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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TMEM63A
Full Name:
Transmembrane protein 63A
Alias:
TM63A
Type:
Uncharacterized protein
Mass (Da):
92126
Number AA:
807
UniProt ID:
O94886
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
P
F
L
E
L
W
Q
S
K
A
V
S
I
R
E
Site 2
S16
L
W
Q
S
K
A
V
S
I
R
E
Q
L
G
L
Site 3
S30
L
G
D
R
P
N
D
S
Y
C
Y
N
S
A
K
Site 4
Y31
G
D
R
P
N
D
S
Y
C
Y
N
S
A
K
N
Site 5
Y33
R
P
N
D
S
Y
C
Y
N
S
A
K
N
S
T
Site 6
S35
N
D
S
Y
C
Y
N
S
A
K
N
S
T
V
L
Site 7
S39
C
Y
N
S
A
K
N
S
T
V
L
Q
G
V
T
Site 8
Y78
I
R
R
R
F
W
D
Y
G
R
I
A
L
V
S
Site 9
S85
Y
G
R
I
A
L
V
S
E
A
D
S
E
S
R
Site 10
S89
A
L
V
S
E
A
D
S
E
S
R
F
Q
R
L
Site 11
S91
V
S
E
A
D
S
E
S
R
F
Q
R
L
S
S
Site 12
S97
E
S
R
F
Q
R
L
S
S
T
S
S
S
G
Q
Site 13
S98
S
R
F
Q
R
L
S
S
T
S
S
S
G
Q
Q
Site 14
T99
R
F
Q
R
L
S
S
T
S
S
S
G
Q
Q
D
Site 15
S100
F
Q
R
L
S
S
T
S
S
S
G
Q
Q
D
F
Site 16
S101
Q
R
L
S
S
T
S
S
S
G
Q
Q
D
F
E
Site 17
S102
R
L
S
S
T
S
S
S
G
Q
Q
D
F
E
N
Site 18
Y139
C
G
E
D
A
I
H
Y
L
S
F
Q
R
H
I
Site 19
Y176
D
L
L
D
K
D
P
Y
S
F
G
R
T
T
I
Site 20
S177
L
L
D
K
D
P
Y
S
F
G
R
T
T
I
A
Site 21
T181
D
P
Y
S
F
G
R
T
T
I
A
N
L
Q
T
Site 22
T182
P
Y
S
F
G
R
T
T
I
A
N
L
Q
T
D
Site 23
T215
V
G
F
M
R
H
H
T
Q
S
I
K
Y
K
E
Site 24
T229
E
E
N
L
V
R
R
T
L
F
I
T
G
L
P
Site 25
T233
V
R
R
T
L
F
I
T
G
L
P
R
D
A
R
Site 26
T243
P
R
D
A
R
K
E
T
V
E
S
H
F
R
D
Site 27
S246
A
R
K
E
T
V
E
S
H
F
R
D
A
Y
P
Site 28
Y252
E
S
H
F
R
D
A
Y
P
T
C
E
V
V
D
Site 29
Y271
Y
N
V
A
K
L
I
Y
L
C
K
E
K
K
K
Site 30
T279
L
C
K
E
K
K
K
T
E
K
S
L
T
Y
Y
Site 31
S282
E
K
K
K
T
E
K
S
L
T
Y
Y
T
N
L
Site 32
T284
K
K
T
E
K
S
L
T
Y
Y
T
N
L
Q
V
Site 33
Y286
T
E
K
S
L
T
Y
Y
T
N
L
Q
V
K
T
Site 34
T293
Y
T
N
L
Q
V
K
T
G
Q
R
T
L
I
N
Site 35
Y323
E
W
E
D
A
I
S
Y
Y
T
R
M
K
D
R
Site 36
Y324
W
E
D
A
I
S
Y
Y
T
R
M
K
D
R
L
Site 37
T336
D
R
L
L
E
R
I
T
E
E
E
R
H
V
Q
Site 38
Y362
Q
E
K
S
M
A
T
Y
I
L
K
D
F
N
A
Site 39
S384
C
K
G
E
P
Q
P
S
S
H
S
R
E
L
Y
Site 40
S385
K
G
E
P
Q
P
S
S
H
S
R
E
L
Y
T
Site 41
S387
E
P
Q
P
S
S
H
S
R
E
L
Y
T
S
K
Site 42
Y391
S
S
H
S
R
E
L
Y
T
S
K
W
T
V
T
Site 43
T398
Y
T
S
K
W
T
V
T
F
A
A
D
P
E
D
Site 44
T487
P
S
I
V
Y
Y
S
T
L
L
E
S
H
W
T
Site 45
S491
Y
Y
S
T
L
L
E
S
H
W
T
K
S
G
E
Site 46
T494
T
L
L
E
S
H
W
T
K
S
G
E
N
Q
I
Site 47
T536
F
R
W
L
F
D
K
T
S
S
E
A
S
I
R
Site 48
S537
R
W
L
F
D
K
T
S
S
E
A
S
I
R
L
Site 49
S541
D
K
T
S
S
E
A
S
I
R
L
E
C
V
F
Site 50
Y605
K
Q
N
Q
A
F
Q
Y
E
F
G
A
M
Y
A
Site 51
Y651
M
V
D
R
H
N
L
Y
F
V
Y
L
P
A
K
Site 52
Y654
R
H
N
L
Y
F
V
Y
L
P
A
K
L
E
K
Site 53
S724
F
G
C
F
K
H
L
S
P
L
N
Y
K
T
E
Site 54
Y728
K
H
L
S
P
L
N
Y
K
T
E
E
P
A
S
Site 55
T730
L
S
P
L
N
Y
K
T
E
E
P
A
S
D
K
Site 56
S735
Y
K
T
E
E
P
A
S
D
K
G
S
E
A
E
Site 57
S739
E
P
A
S
D
K
G
S
E
A
E
A
H
M
P
Site 58
Y752
M
P
P
P
F
T
P
Y
V
P
R
I
L
N
G
Site 59
S762
R
I
L
N
G
L
A
S
E
R
T
A
L
S
P
Site 60
S768
A
S
E
R
T
A
L
S
P
Q
Q
Q
Q
Q
Q
Site 61
Y777
Q
Q
Q
Q
Q
Q
T
Y
G
A
I
H
N
I
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation