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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GFAT2
Full Name:
Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 2
Alias:
D-fructose-6- phosphate amidotransferase 2; GFA2; GFAT 2; GFPT2; Glutamine: fructose-6-phosphate aminotransferase 2; Glutamine-fructose-6-phosphate transaminase 2; Hexosephosphate aminotransferase 2
Type:
EC 2.6.1.16; Transferase; Carbohydrate Metabolism - amino sugar and nucleotide sugar; Amino Acid Metabolism - alanine, aspartate and glutamate
Mass (Da):
76931
Number AA:
682
UniProt ID:
O94808
International Prot ID:
IPI00216159
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0004360
GO:0005529
PhosphoSite+
KinaseNET
Biological Process:
GO:0016051
GO:0006112
GO:0006002
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y10
G
I
F
A
Y
M
N
Y
R
V
P
R
T
R
K
Site 2
T22
T
R
K
E
I
F
E
T
L
I
K
G
L
Q
R
Site 3
Y32
K
G
L
Q
R
L
E
Y
R
G
Y
D
S
A
G
Site 4
Y35
Q
R
L
E
Y
R
G
Y
D
S
A
G
V
A
I
Site 5
Y71
K
A
L
D
E
E
L
Y
K
Q
D
S
M
D
L
Site 6
S75
E
E
L
Y
K
Q
D
S
M
D
L
K
V
E
F
Site 7
S100
W
A
T
H
G
V
P
S
A
V
N
S
H
P
Q
Site 8
S104
G
V
P
S
A
V
N
S
H
P
Q
R
S
D
K
Site 9
S109
V
N
S
H
P
Q
R
S
D
K
G
N
E
F
V
Site 10
S135
D
L
R
K
F
L
E
S
K
G
Y
E
F
E
S
Site 11
Y138
K
F
L
E
S
K
G
Y
E
F
E
S
E
T
D
Site 12
T146
E
F
E
S
E
T
D
T
E
T
I
A
K
L
I
Site 13
T148
E
S
E
T
D
T
E
T
I
A
K
L
I
K
Y
Site 14
Y155
T
I
A
K
L
I
K
Y
V
F
D
N
R
E
T
Site 15
T162
Y
V
F
D
N
R
E
T
E
D
I
T
F
S
T
Site 16
T166
N
R
E
T
E
D
I
T
F
S
T
L
V
E
R
Site 17
T198
Y
P
G
E
A
V
A
T
R
R
G
S
P
L
L
Site 18
S202
A
V
A
T
R
R
G
S
P
L
L
I
G
V
R
Site 19
S210
P
L
L
I
G
V
R
S
K
Y
K
L
S
T
E
Site 20
Y212
L
I
G
V
R
S
K
Y
K
L
S
T
E
Q
I
Site 21
S215
V
R
S
K
Y
K
L
S
T
E
Q
I
P
I
L
Site 22
Y223
T
E
Q
I
P
I
L
Y
R
T
C
T
L
E
N
Site 23
T227
P
I
L
Y
R
T
C
T
L
E
N
V
K
N
I
Site 24
S244
T
R
M
K
R
L
D
S
S
A
C
L
H
A
V
Site 25
S245
R
M
K
R
L
D
S
S
A
C
L
H
A
V
G
Site 26
S291
A
V
A
D
G
K
L
S
I
H
R
V
K
R
S
Site 27
S298
S
I
H
R
V
K
R
S
A
S
D
D
P
S
R
Site 28
S300
H
R
V
K
R
S
A
S
D
D
P
S
R
A
I
Site 29
S304
R
S
A
S
D
D
P
S
R
A
I
Q
T
L
Q
Site 30
S336
E
I
F
E
Q
P
E
S
V
F
N
T
M
R
G
Site 31
T340
Q
P
E
S
V
F
N
T
M
R
G
R
V
N
F
Site 32
T349
R
G
R
V
N
F
E
T
N
T
V
L
L
G
G
Site 33
T410
S
D
F
L
D
R
N
T
P
V
F
R
D
D
V
Site 34
S422
D
D
V
C
F
F
I
S
Q
S
G
E
T
A
D
Site 35
T430
Q
S
G
E
T
A
D
T
L
L
A
L
R
Y
C
Site 36
Y436
D
T
L
L
A
L
R
Y
C
K
D
R
G
A
L
Site 37
S454
V
T
N
T
V
G
S
S
I
S
R
E
T
D
C
Site 38
T459
G
S
S
I
S
R
E
T
D
C
G
V
H
I
N
Site 39
S499
M
M
S
E
D
R
I
S
L
Q
N
R
R
Q
E
Site 40
S513
E
I
I
R
G
L
R
S
L
P
E
L
I
K
E
Site 41
S523
E
L
I
K
E
V
L
S
L
E
E
K
I
H
D
Site 42
Y550
V
M
G
R
G
Y
N
Y
A
T
C
L
E
G
A
Site 43
S622
G
R
P
I
I
L
C
S
K
D
D
T
E
S
S
Site 44
T626
I
L
C
S
K
D
D
T
E
S
S
K
F
A
Y
Site 45
Y633
T
E
S
S
K
F
A
Y
K
T
I
E
L
P
H
Site 46
T635
S
S
K
F
A
Y
K
T
I
E
L
P
H
T
V
Site 47
Y667
H
L
A
V
L
R
G
Y
D
V
D
F
P
R
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation