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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RHOBTB1
Full Name:
Rho-related BTB domain-containing protein 1
Alias:
KIAA0740; RHBT1
Type:
GTPase, monomeric, Rho family
Mass (Da):
79417
Number AA:
696
UniProt ID:
O94844
International Prot ID:
IPI00001317
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0005525
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007264
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y7
_
M
D
A
D
M
D
Y
E
R
P
N
V
E
T
Site 2
T41
R
A
C
N
T
T
L
T
Q
Y
Q
L
L
A
T
Site 3
S69
C
Q
E
V
L
E
R
S
R
D
V
V
D
E
V
Site 4
S77
R
D
V
V
D
E
V
S
V
S
L
R
L
W
D
Site 5
T85
V
S
L
R
L
W
D
T
F
G
D
H
H
K
D
Site 6
Y97
H
K
D
R
R
F
A
Y
G
R
S
D
V
V
V
Site 7
S114
F
S
I
A
N
P
N
S
L
N
H
V
K
S
M
Site 8
Y146
G
C
Q
L
D
L
R
Y
A
D
L
E
A
V
N
Site 9
Y185
A
K
E
L
G
L
P
Y
Y
E
T
S
V
F
D
Site 10
Y186
K
E
L
G
L
P
Y
Y
E
T
S
V
F
D
Q
Site 11
T188
L
G
L
P
Y
Y
E
T
S
V
F
D
Q
F
G
Site 12
Y284
H
I
F
A
H
R
I
Y
L
A
T
S
S
S
K
Site 13
T287
A
H
R
I
Y
L
A
T
S
S
S
K
F
Y
D
Site 14
S303
F
L
M
E
C
E
E
S
P
N
G
S
E
G
A
Site 15
S307
C
E
E
S
P
N
G
S
E
G
A
C
E
K
E
Site 16
S326
D
F
Q
G
R
I
L
S
V
D
P
E
E
E
R
Site 17
S348
P
Q
A
D
Q
W
K
S
S
N
K
S
L
V
E
Site 18
S352
Q
W
K
S
S
N
K
S
L
V
E
A
L
G
L
Site 19
T370
G
A
V
P
E
T
Q
T
L
T
G
W
S
K
G
Site 20
T372
V
P
E
T
Q
T
L
T
G
W
S
K
G
F
I
Site 21
T398
S
K
R
M
G
P
M
T
V
V
R
M
D
A
S
Site 22
S405
T
V
V
R
M
D
A
S
V
Q
P
G
P
F
R
Site 23
Y419
R
T
L
L
Q
F
L
Y
T
G
Q
L
D
E
K
Site 24
S480
N
R
I
K
E
C
L
S
K
G
T
F
S
D
V
Site 25
T483
K
E
C
L
S
K
G
T
F
S
D
V
T
F
K
Site 26
S485
C
L
S
K
G
T
F
S
D
V
T
F
K
L
D
Site 27
T488
K
G
T
F
S
D
V
T
F
K
L
D
D
G
A
Site 28
S524
S
F
V
E
S
A
N
S
E
V
Y
L
P
N
I
Site 29
Y542
S
M
Q
A
V
L
D
Y
L
Y
T
K
Q
L
S
Site 30
Y544
Q
A
V
L
D
Y
L
Y
T
K
Q
L
S
P
N
Site 31
T545
A
V
L
D
Y
L
Y
T
K
Q
L
S
P
N
L
Site 32
S549
Y
L
Y
T
K
Q
L
S
P
N
L
D
L
D
P
Site 33
S637
K
F
R
K
E
I
K
S
K
S
A
D
N
Q
E
Site 34
S639
R
K
E
I
K
S
K
S
A
D
N
Q
E
Y
F
Site 35
Y645
K
S
A
D
N
Q
E
Y
F
E
R
H
R
W
P
Site 36
Y656
H
R
W
P
P
V
W
Y
L
K
E
E
D
H
Y
Site 37
Y663
Y
L
K
E
E
D
H
Y
Q
R
V
K
R
E
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation