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Updated November 2019
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Protein Info
Short Name:
CNTN5
Full Name:
Contactin-5
Alias:
Neural recognition molecule NB-2
Type:
Mass (Da):
120686
Number AA:
1100
UniProt ID:
O94779
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S21
T
M
C
L
S
E
Y
S
K
S
L
P
G
L
S
Site 2
S23
C
L
S
E
Y
S
K
S
L
P
G
L
S
T
S
Site 3
S40
A
L
L
R
I
K
K
S
S
S
S
S
L
F
G
Site 4
S41
L
L
R
I
K
K
S
S
S
S
S
L
F
G
S
Site 5
S42
L
R
I
K
K
S
S
S
S
S
L
F
G
S
K
Site 6
S43
R
I
K
K
S
S
S
S
S
L
F
G
S
K
T
Site 7
S44
I
K
K
S
S
S
S
S
L
F
G
S
K
T
R
Site 8
S48
S
S
S
S
L
F
G
S
K
T
R
P
R
Y
S
Site 9
T50
S
S
L
F
G
S
K
T
R
P
R
Y
S
S
P
Site 10
Y54
G
S
K
T
R
P
R
Y
S
S
P
S
L
G
T
Site 11
S55
S
K
T
R
P
R
Y
S
S
P
S
L
G
T
L
Site 12
S56
K
T
R
P
R
Y
S
S
P
S
L
G
T
L
S
Site 13
S58
R
P
R
Y
S
S
P
S
L
G
T
L
S
A
S
Site 14
T61
Y
S
S
P
S
L
G
T
L
S
A
S
S
P
S
Site 15
S63
S
P
S
L
G
T
L
S
A
S
S
P
S
W
L
Site 16
Y76
W
L
G
A
A
Q
N
Y
Y
S
P
I
N
L
Y
Site 17
Y77
L
G
A
A
Q
N
Y
Y
S
P
I
N
L
Y
H
Site 18
S78
G
A
A
Q
N
Y
Y
S
P
I
N
L
Y
H
S
Site 19
Y83
Y
Y
S
P
I
N
L
Y
H
S
S
D
A
F
K
Site 20
S85
S
P
I
N
L
Y
H
S
S
D
A
F
K
Q
D
Site 21
S86
P
I
N
L
Y
H
S
S
D
A
F
K
Q
D
E
Site 22
S94
D
A
F
K
Q
D
E
S
V
D
Y
G
P
V
F
Site 23
Y97
K
Q
D
E
S
V
D
Y
G
P
V
F
V
Q
E
Site 24
T112
P
D
D
I
I
F
P
T
D
S
D
E
K
K
V
Site 25
S114
D
I
I
F
P
T
D
S
D
E
K
K
V
A
L
Site 26
S132
V
R
G
N
P
V
P
S
Y
R
W
L
R
N
G
Site 27
Y133
R
G
N
P
V
P
S
Y
R
W
L
R
N
G
T
Site 28
T140
Y
R
W
L
R
N
G
T
E
I
D
L
E
S
D
Site 29
S146
G
T
E
I
D
L
E
S
D
Y
R
Y
S
L
I
Site 30
Y148
E
I
D
L
E
S
D
Y
R
Y
S
L
I
D
G
Site 31
Y150
D
L
E
S
D
Y
R
Y
S
L
I
D
G
T
F
Site 32
S151
L
E
S
D
Y
R
Y
S
L
I
D
G
T
F
I
Site 33
T156
R
Y
S
L
I
D
G
T
F
I
I
S
N
P
S
Site 34
S163
T
F
I
I
S
N
P
S
E
A
K
D
S
G
H
Site 35
S168
N
P
S
E
A
K
D
S
G
H
Y
Q
C
L
A
Site 36
Y193
E
A
T
L
Q
F
A
Y
L
G
N
F
S
G
R
Site 37
S198
F
A
Y
L
G
N
F
S
G
R
T
R
S
A
V
Site 38
S203
N
F
S
G
R
T
R
S
A
V
S
V
R
E
G
Site 39
S206
G
R
T
R
S
A
V
S
V
R
E
G
Q
G
V
Site 40
S218
Q
G
V
V
L
M
C
S
P
P
P
H
S
P
E
Site 41
S223
M
C
S
P
P
P
H
S
P
E
I
I
Y
S
W
Site 42
Y228
P
H
S
P
E
I
I
Y
S
W
V
F
N
E
F
Site 43
S237
W
V
F
N
E
F
P
S
F
V
A
E
D
S
R
Site 44
S243
P
S
F
V
A
E
D
S
R
R
F
I
S
Q
E
Site 45
S248
E
D
S
R
R
F
I
S
Q
E
T
G
N
L
Y
Site 46
Y255
S
Q
E
T
G
N
L
Y
I
S
K
V
Q
T
S
Site 47
S257
E
T
G
N
L
Y
I
S
K
V
Q
T
S
D
V
Site 48
S262
Y
I
S
K
V
Q
T
S
D
V
G
S
Y
I
C
Site 49
Y267
Q
T
S
D
V
G
S
Y
I
C
L
V
K
N
T
Site 50
T285
A
R
V
L
S
P
P
T
P
L
T
L
R
N
D
Site 51
T288
L
S
P
P
T
P
L
T
L
R
N
D
G
V
M
Site 52
Y298
N
D
G
V
M
G
E
Y
E
P
K
I
E
V
H
Site 53
S343
K
V
N
G
Y
I
P
S
K
A
R
L
R
K
S
Site 54
S350
S
K
A
R
L
R
K
S
Q
A
V
L
E
I
P
Site 55
Y367
Q
L
D
D
A
G
I
Y
E
C
R
A
E
N
S
Site 56
S379
E
N
S
R
G
K
N
S
F
R
G
Q
L
Q
V
Site 57
Y387
F
R
G
Q
L
Q
V
Y
T
Y
P
H
W
V
E
Site 58
Y389
G
Q
L
Q
V
Y
T
Y
P
H
W
V
E
K
L
Site 59
T399
W
V
E
K
L
N
D
T
Q
L
D
S
G
S
P
Site 60
S403
L
N
D
T
Q
L
D
S
G
S
P
L
R
W
E
Site 61
S405
D
T
Q
L
D
S
G
S
P
L
R
W
E
C
K
Site 62
T414
L
R
W
E
C
K
A
T
G
K
P
R
P
T
Y
Site 63
T420
A
T
G
K
P
R
P
T
Y
R
W
L
K
N
G
Site 64
Y421
T
G
K
P
R
P
T
Y
R
W
L
K
N
G
V
Site 65
S431
L
K
N
G
V
P
L
S
P
Q
S
R
V
E
M
Site 66
S434
G
V
P
L
S
P
Q
S
R
V
E
M
V
N
G
Site 67
Y464
Q
C
L
A
E
N
K
Y
G
A
I
Y
A
S
A
Site 68
Y468
E
N
K
Y
G
A
I
Y
A
S
A
E
L
K
I
Site 69
S508
I
E
C
K
P
Q
G
S
P
K
P
T
I
S
W
Site 70
T512
P
Q
G
S
P
K
P
T
I
S
W
K
K
G
D
Site 71
S514
G
S
P
K
P
T
I
S
W
K
K
G
D
R
A
Site 72
S535
I
A
I
L
P
D
G
S
L
R
I
L
N
A
S
Site 73
S542
S
L
R
I
L
N
A
S
K
S
D
E
G
K
Y
Site 74
S544
R
I
L
N
A
S
K
S
D
E
G
K
Y
V
C
Site 75
Y549
S
K
S
D
E
G
K
Y
V
C
R
G
E
N
V
Site 76
T577
E
P
T
R
I
E
L
T
P
K
R
T
E
L
T
Site 77
T584
T
P
K
R
T
E
L
T
V
G
E
S
I
V
L
Site 78
T604
H
D
A
S
L
D
V
T
F
Y
W
T
L
K
G
Site 79
Y606
A
S
L
D
V
T
F
Y
W
T
L
K
G
Q
P
Site 80
T608
L
D
V
T
F
Y
W
T
L
K
G
Q
P
I
D
Site 81
S625
E
E
G
G
H
F
E
S
I
R
A
Q
A
S
S
Site 82
S631
E
S
I
R
A
Q
A
S
S
A
D
L
M
I
R
Site 83
S632
S
I
R
A
Q
A
S
S
A
D
L
M
I
R
N
Site 84
T654
R
Y
G
C
R
V
Q
T
T
A
D
S
V
S
D
Site 85
S658
R
V
Q
T
T
A
D
S
V
S
D
E
A
E
L
Site 86
S660
Q
T
T
A
D
S
V
S
D
E
A
E
L
L
V
Site 87
S685
I
V
E
E
I
T
E
S
T
A
T
L
S
W
S
Site 88
T688
E
I
T
E
S
T
A
T
L
S
W
S
P
A
A
Site 89
S690
T
E
S
T
A
T
L
S
W
S
P
A
A
D
N
Site 90
S692
S
T
A
T
L
S
W
S
P
A
A
D
N
H
S
Site 91
S699
S
P
A
A
D
N
H
S
P
I
S
S
Y
N
L
Site 92
S702
A
D
N
H
S
P
I
S
S
Y
N
L
Q
A
R
Site 93
S703
D
N
H
S
P
I
S
S
Y
N
L
Q
A
R
S
Site 94
S710
S
Y
N
L
Q
A
R
S
P
F
S
L
G
W
Q
Site 95
S713
L
Q
A
R
S
P
F
S
L
G
W
Q
T
V
K
Site 96
T756
V
A
T
N
P
I
G
T
G
D
P
S
T
P
S
Site 97
S760
P
I
G
T
G
D
P
S
T
P
S
R
M
I
R
Site 98
T761
I
G
T
G
D
P
S
T
P
S
R
M
I
R
T
Site 99
T775
T
N
E
A
V
P
K
T
A
P
T
N
V
S
G
Site 100
S781
K
T
A
P
T
N
V
S
G
R
S
G
R
R
H
Site 101
S784
P
T
N
V
S
G
R
S
G
R
R
H
E
L
V
Site 102
Y809
Q
N
G
E
G
F
G
Y
I
V
A
F
R
P
N
Site 103
T827
G
W
K
E
K
M
V
T
S
S
E
A
S
K
F
Site 104
S828
W
K
E
K
M
V
T
S
S
E
A
S
K
F
I
Site 105
S829
K
E
K
M
V
T
S
S
E
A
S
K
F
I
Y
Site 106
S832
M
V
T
S
S
E
A
S
K
F
I
Y
R
D
E
Site 107
Y836
S
E
A
S
K
F
I
Y
R
D
E
S
V
P
P
Site 108
S840
K
F
I
Y
R
D
E
S
V
P
P
L
T
P
F
Site 109
T845
D
E
S
V
P
P
L
T
P
F
E
V
K
V
G
Site 110
Y854
F
E
V
K
V
G
V
Y
N
N
K
G
D
G
P
Site 111
S876
C
S
A
E
G
E
P
S
A
A
P
T
D
V
K
Site 112
T880
G
E
P
S
A
A
P
T
D
V
K
A
T
S
V
Site 113
S902
A
W
K
H
I
K
E
S
L
G
R
P
Q
G
F
Site 114
Y913
P
Q
G
F
E
V
G
Y
W
K
D
M
E
Q
E
Site 115
T922
K
D
M
E
Q
E
D
T
A
E
T
V
K
T
R
Site 116
T925
E
Q
E
D
T
A
E
T
V
K
T
R
G
N
E
Site 117
T928
D
T
A
E
T
V
K
T
R
G
N
E
S
F
V
Site 118
Y946
G
L
E
G
N
T
L
Y
H
F
T
V
R
A
Y
Site 119
Y953
Y
H
F
T
V
R
A
Y
N
G
A
G
Y
G
P
Site 120
Y958
R
A
Y
N
G
A
G
Y
G
P
P
S
S
E
V
Site 121
S962
G
A
G
Y
G
P
P
S
S
E
V
S
A
T
T
Site 122
S963
A
G
Y
G
P
P
S
S
E
V
S
A
T
T
K
Site 123
S966
G
P
P
S
S
E
V
S
A
T
T
K
K
S
P
Site 124
T968
P
S
S
E
V
S
A
T
T
K
K
S
P
P
S
Site 125
S972
V
S
A
T
T
K
K
S
P
P
S
Q
A
P
S
Site 126
S975
T
T
K
K
S
P
P
S
Q
A
P
S
N
L
R
Site 127
S979
S
P
P
S
Q
A
P
S
N
L
R
W
E
Q
Q
Site 128
S988
L
R
W
E
Q
Q
G
S
Q
V
S
L
G
W
E
Site 129
S991
E
Q
Q
G
S
Q
V
S
L
G
W
E
P
V
I
Site 130
Y1009
N
E
S
E
V
V
G
Y
K
V
F
Y
R
Q
E
Site 131
Y1013
V
V
G
Y
K
V
F
Y
R
Q
E
G
H
S
N
Site 132
S1019
F
Y
R
Q
E
G
H
S
N
S
Q
V
I
E
T
Site 133
S1021
R
Q
E
G
H
S
N
S
Q
V
I
E
T
Q
K
Site 134
Y1048
Y
I
I
E
V
R
A
Y
S
E
G
G
D
G
T
Site 135
S1049
I
I
E
V
R
A
Y
S
E
G
G
D
G
T
A
Site 136
T1055
Y
S
E
G
G
D
G
T
A
S
S
Q
I
R
V
Site 137
S1058
G
G
D
G
T
A
S
S
Q
I
R
V
P
S
Y
Site 138
S1064
S
S
Q
I
R
V
P
S
Y
S
G
G
K
I
T
Site 139
S1066
Q
I
R
V
P
S
Y
S
G
G
K
I
T
S
A
Site 140
T1071
S
Y
S
G
G
K
I
T
S
A
Q
S
T
L
H
Site 141
S1072
Y
S
G
G
K
I
T
S
A
Q
S
T
L
H
S
Site 142
S1075
G
K
I
T
S
A
Q
S
T
L
H
S
L
S
T
Site 143
T1076
K
I
T
S
A
Q
S
T
L
H
S
L
S
T
S
Site 144
S1079
S
A
Q
S
T
L
H
S
L
S
T
S
S
S
S
Site 145
S1081
Q
S
T
L
H
S
L
S
T
S
S
S
S
V
T
Site 146
T1082
S
T
L
H
S
L
S
T
S
S
S
S
V
T
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation