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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MTA2
Full Name:
Metastasis-associated protein MTA2
Alias:
Metastasis associated 1 family, member 2; Metastasis associated protein MTA2; Metastasis-associated 1-like 1; MTA1L1; MTA1-L1; MTA1-L1 protein; P53 target protein in deacetylase complex
Type:
Nuclear receptor co-regulator; Transcription factor
Mass (Da):
75023
Number AA:
668
UniProt ID:
O94776
International Prot ID:
IPI00171798
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016581
GO:0005634
GO:0005730
Uniprot
OncoNet
Molecular Function:
GO:0043565
GO:0003700
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006333
GO:0006325
GO:0006333
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y11
N
M
Y
R
V
G
D
Y
V
Y
F
E
N
S
S
Site 2
Y13
Y
R
V
G
D
Y
V
Y
F
E
N
S
S
S
N
Site 3
S19
V
Y
F
E
N
S
S
S
N
P
Y
L
V
R
R
Site 4
Y22
E
N
S
S
S
N
P
Y
L
V
R
R
I
E
E
Site 5
T33
R
I
E
E
L
N
K
T
A
N
G
N
V
E
A
Site 6
S52
L
F
R
R
R
D
I
S
S
S
L
N
S
L
A
Site 7
S53
F
R
R
R
D
I
S
S
S
L
N
S
L
A
D
Site 8
S54
R
R
R
D
I
S
S
S
L
N
S
L
A
D
S
Site 9
S57
D
I
S
S
S
L
N
S
L
A
D
S
N
A
R
Site 10
S61
S
L
N
S
L
A
D
S
N
A
R
E
F
E
E
Site 11
S91
K
H
R
E
L
F
L
S
R
Q
F
E
S
L
P
Site 12
T100
Q
F
E
S
L
P
A
T
H
I
R
G
K
C
S
Site 13
S118
L
N
E
T
D
I
L
S
Q
Y
L
E
K
E
D
Site 14
Y120
E
T
D
I
L
S
Q
Y
L
E
K
E
D
C
F
Site 15
Y153
E
I
R
V
G
C
K
Y
Q
A
E
I
P
D
R
Site 16
S166
D
R
L
V
E
G
E
S
D
N
R
N
Q
Q
K
Site 17
S210
F
A
R
A
L
D
C
S
S
S
I
R
Q
P
S
Site 18
S211
A
R
A
L
D
C
S
S
S
I
R
Q
P
S
L
Site 19
S212
R
A
L
D
C
S
S
S
I
R
Q
P
S
L
H
Site 20
S217
S
S
S
I
R
Q
P
S
L
H
M
S
A
A
A
Site 21
S221
R
Q
P
S
L
H
M
S
A
A
A
A
S
R
D
Site 22
T237
T
L
F
H
A
M
D
T
L
Q
R
N
G
Y
D
Site 23
Y243
D
T
L
Q
R
N
G
Y
D
L
A
K
A
M
S
Site 24
S250
Y
D
L
A
K
A
M
S
T
L
V
P
Q
G
G
Site 25
T251
D
L
A
K
A
M
S
T
L
V
P
Q
G
G
P
Site 26
S271
E
M
E
E
W
S
A
S
E
A
M
L
F
E
E
Site 27
Y283
F
E
E
A
L
E
K
Y
G
K
D
F
N
D
I
Site 28
Y316
M
W
K
T
T
D
R
Y
I
Q
Q
K
R
L
K
Site 29
Y335
D
S
K
L
K
Q
V
Y
I
P
T
Y
T
K
P
Site 30
Y339
K
Q
V
Y
I
P
T
Y
T
K
P
N
P
N
Q
Site 31
S349
P
N
P
N
Q
I
I
S
V
G
S
K
P
G
M
Site 32
T366
A
G
F
Q
K
G
L
T
C
E
S
C
H
T
T
Site 33
T406
K
K
Y
G
G
L
K
T
P
T
Q
L
E
G
A
Site 34
T417
L
E
G
A
T
R
G
T
T
E
P
H
S
R
G
Site 35
T418
E
G
A
T
R
G
T
T
E
P
H
S
R
G
H
Site 36
S422
R
G
T
T
E
P
H
S
R
G
H
L
S
R
P
Site 37
S427
P
H
S
R
G
H
L
S
R
P
E
A
Q
S
L
Site 38
S433
L
S
R
P
E
A
Q
S
L
S
P
Y
T
T
S
Site 39
S435
R
P
E
A
Q
S
L
S
P
Y
T
T
S
A
N
Site 40
Y437
E
A
Q
S
L
S
P
Y
T
T
S
A
N
R
A
Site 41
T438
A
Q
S
L
S
P
Y
T
T
S
A
N
R
A
K
Site 42
T439
Q
S
L
S
P
Y
T
T
S
A
N
R
A
K
L
Site 43
S440
S
L
S
P
Y
T
T
S
A
N
R
A
K
L
L
Site 44
T453
L
L
A
K
N
R
Q
T
F
L
L
Q
T
T
K
Site 45
Y483
R
R
A
A
R
R
P
Y
A
P
I
N
A
N
A
Site 46
S496
N
A
I
K
A
E
C
S
I
R
L
P
K
A
A
Site 47
T505
R
L
P
K
A
A
K
T
P
L
K
I
H
P
L
Site 48
T519
L
V
R
L
P
L
A
T
I
V
K
D
L
V
A
Site 49
T534
Q
A
P
L
K
P
K
T
P
R
G
T
K
T
P
Site 50
T538
K
P
K
T
P
R
G
T
K
T
P
I
N
R
N
Site 51
T540
K
T
P
R
G
T
K
T
P
I
N
R
N
Q
L
Site 52
S548
P
I
N
R
N
Q
L
S
Q
N
R
G
L
G
G
Site 53
S581
A
N
G
R
P
L
A
S
G
I
R
S
S
S
Q
Site 54
S585
P
L
A
S
G
I
R
S
S
S
Q
P
A
A
K
Site 55
S586
L
A
S
G
I
R
S
S
S
Q
P
A
A
K
R
Site 56
S587
A
S
G
I
R
S
S
S
Q
P
A
A
K
R
Q
Site 57
S655
P
V
P
L
P
A
P
S
H
P
A
S
T
N
E
Site 58
S659
P
A
P
S
H
P
A
S
T
N
E
P
I
V
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation