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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LRIG2
Full Name:
Leucine-rich repeats and immunoglobulin-like domains protein 2
Alias:
Type:
Mass (Da):
118965
Number AA:
1047
UniProt ID:
O94898
International Prot ID:
IPI00478892
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0016021
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S295
M
L
Q
Q
L
Y
V
S
Q
N
A
I
E
R
I
Site 2
Y838
M
R
R
K
N
E
D
Y
S
I
T
N
T
E
E
Site 3
S839
R
R
K
N
E
D
Y
S
I
T
N
T
E
E
L
Site 4
T843
E
D
Y
S
I
T
N
T
E
E
L
N
L
P
A
Site 5
S854
N
L
P
A
D
I
P
S
Y
L
S
S
Q
G
T
Site 6
Y855
L
P
A
D
I
P
S
Y
L
S
S
Q
G
T
L
Site 7
S857
A
D
I
P
S
Y
L
S
S
Q
G
T
L
S
E
Site 8
S858
D
I
P
S
Y
L
S
S
Q
G
T
L
S
E
P
Site 9
T861
S
Y
L
S
S
Q
G
T
L
S
E
P
Q
E
G
Site 10
S863
L
S
S
Q
G
T
L
S
E
P
Q
E
G
Y
S
Site 11
S870
S
E
P
Q
E
G
Y
S
N
S
E
A
G
S
H
Site 12
S872
P
Q
E
G
Y
S
N
S
E
A
G
S
H
Q
Q
Site 13
S876
Y
S
N
S
E
A
G
S
H
Q
Q
L
M
P
P
Site 14
Y887
L
M
P
P
A
N
G
Y
I
H
K
G
T
D
G
Site 15
T892
N
G
Y
I
H
K
G
T
D
G
G
T
G
T
R
Site 16
Y906
R
V
I
C
S
D
C
Y
D
N
A
N
I
Y
S
Site 17
Y912
C
Y
D
N
A
N
I
Y
S
R
T
R
E
Y
C
Site 18
Y918
I
Y
S
R
T
R
E
Y
C
P
Y
T
Y
I
A
Site 19
Y921
R
T
R
E
Y
C
P
Y
T
Y
I
A
E
E
D
Site 20
Y923
R
E
Y
C
P
Y
T
Y
I
A
E
E
D
V
L
Site 21
T933
E
E
D
V
L
D
Q
T
L
S
S
L
M
V
Q
Site 22
Y946
V
Q
M
P
K
E
T
Y
L
V
H
P
P
Q
D
Site 23
T955
V
H
P
P
Q
D
T
T
A
L
E
S
L
I
P
Site 24
S959
Q
D
T
T
A
L
E
S
L
I
P
S
A
N
R
Site 25
S963
A
L
E
S
L
I
P
S
A
N
R
E
P
S
A
Site 26
S969
P
S
A
N
R
E
P
S
A
F
P
T
N
H
E
Site 27
T973
R
E
P
S
A
F
P
T
N
H
E
R
I
S
E
Site 28
S979
P
T
N
H
E
R
I
S
E
K
K
L
P
S
T
Site 29
S985
I
S
E
K
K
L
P
S
T
Q
M
S
G
E
T
Site 30
T986
S
E
K
K
L
P
S
T
Q
M
S
G
E
T
L
Site 31
S989
K
L
P
S
T
Q
M
S
G
E
T
L
Q
R
P
Site 32
S1012
G
L
P
H
P
P
F
S
Q
Q
P
V
H
E
S
Site 33
S1019
S
Q
Q
P
V
H
E
S
P
Q
L
H
Q
N
E
Site 34
S1036
A
G
R
E
P
D
C
S
A
S
S
M
S
C
H
Site 35
S1038
R
E
P
D
C
S
A
S
S
M
S
C
H
R
L
Site 36
S1039
E
P
D
C
S
A
S
S
M
S
C
H
R
L
Q
Site 37
S1041
D
C
S
A
S
S
M
S
C
H
R
L
Q
D
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation