KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
DDN
Full Name:
Dendrin
Alias:
DEND; KIAA0749
Type:
Mass (Da):
75996
Number AA:
711
UniProt ID:
O94850
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0042995
GO:0005783
GO:0019898
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
L
D
G
P
L
F
S
E
G
P
D
S
P
R
Site 2
S13
L
F
S
E
G
P
D
S
P
R
E
L
Q
D
E
Site 3
S22
R
E
L
Q
D
E
E
S
G
S
C
L
W
V
Q
Site 4
S24
L
Q
D
E
E
S
G
S
C
L
W
V
Q
K
S
Site 5
S42
V
I
E
V
K
T
I
S
C
H
Y
S
R
R
A
Site 6
Y45
V
K
T
I
S
C
H
Y
S
R
R
A
P
S
R
Site 7
S46
K
T
I
S
C
H
Y
S
R
R
A
P
S
R
Q
Site 8
S51
H
Y
S
R
R
A
P
S
R
Q
P
M
D
F
Q
Site 9
T70
A
R
G
F
Q
N
R
T
C
G
P
R
P
G
S
Site 10
S77
T
C
G
P
R
P
G
S
P
Q
P
P
P
R
R
Site 11
S88
P
P
R
R
P
W
A
S
R
V
L
Q
E
A
T
Site 12
T125
Q
E
R
E
A
K
E
T
E
R
K
R
R
K
A
Site 13
S138
K
A
G
G
A
R
R
S
P
P
G
R
P
R
P
Site 14
S178
V
G
R
A
P
R
P
S
A
Q
P
Q
S
D
P
Site 15
S183
R
P
S
A
Q
P
Q
S
D
P
G
S
A
W
A
Site 16
S187
Q
P
Q
S
D
P
G
S
A
W
A
G
P
W
G
Site 17
S202
G
R
R
P
G
P
P
S
Y
E
A
H
L
L
L
Site 18
Y203
R
R
P
G
P
P
S
Y
E
A
H
L
L
L
R
Site 19
S212
A
H
L
L
L
R
G
S
A
G
T
A
P
R
R
Site 20
T215
L
L
R
G
S
A
G
T
A
P
R
R
R
W
D
Site 21
Y227
R
W
D
R
P
P
P
Y
V
A
P
P
S
Y
E
Site 22
S232
P
P
Y
V
A
P
P
S
Y
E
G
P
H
R
T
Site 23
Y233
P
Y
V
A
P
P
S
Y
E
G
P
H
R
T
L
Site 24
T242
G
P
H
R
T
L
G
T
K
R
G
P
G
N
S
Site 25
S249
T
K
R
G
P
G
N
S
Q
V
P
T
S
S
A
Site 26
T253
P
G
N
S
Q
V
P
T
S
S
A
P
A
A
T
Site 27
S254
G
N
S
Q
V
P
T
S
S
A
P
A
A
T
P
Site 28
S255
N
S
Q
V
P
T
S
S
A
P
A
A
T
P
A
Site 29
T260
T
S
S
A
P
A
A
T
P
A
R
T
D
G
G
Site 30
Y278
K
R
L
D
P
R
I
Y
R
D
V
L
G
A
W
Site 31
S297
G
Q
G
L
L
G
G
S
P
G
C
G
A
A
R
Site 32
S327
L
A
A
A
D
L
N
S
G
S
D
S
H
P
Q
Site 33
S329
A
A
D
L
N
S
G
S
D
S
H
P
Q
A
K
Site 34
S331
D
L
N
S
G
S
D
S
H
P
Q
A
K
A
T
Site 35
S364
A
P
H
P
A
P
R
S
R
H
H
L
K
G
S
Site 36
S371
S
R
H
H
L
K
G
S
R
E
G
K
E
G
E
Site 37
S389
F
P
K
C
W
I
P
S
P
K
K
Q
P
P
R
Site 38
S398
K
K
Q
P
P
R
H
S
Q
T
L
P
R
P
W
Site 39
T400
Q
P
P
R
H
S
Q
T
L
P
R
P
W
A
P
Site 40
S415
G
G
T
G
W
R
E
S
L
G
L
G
E
G
A
Site 41
T426
G
E
G
A
G
P
E
T
L
E
G
W
K
A
T
Site 42
T438
K
A
T
R
R
A
H
T
L
P
R
S
S
Q
G
Site 43
S442
R
A
H
T
L
P
R
S
S
Q
G
L
S
R
G
Site 44
S443
A
H
T
L
P
R
S
S
Q
G
L
S
R
G
E
Site 45
S447
P
R
S
S
Q
G
L
S
R
G
E
G
V
F
V
Site 46
Y466
C
V
V
I
R
S
Q
Y
V
P
T
P
R
T
Q
Site 47
T469
I
R
S
Q
Y
V
P
T
P
R
T
Q
Q
V
Q
Site 48
T472
Q
Y
V
P
T
P
R
T
Q
Q
V
Q
L
L
P
Site 49
S489
V
T
R
V
V
G
D
S
P
S
Q
S
K
P
G
Site 50
S491
R
V
V
G
D
S
P
S
Q
S
K
P
G
K
E
Site 51
S493
V
G
D
S
P
S
Q
S
K
P
G
K
E
E
G
Site 52
T504
K
E
E
G
E
G
A
T
V
F
P
S
P
C
Q
Site 53
S508
E
G
A
T
V
F
P
S
P
C
Q
K
R
L
S
Site 54
S515
S
P
C
Q
K
R
L
S
S
S
R
L
L
H
Q
Site 55
S516
P
C
Q
K
R
L
S
S
S
R
L
L
H
Q
P
Site 56
S539
E
G
G
R
P
G
D
S
T
L
E
E
R
T
F
Site 57
T540
G
G
R
P
G
D
S
T
L
E
E
R
T
F
R
Site 58
T545
D
S
T
L
E
E
R
T
F
R
I
L
G
L
P
Site 59
T563
V
N
L
R
D
A
P
T
Q
P
G
S
P
E
H
Site 60
S567
D
A
P
T
Q
P
G
S
P
E
H
Q
A
L
G
Site 61
S587
A
Q
G
R
A
E
G
S
E
V
A
V
V
Q
R
Site 62
T603
A
G
R
G
W
A
R
T
P
G
P
Y
A
G
A
Site 63
S616
G
A
L
R
E
A
V
S
R
I
R
R
H
T
A
Site 64
T622
V
S
R
I
R
R
H
T
A
P
D
S
D
T
D
Site 65
S626
R
R
H
T
A
P
D
S
D
T
D
E
A
E
E
Site 66
T628
H
T
A
P
D
S
D
T
D
E
A
E
E
L
S
Site 67
S635
T
D
E
A
E
E
L
S
V
H
S
G
S
S
D
Site 68
S638
A
E
E
L
S
V
H
S
G
S
S
D
G
S
D
Site 69
S644
H
S
G
S
S
D
G
S
D
T
E
A
P
G
A
Site 70
T646
G
S
S
D
G
S
D
T
E
A
P
G
A
S
W
Site 71
S652
D
T
E
A
P
G
A
S
W
R
N
E
R
T
L
Site 72
S665
T
L
P
E
V
G
N
S
S
P
E
E
D
G
K
Site 73
S666
L
P
E
V
G
N
S
S
P
E
E
D
G
K
T
Site 74
T673
S
P
E
E
D
G
K
T
A
E
L
S
D
S
V
Site 75
S677
D
G
K
T
A
E
L
S
D
S
V
G
E
I
L
Site 76
S679
K
T
A
E
L
S
D
S
V
G
E
I
L
D
V
Site 77
T703
G
V
R
D
I
R
G
T
Q
Q
G
N
R
K
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation