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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
IPO13
Full Name:
Importin-13
Alias:
Karyopherin-13;Ran-binding protein 13
Type:
Mass (Da):
108195
Number AA:
963
UniProt ID:
O94829
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y34
E
K
A
L
H
Q
L
Y
Y
D
P
N
I
E
N
Site 2
Y35
K
A
L
H
Q
L
Y
Y
D
P
N
I
E
N
K
Site 3
Y76
D
K
V
P
E
I
Q
Y
F
G
A
S
A
L
H
Site 4
S87
S
A
L
H
I
K
I
S
R
Y
W
S
D
I
P
Site 5
Y89
L
H
I
K
I
S
R
Y
W
S
D
I
P
T
D
Site 6
T95
R
Y
W
S
D
I
P
T
D
Q
Y
E
S
L
K
Site 7
Y98
S
D
I
P
T
D
Q
Y
E
S
L
K
A
Q
L
Site 8
T110
A
Q
L
F
T
Q
I
T
R
F
A
S
G
S
K
Site 9
S155
R
L
F
Q
A
E
D
S
P
V
D
G
Q
G
R
Site 10
T179
V
L
P
E
E
F
Q
T
S
R
L
P
Q
Y
R
Site 11
S180
L
P
E
E
F
Q
T
S
R
L
P
Q
Y
R
K
Site 12
T192
Y
R
K
G
L
V
R
T
S
L
A
V
E
C
G
Site 13
S193
R
K
G
L
V
R
T
S
L
A
V
E
C
G
A
Site 14
S213
E
Q
L
L
Q
Q
P
S
S
P
S
C
V
R
Q
Site 15
S214
Q
L
L
Q
Q
P
S
S
P
S
C
V
R
Q
K
Site 16
S258
Q
D
S
E
L
F
D
S
S
V
E
A
I
V
N
Site 17
S268
E
A
I
V
N
A
I
S
Q
P
D
A
Q
R
Y
Site 18
Y275
S
Q
P
D
A
Q
R
Y
V
N
T
L
L
K
L
Site 19
Y350
C
T
G
I
P
G
H
Y
P
V
N
E
T
T
S
Site 20
S358
P
V
N
E
T
T
S
S
L
T
L
T
F
W
Y
Site 21
T362
T
T
S
S
L
T
L
T
F
W
Y
T
L
Q
D
Site 22
S373
T
L
Q
D
D
I
L
S
F
E
A
E
K
Q
A
Site 23
Y382
E
A
E
K
Q
A
V
Y
Q
Q
V
Y
R
P
V
Site 24
Y409
Q
F
P
S
D
E
E
Y
G
F
W
S
S
D
E
Site 25
S414
E
E
Y
G
F
W
S
S
D
E
K
E
Q
F
R
Site 26
Y423
E
K
E
Q
F
R
I
Y
R
V
D
I
S
D
T
Site 27
T430
Y
R
V
D
I
S
D
T
L
M
Y
V
Y
E
M
Site 28
Y433
D
I
S
D
T
L
M
Y
V
Y
E
M
L
G
A
Site 29
T455
D
K
L
G
R
L
L
T
S
S
E
E
P
Y
S
Site 30
S457
L
G
R
L
L
T
S
S
E
E
P
Y
S
W
Q
Site 31
S462
T
S
S
E
E
P
Y
S
W
Q
H
T
E
A
L
Site 32
T466
E
P
Y
S
W
Q
H
T
E
A
L
L
Y
G
F
Site 33
Y471
Q
H
T
E
A
L
L
Y
G
F
Q
S
I
A
E
Site 34
T479
G
F
Q
S
I
A
E
T
I
D
V
N
Y
S
D
Site 35
S546
G
N
P
E
L
S
V
S
S
V
S
T
L
K
K
Site 36
S549
E
L
S
V
S
S
V
S
T
L
K
K
I
C
R
Site 37
T550
L
S
V
S
S
V
S
T
L
K
K
I
C
R
E
Site 38
Y560
K
I
C
R
E
C
K
Y
D
L
P
P
Y
A
A
Site 39
S615
K
N
L
H
S
L
I
S
P
Y
I
Q
Q
L
E
Site 40
S654
L
F
T
T
L
D
I
S
H
H
E
D
D
H
E
Site 41
Y735
C
E
M
L
G
R
M
Y
S
T
I
P
Q
A
S
Site 42
S736
E
M
L
G
R
M
Y
S
T
I
P
Q
A
S
A
Site 43
S792
D
H
P
D
I
V
D
S
F
M
Q
L
L
A
Q
Site 44
S853
P
R
C
G
E
V
E
S
V
G
K
V
V
Q
E
Site 45
S878
E
A
I
G
G
Q
A
S
R
S
L
M
D
C
F
Site 46
S880
I
G
G
Q
A
S
R
S
L
M
D
C
F
A
D
Site 47
S915
L
Q
P
P
G
F
P
S
A
R
L
S
P
E
Q
Site 48
S919
G
F
P
S
A
R
L
S
P
E
Q
K
D
T
F
Site 49
T925
L
S
P
E
Q
K
D
T
F
S
Q
Q
I
L
R
Site 50
S927
P
E
Q
K
D
T
F
S
Q
Q
I
L
R
E
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation