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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NOL4
Full Name:
Nucleolar protein 4
Alias:
Nucleolar-localized protein
Type:
Mass (Da):
58419
Number AA:
524
UniProt ID:
O94818
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y22
H
A
G
Q
K
R
T
Y
K
A
I
S
E
S
Y
Site 2
T58
M
H
L
N
P
D
G
T
D
H
K
D
N
G
K
Site 3
T68
K
D
N
G
K
P
P
T
L
V
T
S
M
I
D
Site 4
S95
M
K
L
Q
L
L
N
S
Q
Q
D
E
D
E
S
Site 5
S102
S
Q
Q
D
E
D
E
S
S
I
E
S
D
E
F
Site 6
S103
Q
Q
D
E
D
E
S
S
I
E
S
D
E
F
D
Site 7
S106
E
D
E
S
S
I
E
S
D
E
F
D
M
S
D
Site 8
S112
E
S
D
E
F
D
M
S
D
S
T
R
M
S
A
Site 9
S114
D
E
F
D
M
S
D
S
T
R
M
S
A
V
N
Site 10
T115
E
F
D
M
S
D
S
T
R
M
S
A
V
N
S
Site 11
S118
M
S
D
S
T
R
M
S
A
V
N
S
D
L
S
Site 12
S122
T
R
M
S
A
V
N
S
D
L
S
S
N
L
E
Site 13
S125
S
A
V
N
S
D
L
S
S
N
L
E
E
R
M
Site 14
S126
A
V
N
S
D
L
S
S
N
L
E
E
R
M
Q
Site 15
S134
N
L
E
E
R
M
Q
S
P
Q
N
L
H
G
Q
Site 16
S146
H
G
Q
Q
D
D
D
S
A
A
E
S
F
N
G
Site 17
S150
D
D
D
S
A
A
E
S
F
N
G
N
E
T
L
Site 18
T156
E
S
F
N
G
N
E
T
L
G
H
S
S
I
A
Site 19
S160
G
N
E
T
L
G
H
S
S
I
A
S
G
G
T
Site 20
S161
N
E
T
L
G
H
S
S
I
A
S
G
G
T
H
Site 21
S164
L
G
H
S
S
I
A
S
G
G
T
H
S
R
E
Site 22
S169
I
A
S
G
G
T
H
S
R
E
M
G
D
S
N
Site 23
S175
H
S
R
E
M
G
D
S
N
S
D
G
K
T
G
Site 24
S177
R
E
M
G
D
S
N
S
D
G
K
T
G
L
E
Site 25
T181
D
S
N
S
D
G
K
T
G
L
E
Q
D
E
Q
Site 26
S193
D
E
Q
P
L
N
L
S
D
S
P
L
S
A
Q
Site 27
S195
Q
P
L
N
L
S
D
S
P
L
S
A
Q
L
T
Site 28
S198
N
L
S
D
S
P
L
S
A
Q
L
T
S
E
Y
Site 29
T202
S
P
L
S
A
Q
L
T
S
E
Y
R
I
D
D
Site 30
Y218
N
S
N
G
K
N
K
Y
K
N
L
L
I
S
D
Site 31
S224
K
Y
K
N
L
L
I
S
D
L
K
M
E
R
E
Site 32
S237
R
E
A
R
E
N
G
S
K
S
P
A
H
S
Y
Site 33
S239
A
R
E
N
G
S
K
S
P
A
H
S
Y
S
S
Site 34
S243
G
S
K
S
P
A
H
S
Y
S
S
Y
D
S
G
Site 35
Y244
S
K
S
P
A
H
S
Y
S
S
Y
D
S
G
K
Site 36
S245
K
S
P
A
H
S
Y
S
S
Y
D
S
G
K
N
Site 37
S246
S
P
A
H
S
Y
S
S
Y
D
S
G
K
N
E
Site 38
Y247
P
A
H
S
Y
S
S
Y
D
S
G
K
N
E
S
Site 39
S249
H
S
Y
S
S
Y
D
S
G
K
N
E
S
V
D
Site 40
S254
Y
D
S
G
K
N
E
S
V
D
R
G
A
E
D
Site 41
S263
D
R
G
A
E
D
L
S
L
N
R
G
D
E
D
Site 42
S280
D
H
E
D
H
D
D
S
E
K
V
N
E
T
D
Site 43
S316
L
D
R
M
V
P
I
S
K
Q
P
K
E
K
I
Site 44
S329
K
I
Q
A
I
I
D
S
C
R
R
Q
F
P
E
Site 45
Y337
C
R
R
Q
F
P
E
Y
Q
E
R
A
R
K
R
Site 46
T347
R
A
R
K
R
I
R
T
Y
L
K
S
C
R
R
Site 47
Y348
A
R
K
R
I
R
T
Y
L
K
S
C
R
R
M
Site 48
S351
R
I
R
T
Y
L
K
S
C
R
R
M
K
R
S
Site 49
S358
S
C
R
R
M
K
R
S
G
F
E
M
S
R
P
Site 50
S363
K
R
S
G
F
E
M
S
R
P
I
P
S
H
L
Site 51
S368
E
M
S
R
P
I
P
S
H
L
T
S
A
V
A
Site 52
S381
V
A
E
S
I
L
A
S
A
C
E
S
E
S
R
Site 53
S385
I
L
A
S
A
C
E
S
E
S
R
N
A
A
K
Site 54
S403
L
E
R
Q
Q
D
E
S
A
P
A
D
K
Q
C
Site 55
S420
E
A
T
Q
A
T
Y
S
T
S
A
V
P
G
S
Site 56
S422
T
Q
A
T
Y
S
T
S
A
V
P
G
S
Q
D
Site 57
S427
S
T
S
A
V
P
G
S
Q
D
V
L
Y
I
N
Site 58
Y432
P
G
S
Q
D
V
L
Y
I
N
G
N
G
T
Y
Site 59
Y441
N
G
N
G
T
Y
S
Y
H
S
Y
R
G
L
G
Site 60
S443
N
G
T
Y
S
Y
H
S
Y
R
G
L
G
G
G
Site 61
Y444
G
T
Y
S
Y
H
S
Y
R
G
L
G
G
G
L
Site 62
S458
L
L
N
L
N
D
A
S
S
S
G
P
T
D
L
Site 63
S459
L
N
L
N
D
A
S
S
S
G
P
T
D
L
S
Site 64
S460
N
L
N
D
A
S
S
S
G
P
T
D
L
S
M
Site 65
S466
S
S
G
P
T
D
L
S
M
K
R
Q
L
A
T
Site 66
T473
S
M
K
R
Q
L
A
T
S
S
G
S
S
S
S
Site 67
S474
M
K
R
Q
L
A
T
S
S
G
S
S
S
S
S
Site 68
S475
K
R
Q
L
A
T
S
S
G
S
S
S
S
S
N
Site 69
S477
Q
L
A
T
S
S
G
S
S
S
S
S
N
S
R
Site 70
S478
L
A
T
S
S
G
S
S
S
S
S
N
S
R
P
Site 71
S479
A
T
S
S
G
S
S
S
S
S
N
S
R
P
Q
Site 72
S480
T
S
S
G
S
S
S
S
S
N
S
R
P
Q
L
Site 73
S481
S
S
G
S
S
S
S
S
N
S
R
P
Q
L
S
Site 74
S483
G
S
S
S
S
S
N
S
R
P
Q
L
S
P
T
Site 75
S488
S
N
S
R
P
Q
L
S
P
T
E
I
N
A
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation