KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ALDH1A2
Full Name:
Retinal dehydrogenase 2
Alias:
AL1A2; Aldehyde dehydrogenase 1 family, member A2; Aldehyde dehydrogenase 1A2; Aldehyde dehydrogenase family 1 member A2; EC 1.2.1.36; II; RALDH; RALDH 2; RALDH(II); RALDH2; RALDH2-T; Retinaldehyde dehydrogenase 2; Retinaldehyde-specific dehydrogenase type 2
Type:
Oxidoreductase, Metabolism of Cofactors and Vitamins group, Retinol metabolism family
Mass (Da):
56724
Number AA:
518
UniProt ID:
O94788
International Prot ID:
IPI00216805
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0004028
GO:0016918
GO:0001758
PhosphoSite+
KinaseNET
Biological Process:
GO:0008285
GO:0021915
GO:0055114
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T30
L
H
L
L
P
S
P
T
P
N
L
E
I
K
Y
Site 2
Y37
T
P
N
L
E
I
K
Y
T
K
I
F
I
N
N
Site 3
Y58
S
G
R
V
F
P
V
Y
N
P
A
T
G
E
Q
Site 4
S89
Q
A
A
R
L
A
F
S
L
G
S
V
W
R
R
Site 5
S92
R
L
A
F
S
L
G
S
V
W
R
R
M
D
A
Site 6
S100
V
W
R
R
M
D
A
S
E
R
G
R
L
L
D
Site 7
T122
R
D
R
A
V
L
A
T
M
E
S
L
N
G
G
Site 8
Y149
G
V
I
K
T
F
R
Y
Y
A
G
W
A
D
K
Site 9
Y150
V
I
K
T
F
R
Y
Y
A
G
W
A
D
K
I
Site 10
Y168
T
I
P
V
D
G
D
Y
F
T
F
T
R
H
E
Site 11
T170
P
V
D
G
D
Y
F
T
F
T
R
H
E
P
I
Site 12
T172
D
G
D
Y
F
T
F
T
R
H
E
P
I
G
V
Site 13
S278
I
Q
E
A
A
G
R
S
N
L
K
R
V
T
L
Site 14
T284
R
S
N
L
K
R
V
T
L
E
L
G
G
K
S
Site 15
Y303
F
A
D
A
D
L
D
Y
A
V
E
Q
A
H
Q
Site 16
S331
S
R
I
F
V
E
E
S
I
Y
E
E
F
V
R
Site 17
Y333
I
F
V
E
E
S
I
Y
E
E
F
V
R
R
S
Site 18
S340
Y
E
E
F
V
R
R
S
V
E
R
A
K
R
R
Site 19
S351
A
K
R
R
V
V
G
S
P
F
D
P
T
T
E
Site 20
T356
V
G
S
P
F
D
P
T
T
E
Q
G
P
Q
I
Site 21
T357
G
S
P
F
D
P
T
T
E
Q
G
P
Q
I
D
Site 22
T430
Q
E
I
L
R
F
K
T
M
D
E
V
I
E
R
Site 23
T459
N
D
I
N
K
A
L
T
V
S
S
A
M
Q
A
Site 24
S481
Y
N
A
L
N
A
Q
S
P
F
G
G
F
K
M
Site 25
S489
P
F
G
G
F
K
M
S
G
N
G
R
E
M
G
Site 26
Y503
G
E
F
G
L
R
E
Y
S
E
V
K
T
V
T
Site 27
S504
E
F
G
L
R
E
Y
S
E
V
K
T
V
T
V
Site 28
T508
R
E
Y
S
E
V
K
T
V
T
V
K
I
P
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation