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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ENDOD1
Full Name:
Endonuclease domain-containing 1 protein
Alias:
EC 3.1.30.-; ENDD1; Endonuclease domain-containing 1
Type:
Uncharacterized protein
Mass (Da):
55017
Number AA:
500
UniProt ID:
O94919
International Prot ID:
IPI00001952
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
Uniprot
OncoNet
Molecular Function:
GO:0004519
GO:0046872
GO:0003676
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y39
G
E
C
D
K
F
F
Y
A
G
T
P
P
A
G
Site 2
S51
P
A
G
L
A
A
D
S
H
V
K
I
C
Q
R
Site 3
T67
E
G
A
E
R
F
A
T
L
Y
S
T
R
D
R
Site 4
Y69
A
E
R
F
A
T
L
Y
S
T
R
D
R
I
P
Site 5
S70
E
R
F
A
T
L
Y
S
T
R
D
R
I
P
V
Site 6
T71
R
F
A
T
L
Y
S
T
R
D
R
I
P
V
Y
Site 7
Y78
T
R
D
R
I
P
V
Y
S
A
F
R
A
P
R
Site 8
S79
R
D
R
I
P
V
Y
S
A
F
R
A
P
R
P
Site 9
S106
P
Q
I
D
D
P
N
S
N
L
E
E
A
I
N
Site 10
S120
N
E
A
E
A
I
T
S
V
N
S
L
G
S
K
Site 11
S123
E
A
I
T
S
V
N
S
L
G
S
K
Q
A
L
Site 12
Y134
K
Q
A
L
N
T
D
Y
L
D
S
D
Y
Q
R
Site 13
S137
L
N
T
D
Y
L
D
S
D
Y
Q
R
G
Q
L
Site 14
Y139
T
D
Y
L
D
S
D
Y
Q
R
G
Q
L
Y
P
Site 15
Y145
D
Y
Q
R
G
Q
L
Y
P
F
S
L
S
S
D
Site 16
S148
R
G
Q
L
Y
P
F
S
L
S
S
D
V
Q
V
Site 17
S163
A
T
F
T
L
T
N
S
A
P
M
T
Q
S
F
Site 18
T167
L
T
N
S
A
P
M
T
Q
S
F
Q
E
R
W
Site 19
Y175
Q
S
F
Q
E
R
W
Y
V
N
L
H
S
L
M
Site 20
T187
S
L
M
D
R
A
L
T
P
Q
C
G
S
G
E
Site 21
T200
G
E
D
L
Y
I
L
T
G
T
V
P
S
D
Y
Site 22
S205
I
L
T
G
T
V
P
S
D
Y
R
V
K
D
K
Site 23
Y207
T
G
T
V
P
S
D
Y
R
V
K
D
K
V
A
Site 24
S243
F
V
K
H
T
R
D
S
D
I
I
E
D
V
M
Site 25
T276
C
G
E
T
E
Q
D
T
E
K
M
K
K
I
L
Site 26
S298
D
E
E
R
M
V
Q
S
Q
K
S
S
S
P
L
Site 27
S301
R
M
V
Q
S
Q
K
S
S
S
P
L
S
S
T
Site 28
S302
M
V
Q
S
Q
K
S
S
S
P
L
S
S
T
R
Site 29
S303
V
Q
S
Q
K
S
S
S
P
L
S
S
T
R
S
Site 30
S306
Q
K
S
S
S
P
L
S
S
T
R
S
K
R
S
Site 31
S307
K
S
S
S
P
L
S
S
T
R
S
K
R
S
T
Site 32
T308
S
S
S
P
L
S
S
T
R
S
K
R
S
T
L
Site 33
S310
S
P
L
S
S
T
R
S
K
R
S
T
L
L
P
Site 34
S313
S
S
T
R
S
K
R
S
T
L
L
P
P
E
A
Site 35
T314
S
T
R
S
K
R
S
T
L
L
P
P
E
A
S
Site 36
S321
T
L
L
P
P
E
A
S
E
G
S
S
S
F
L
Site 37
S325
P
E
A
S
E
G
S
S
S
F
L
G
K
L
M
Site 38
S326
E
A
S
E
G
S
S
S
F
L
G
K
L
M
G
Site 39
Y490
S
V
C
K
R
I
G
Y
K
V
T
F
D
N
S
Site 40
T493
K
R
I
G
Y
K
V
T
F
D
N
S
G
E
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation