
G
A
Y
H
S
L
R
Site 56
Y607
R
V
S
F
Y
G
A
Y
H
S
L
R
E
L
F
Site 57
S609
S
F
Y
G
A
Y
H
S
L
R
E
L
F
L
D
Site 58
S622
L
D
H
N
D
L
K
S
I
P
P
G
I
Q
E
Site 59
S660
N
A
E
E
D
D
D
S
N
L
E
H
L
H
L
Site 60
S679
I
K
I
R
E
I
P
S
Y
T
F
S
C
I
R
Site 61
Y680
K
I
R
E
I
P
S
Y
T
F
S
C
I
R
S
Site 62
T681
I
R
E
I
P
S
Y
T
F
S
C
I
R
S
Y
Site 63
S683
E
I
P
S
Y
T
F
S
C
I
R
S
Y
S
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation