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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RGS11
Full Name:
Regulator of G-protein signaling 11
Alias:
RS11
Type:
Heterotrimeric G-protein complex protein
Mass (Da):
52946
Number AA:
467
UniProt ID:
O94810
International Prot ID:
IPI00015558
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005834
Uniprot
OncoNet
Molecular Function:
GO:0005096
GO:0004871
PhosphoSite+
KinaseNET
Biological Process:
GO:0007186
GO:0007242
GO:0009968
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S40
D
Q
G
V
K
M
R
S
Q
R
L
L
V
T
V
Site 2
Y86
L
V
Q
H
G
Y
I
Y
P
L
R
D
P
R
S
Site 3
S93
Y
P
L
R
D
P
R
S
L
M
L
R
P
D
E
Site 4
T101
L
M
L
R
P
D
E
T
P
Y
R
F
Q
T
P
Site 5
Y103
L
R
P
D
E
T
P
Y
R
F
Q
T
P
Y
F
Site 6
T107
E
T
P
Y
R
F
Q
T
P
Y
F
W
T
S
T
Site 7
Y109
P
Y
R
F
Q
T
P
Y
F
W
T
S
T
L
R
Site 8
T114
T
P
Y
F
W
T
S
T
L
R
P
A
A
E
L
Site 9
Y123
R
P
A
A
E
L
D
Y
A
I
Y
L
A
K
K
Site 10
Y126
A
E
L
D
Y
A
I
Y
L
A
K
K
N
I
R
Site 11
T137
K
N
I
R
K
R
G
T
L
V
D
Y
E
K
D
Site 12
Y141
K
R
G
T
L
V
D
Y
E
K
D
C
Y
D
R
Site 13
Y146
V
D
Y
E
K
D
C
Y
D
R
L
H
K
K
I
Site 14
S175
L
R
A
A
K
Q
R
S
K
G
D
R
L
V
I
Site 15
S211
E
Q
G
P
G
R
G
S
C
A
A
S
R
V
L
Site 16
S215
G
R
G
S
C
A
A
S
R
V
L
M
T
K
S
Site 17
S222
S
R
V
L
M
T
K
S
A
D
F
H
K
R
E
Site 18
Y232
F
H
K
R
E
I
E
Y
F
R
K
A
L
G
R
Site 19
T240
F
R
K
A
L
G
R
T
R
V
K
S
S
V
C
Site 20
S244
L
G
R
T
R
V
K
S
S
V
C
L
E
A
Y
Site 21
S245
G
R
T
R
V
K
S
S
V
C
L
E
A
Y
L
Site 22
S266
G
P
H
D
P
L
V
S
G
C
L
P
S
N
P
Site 23
S271
L
V
S
G
C
L
P
S
N
P
W
I
S
D
N
Site 24
S303
R
V
E
R
W
G
F
S
F
R
E
L
L
E
D
Site 25
S326
D
F
L
G
K
E
F
S
G
E
N
L
S
F
W
Site 26
S331
E
F
S
G
E
N
L
S
F
W
E
A
C
E
E
Site 27
Y341
E
A
C
E
E
L
R
Y
G
A
Q
A
Q
V
P
Site 28
T373
W
V
N
I
D
S
R
T
M
E
Q
T
L
E
G
Site 29
T377
D
S
R
T
M
E
Q
T
L
E
G
L
R
Q
P
Site 30
Y387
G
L
R
Q
P
H
R
Y
V
L
D
D
A
Q
L
Site 31
S404
Y
M
L
M
K
K
D
S
Y
P
R
F
L
K
S
Site 32
Y405
M
L
M
K
K
D
S
Y
P
R
F
L
K
S
D
Site 33
S411
S
Y
P
R
F
L
K
S
D
M
Y
K
A
L
L
Site 34
Y414
R
F
L
K
S
D
M
Y
K
A
L
L
A
E
A
Site 35
T435
K
R
R
V
F
P
F
T
W
R
P
R
H
S
S
Site 36
S441
F
T
W
R
P
R
H
S
S
P
S
P
A
L
L
Site 37
S442
T
W
R
P
R
H
S
S
P
S
P
A
L
L
P
Site 38
S444
R
P
R
H
S
S
P
S
P
A
L
L
P
T
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation