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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
abLIM3
Full Name:
Actin-binding LIM protein 3
Alias:
ABLIM3, KIAA0843; ABLM3; Actin binding LIM protein family, member 3; Actin-binding LIM protein family member 3; ALM3; HMFN1661; KIAA0843
Type:
Cytoskeletal protein; Actin binding protein
Mass (Da):
77802
Number AA:
683
UniProt ID:
O94929
International Prot ID:
IPI00185892
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0003779
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0007010
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y12
I
P
Y
Q
Q
N
P
Y
N
P
R
G
S
S
N
Site 2
S18
P
Y
N
P
R
G
S
S
N
V
I
Q
C
Y
R
Site 3
Y24
S
S
N
V
I
Q
C
Y
R
C
G
D
T
C
K
Site 4
Y68
F
F
F
K
N
Q
E
Y
I
C
T
Q
D
Y
Q
Site 5
Y74
E
Y
I
C
T
Q
D
Y
Q
Q
L
Y
G
T
R
Site 6
Y78
T
Q
D
Y
Q
Q
L
Y
G
T
R
C
D
S
C
Site 7
S109
H
P
K
C
F
V
C
S
L
C
R
K
P
F
P
Site 8
S134
E
C
V
C
Q
T
C
S
Q
S
M
A
S
S
K
Site 9
S136
V
C
Q
T
C
S
Q
S
M
A
S
S
K
P
I
Site 10
S140
C
S
Q
S
M
A
S
S
K
P
I
K
I
R
G
Site 11
S149
P
I
K
I
R
G
P
S
H
C
A
G
C
K
E
Site 12
T186
Q
T
C
S
V
I
L
T
G
E
Y
I
S
K
D
Site 13
Y202
V
P
Y
C
E
S
D
Y
H
A
Q
F
G
I
K
Site 14
Y216
K
C
E
T
C
D
R
Y
I
S
G
R
V
L
E
Site 15
S218
E
T
C
D
R
Y
I
S
G
R
V
L
E
A
G
Site 16
Y250
F
T
E
G
E
E
M
Y
L
T
G
S
E
V
W
Site 17
T252
E
G
E
E
M
Y
L
T
G
S
E
V
W
H
P
Site 18
T276
K
K
L
K
H
R
R
T
S
E
T
S
I
S
P
Site 19
S277
K
L
K
H
R
R
T
S
E
T
S
I
S
P
P
Site 20
T279
K
H
R
R
T
S
E
T
S
I
S
P
P
G
S
Site 21
S280
H
R
R
T
S
E
T
S
I
S
P
P
G
S
S
Site 22
S282
R
T
S
E
T
S
I
S
P
P
G
S
S
I
G
Site 23
S286
T
S
I
S
P
P
G
S
S
I
G
S
P
N
R
Site 24
S287
S
I
S
P
P
G
S
S
I
G
S
P
N
R
V
Site 25
S290
P
P
G
S
S
I
G
S
P
N
R
V
I
C
A
Site 26
Y306
V
D
N
E
I
L
N
Y
K
D
L
A
A
L
P
Site 27
S317
A
A
L
P
K
V
K
S
I
Y
E
V
Q
R
P
Site 28
Y319
L
P
K
V
K
S
I
Y
E
V
Q
R
P
D
L
Site 29
S328
V
Q
R
P
D
L
I
S
Y
E
P
H
S
R
Y
Site 30
Y329
Q
R
P
D
L
I
S
Y
E
P
H
S
R
Y
M
Site 31
S333
L
I
S
Y
E
P
H
S
R
Y
M
S
D
E
M
Site 32
Y335
S
Y
E
P
H
S
R
Y
M
S
D
E
M
L
E
Site 33
S337
E
P
H
S
R
Y
M
S
D
E
M
L
E
R
C
Site 34
Y346
E
M
L
E
R
C
G
Y
G
E
S
L
G
T
L
Site 35
S349
E
R
C
G
Y
G
E
S
L
G
T
L
S
P
Y
Site 36
T352
G
Y
G
E
S
L
G
T
L
S
P
Y
S
Q
D
Site 37
S354
G
E
S
L
G
T
L
S
P
Y
S
Q
D
I
Y
Site 38
Y356
S
L
G
T
L
S
P
Y
S
Q
D
I
Y
E
N
Site 39
S357
L
G
T
L
S
P
Y
S
Q
D
I
Y
E
N
L
Site 40
Y361
S
P
Y
S
Q
D
I
Y
E
N
L
D
L
R
Q
Site 41
S372
D
L
R
Q
R
R
A
S
S
P
G
Y
I
D
S
Site 42
S373
L
R
Q
R
R
A
S
S
P
G
Y
I
D
S
P
Site 43
Y376
R
R
A
S
S
P
G
Y
I
D
S
P
T
Y
S
Site 44
S379
S
S
P
G
Y
I
D
S
P
T
Y
S
R
Q
G
Site 45
T381
P
G
Y
I
D
S
P
T
Y
S
R
Q
G
M
S
Site 46
Y382
G
Y
I
D
S
P
T
Y
S
R
Q
G
M
S
P
Site 47
S383
Y
I
D
S
P
T
Y
S
R
Q
G
M
S
P
T
Site 48
S388
T
Y
S
R
Q
G
M
S
P
T
F
S
R
S
P
Site 49
T390
S
R
Q
G
M
S
P
T
F
S
R
S
P
H
H
Site 50
S392
Q
G
M
S
P
T
F
S
R
S
P
H
H
Y
Y
Site 51
S394
M
S
P
T
F
S
R
S
P
H
H
Y
Y
R
S
Site 52
Y398
F
S
R
S
P
H
H
Y
Y
R
S
G
P
E
S
Site 53
Y399
S
R
S
P
H
H
Y
Y
R
S
G
P
E
S
G
Site 54
S401
S
P
H
H
Y
Y
R
S
G
P
E
S
G
R
S
Site 55
S405
Y
Y
R
S
G
P
E
S
G
R
S
S
P
Y
H
Site 56
S408
S
G
P
E
S
G
R
S
S
P
Y
H
S
Q
L
Site 57
S409
G
P
E
S
G
R
S
S
P
Y
H
S
Q
L
D
Site 58
Y411
E
S
G
R
S
S
P
Y
H
S
Q
L
D
V
R
Site 59
S413
G
R
S
S
P
Y
H
S
Q
L
D
V
R
S
S
Site 60
S419
H
S
Q
L
D
V
R
S
S
T
P
T
S
Y
Q
Site 61
S420
S
Q
L
D
V
R
S
S
T
P
T
S
Y
Q
A
Site 62
T421
Q
L
D
V
R
S
S
T
P
T
S
Y
Q
A
P
Site 63
T423
D
V
R
S
S
T
P
T
S
Y
Q
A
P
K
H
Site 64
S424
V
R
S
S
T
P
T
S
Y
Q
A
P
K
H
F
Site 65
Y425
R
S
S
T
P
T
S
Y
Q
A
P
K
H
F
H
Site 66
Y441
P
A
G
D
S
N
I
Y
R
K
P
P
I
Y
K
Site 67
Y447
I
Y
R
K
P
P
I
Y
K
R
H
G
D
L
S
Site 68
S454
Y
K
R
H
G
D
L
S
T
A
T
K
S
K
T
Site 69
T455
K
R
H
G
D
L
S
T
A
T
K
S
K
T
S
Site 70
T457
H
G
D
L
S
T
A
T
K
S
K
T
S
E
D
Site 71
S459
D
L
S
T
A
T
K
S
K
T
S
E
D
I
S
Site 72
T461
S
T
A
T
K
S
K
T
S
E
D
I
S
Q
T
Site 73
S462
T
A
T
K
S
K
T
S
E
D
I
S
Q
T
S
Site 74
S466
S
K
T
S
E
D
I
S
Q
T
S
K
Y
S
P
Site 75
T468
T
S
E
D
I
S
Q
T
S
K
Y
S
P
I
Y
Site 76
S469
S
E
D
I
S
Q
T
S
K
Y
S
P
I
Y
S
Site 77
Y471
D
I
S
Q
T
S
K
Y
S
P
I
Y
S
P
D
Site 78
S472
I
S
Q
T
S
K
Y
S
P
I
Y
S
P
D
P
Site 79
Y475
T
S
K
Y
S
P
I
Y
S
P
D
P
Y
Y
A
Site 80
S476
S
K
Y
S
P
I
Y
S
P
D
P
Y
Y
A
S
Site 81
Y480
P
I
Y
S
P
D
P
Y
Y
A
S
E
S
E
Y
Site 82
Y481
I
Y
S
P
D
P
Y
Y
A
S
E
S
E
Y
W
Site 83
S483
S
P
D
P
Y
Y
A
S
E
S
E
Y
W
T
Y
Site 84
Y487
Y
Y
A
S
E
S
E
Y
W
T
Y
H
G
S
P
Site 85
T489
A
S
E
S
E
Y
W
T
Y
H
G
S
P
K
V
Site 86
Y490
S
E
S
E
Y
W
T
Y
H
G
S
P
K
V
P
Site 87
S493
E
Y
W
T
Y
H
G
S
P
K
V
P
R
A
R
Site 88
S503
V
P
R
A
R
R
F
S
S
G
G
E
E
D
D
Site 89
S504
P
R
A
R
R
F
S
S
G
G
E
E
D
D
F
Site 90
S514
E
E
D
D
F
D
R
S
M
H
K
L
Q
S
G
Site 91
S520
R
S
M
H
K
L
Q
S
G
I
G
R
L
I
L
Site 92
S535
K
E
E
M
K
A
R
S
S
S
Y
A
D
P
W
Site 93
S536
E
E
M
K
A
R
S
S
S
Y
A
D
P
W
T
Site 94
S537
E
M
K
A
R
S
S
S
Y
A
D
P
W
T
P
Site 95
Y538
M
K
A
R
S
S
S
Y
A
D
P
W
T
P
P
Site 96
T543
S
S
Y
A
D
P
W
T
P
P
R
S
S
T
S
Site 97
S547
D
P
W
T
P
P
R
S
S
T
S
S
R
E
A
Site 98
S548
P
W
T
P
P
R
S
S
T
S
S
R
E
A
L
Site 99
T549
W
T
P
P
R
S
S
T
S
S
R
E
A
L
H
Site 100
S550
T
P
P
R
S
S
T
S
S
R
E
A
L
H
T
Site 101
S551
P
P
R
S
S
T
S
S
R
E
A
L
H
T
A
Site 102
T557
S
S
R
E
A
L
H
T
A
G
Y
E
M
S
L
Site 103
Y560
E
A
L
H
T
A
G
Y
E
M
S
L
N
G
S
Site 104
S563
H
T
A
G
Y
E
M
S
L
N
G
S
P
R
S
Site 105
S567
Y
E
M
S
L
N
G
S
P
R
S
H
Y
L
A
Site 106
S570
S
L
N
G
S
P
R
S
H
Y
L
A
D
S
D
Site 107
Y572
N
G
S
P
R
S
H
Y
L
A
D
S
D
P
L
Site 108
S576
R
S
H
Y
L
A
D
S
D
P
L
I
S
K
S
Site 109
S581
A
D
S
D
P
L
I
S
K
S
A
S
L
P
A
Site 110
S583
S
D
P
L
I
S
K
S
A
S
L
P
A
Y
R
Site 111
S585
P
L
I
S
K
S
A
S
L
P
A
Y
R
R
N
Site 112
Y589
K
S
A
S
L
P
A
Y
R
R
N
G
L
H
R
Site 113
T597
R
R
N
G
L
H
R
T
P
S
A
D
L
F
H
Site 114
S599
N
G
L
H
R
T
P
S
A
D
L
F
H
Y
D
Site 115
Y605
P
S
A
D
L
F
H
Y
D
S
M
N
A
V
N
Site 116
Y618
V
N
W
G
M
R
E
Y
K
I
Y
P
Y
E
L
Site 117
T629
P
Y
E
L
L
L
V
T
T
R
G
R
N
R
L
Site 118
S650
T
R
L
E
R
H
L
S
Q
E
E
F
Y
Q
V
Site 119
Y655
H
L
S
Q
E
E
F
Y
Q
V
F
G
M
T
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation