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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ATP10B
Full Name:
Probable phospholipid-transporting ATPase VB
Alias:
ATPase class V type 10B
Type:
Mass (Da):
165391
Number AA:
1461
UniProt ID:
O94823
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S25
D
G
F
P
H
C
P
S
E
T
T
P
L
L
S
Site 2
T28
P
H
C
P
S
E
T
T
P
L
L
S
P
E
K
Site 3
S32
S
E
T
T
P
L
L
S
P
E
K
G
R
Q
S
Site 4
S39
S
P
E
K
G
R
Q
S
Y
N
L
T
Q
Q
R
Site 5
Y40
P
E
K
G
R
Q
S
Y
N
L
T
Q
Q
R
V
Site 6
T43
G
R
Q
S
Y
N
L
T
Q
Q
R
V
V
F
P
Site 7
Y66
W
E
E
V
S
R
R
Y
P
G
N
R
T
C
T
Site 8
T73
Y
P
G
N
R
T
C
T
T
K
Y
T
L
F
T
Site 9
Y76
N
R
T
C
T
T
K
Y
T
L
F
T
F
L
P
Site 10
T77
R
T
C
T
T
K
Y
T
L
F
T
F
L
P
R
Site 11
S150
F
D
K
A
I
N
C
S
N
I
R
I
Y
E
R
Site 12
Y155
N
C
S
N
I
R
I
Y
E
R
K
E
Q
T
Y
Site 13
Y162
Y
E
R
K
E
Q
T
Y
V
Q
K
C
W
K
D
Site 14
S223
R
C
V
V
K
G
F
S
Q
Q
E
V
Q
F
E
Site 15
S300
T
K
A
M
L
N
N
S
G
P
R
Y
K
R
S
Site 16
Y304
L
N
N
S
G
P
R
Y
K
R
S
K
I
E
R
Site 17
S307
S
G
P
R
Y
K
R
S
K
I
E
R
R
M
N
Site 18
S356
D
V
P
D
A
N
G
S
F
L
P
S
A
L
G
Site 19
Y405
L
S
N
D
L
D
L
Y
D
E
E
T
D
L
S
Site 20
T409
L
D
L
Y
D
E
E
T
D
L
S
I
Q
C
R
Site 21
S412
Y
D
E
E
T
D
L
S
I
Q
C
R
A
L
N
Site 22
Y429
E
D
L
G
Q
I
Q
Y
I
F
S
D
K
T
G
Site 23
T435
Q
Y
I
F
S
D
K
T
G
T
L
T
E
N
K
Site 24
T439
S
D
K
T
G
T
L
T
E
N
K
M
V
F
R
Site 25
T449
K
M
V
F
R
R
C
T
I
M
G
S
E
Y
S
Site 26
T466
E
N
A
K
R
L
E
T
P
K
E
L
D
S
D
Site 27
S472
E
T
P
K
E
L
D
S
D
G
E
E
W
T
Q
Site 28
Y480
D
G
E
E
W
T
Q
Y
Q
C
L
S
F
S
A
Site 29
T495
R
W
A
Q
D
P
A
T
M
R
S
Q
K
G
A
Site 30
S498
Q
D
P
A
T
M
R
S
Q
K
G
A
Q
P
L
Site 31
S508
G
A
Q
P
L
R
R
S
Q
S
A
R
V
P
I
Site 32
S510
Q
P
L
R
R
S
Q
S
A
R
V
P
I
Q
G
Site 33
Y519
R
V
P
I
Q
G
H
Y
R
Q
R
S
M
G
H
Site 34
S523
Q
G
H
Y
R
Q
R
S
M
G
H
R
E
S
S
Site 35
S529
R
S
M
G
H
R
E
S
S
Q
P
P
V
A
F
Site 36
S530
S
M
G
H
R
E
S
S
Q
P
P
V
A
F
S
Site 37
S537
S
Q
P
P
V
A
F
S
S
S
I
E
K
D
V
Site 38
S539
P
P
V
A
F
S
S
S
I
E
K
D
V
T
P
Site 39
T545
S
S
I
E
K
D
V
T
P
D
K
N
L
L
T
Site 40
T552
T
P
D
K
N
L
L
T
K
V
R
D
A
A
L
Site 41
T563
D
A
A
L
W
L
E
T
L
S
D
S
R
P
A
Site 42
S565
A
L
W
L
E
T
L
S
D
S
R
P
A
K
A
Site 43
S567
W
L
E
T
L
S
D
S
R
P
A
K
A
S
L
Site 44
S573
D
S
R
P
A
K
A
S
L
S
T
T
S
S
I
Site 45
S575
R
P
A
K
A
S
L
S
T
T
S
S
I
A
D
Site 46
S596
I
C
N
S
V
M
V
S
T
T
T
E
P
R
Q
Site 47
T606
T
E
P
R
Q
R
V
T
I
K
P
S
S
K
A
Site 48
S611
R
V
T
I
K
P
S
S
K
A
L
G
T
S
L
Site 49
S617
S
S
K
A
L
G
T
S
L
E
K
I
Q
Q
L
Site 50
S632
F
Q
K
L
K
L
L
S
L
S
Q
S
F
S
S
Site 51
S634
K
L
K
L
L
S
L
S
Q
S
F
S
S
T
A
Site 52
S636
K
L
L
S
L
S
Q
S
F
S
S
T
A
P
S
Site 53
S638
L
S
L
S
Q
S
F
S
S
T
A
P
S
D
T
Site 54
S639
S
L
S
Q
S
F
S
S
T
A
P
S
D
T
D
Site 55
T640
L
S
Q
S
F
S
S
T
A
P
S
D
T
D
L
Site 56
S643
S
F
S
S
T
A
P
S
D
T
D
L
G
E
S
Site 57
T645
S
S
T
A
P
S
D
T
D
L
G
E
S
L
G
Site 58
S650
S
D
T
D
L
G
E
S
L
G
A
N
V
A
T
Site 59
S660
A
N
V
A
T
T
D
S
D
E
R
D
D
A
S
Site 60
S667
S
D
E
R
D
D
A
S
V
C
S
G
G
D
S
Site 61
S670
R
D
D
A
S
V
C
S
G
G
D
S
T
D
D
Site 62
S674
S
V
C
S
G
G
D
S
T
D
D
G
G
Y
R
Site 63
T675
V
C
S
G
G
D
S
T
D
D
G
G
Y
R
S
Site 64
Y680
D
S
T
D
D
G
G
Y
R
S
S
M
W
D
Q
Site 65
S682
T
D
D
G
G
Y
R
S
S
M
W
D
Q
G
D
Site 66
S693
D
Q
G
D
I
L
E
S
G
S
G
T
S
L
E
Site 67
S695
G
D
I
L
E
S
G
S
G
T
S
L
E
E
A
Site 68
T708
E
A
L
E
A
P
A
T
D
L
A
R
P
E
F
Site 69
Y717
L
A
R
P
E
F
C
Y
E
A
E
S
P
D
E
Site 70
S721
E
F
C
Y
E
A
E
S
P
D
E
A
A
L
V
Site 71
T737
A
A
H
A
Y
S
F
T
L
V
S
R
T
P
E
Site 72
T742
S
F
T
L
V
S
R
T
P
E
Q
V
T
V
R
Site 73
S774
D
S
V
R
K
R
M
S
V
V
V
R
H
P
L
Site 74
T822
L
R
K
I
R
A
R
T
Q
K
H
L
D
L
Y
Site 75
Y829
T
Q
K
H
L
D
L
Y
A
R
D
G
L
R
T
Site 76
T836
Y
A
R
D
G
L
R
T
L
C
I
A
K
K
V
Site 77
S845
C
I
A
K
K
V
V
S
E
E
D
F
R
R
W
Site 78
S854
E
D
F
R
R
W
A
S
F
R
R
E
A
E
A
Site 79
S862
F
R
R
E
A
E
A
S
L
D
N
R
D
E
L
Site 80
T900
L
Q
E
G
V
P
D
T
I
A
T
L
R
E
A
Site 81
T935
S
C
R
L
L
N
Q
T
D
T
V
Y
T
I
N
Site 82
T937
R
L
L
N
Q
T
D
T
V
Y
T
I
N
T
E
Site 83
Y939
L
N
Q
T
D
T
V
Y
T
I
N
T
E
N
Q
Site 84
T948
I
N
T
E
N
Q
E
T
C
E
S
I
L
N
C
Site 85
S980
L
F
G
F
R
L
P
S
K
T
P
S
I
T
S
Site 86
T982
G
F
R
L
P
S
K
T
P
S
I
T
S
E
A
Site 87
S984
R
L
P
S
K
T
P
S
I
T
S
E
A
V
V
Site 88
T1019
E
K
K
F
L
E
L
T
Q
Y
C
R
S
V
L
Site 89
S1030
R
S
V
L
C
C
R
S
T
P
L
Q
K
S
M
Site 90
S1036
R
S
T
P
L
Q
K
S
M
I
V
K
L
V
R
Site 91
T1050
R
D
K
L
R
V
M
T
L
S
I
G
D
G
A
Site 92
S1052
K
L
R
V
M
T
L
S
I
G
D
G
A
N
D
Site 93
Y1181
L
L
A
L
P
E
L
Y
K
S
G
Q
N
S
E
Site 94
S1183
A
L
P
E
L
Y
K
S
G
Q
N
S
E
C
Y
Site 95
S1187
L
Y
K
S
G
Q
N
S
E
C
Y
N
L
S
T
Site 96
Y1190
S
G
Q
N
S
E
C
Y
N
L
S
T
F
W
I
Site 97
Y1286
C
N
S
P
T
N
P
Y
W
V
M
E
G
Q
L
Site 98
S1326
L
Q
G
T
C
G
K
S
L
I
S
K
A
Q
K
Site 99
S1348
K
R
N
L
E
I
Q
S
W
R
S
R
Q
R
P
Site 100
T1365
V
P
E
V
A
R
P
T
H
H
P
V
S
S
I
Site 101
S1370
R
P
T
H
H
P
V
S
S
I
T
G
Q
D
F
Site 102
S1378
S
I
T
G
Q
D
F
S
A
S
T
P
K
S
S
Site 103
S1380
T
G
Q
D
F
S
A
S
T
P
K
S
S
N
P
Site 104
T1381
G
Q
D
F
S
A
S
T
P
K
S
S
N
P
P
Site 105
S1384
F
S
A
S
T
P
K
S
S
N
P
P
K
R
K
Site 106
S1385
S
A
S
T
P
K
S
S
N
P
P
K
R
K
H
Site 107
T1405
L
H
E
Q
R
C
G
T
E
C
M
R
D
D
S
Site 108
S1412
T
E
C
M
R
D
D
S
C
S
G
D
S
S
A
Site 109
S1414
C
M
R
D
D
S
C
S
G
D
S
S
A
Q
L
Site 110
S1417
D
D
S
C
S
G
D
S
S
A
Q
L
S
S
G
Site 111
S1418
D
S
C
S
G
D
S
S
A
Q
L
S
S
G
E
Site 112
S1422
G
D
S
S
A
Q
L
S
S
G
E
H
L
L
G
Site 113
S1423
D
S
S
A
Q
L
S
S
G
E
H
L
L
G
P
Site 114
Y1436
G
P
N
R
I
M
A
Y
S
R
G
Q
T
D
M
Site 115
S1447
Q
T
D
M
C
R
C
S
K
R
S
S
H
R
R
Site 116
S1450
M
C
R
C
S
K
R
S
S
H
R
R
S
Q
S
Site 117
S1451
C
R
C
S
K
R
S
S
H
R
R
S
Q
S
S
Site 118
S1455
K
R
S
S
H
R
R
S
Q
S
S
L
T
I
_
Site 119
S1457
S
S
H
R
R
S
Q
S
S
L
T
I
_
_
_
Site 120
S1458
S
H
R
R
S
Q
S
S
L
T
I
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation