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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
UBOX5
Full Name:
RING finger protein 37
Alias:
U-box domain-containing protein 5;Ubiquitin-conjugating enzyme 7-interacting protein 5
Type:
Mass (Da):
58966
Number AA:
541
UniProt ID:
O94941
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y24
N
K
I
S
A
D
G
Y
E
V
E
N
L
I
S
Site 2
T35
N
L
I
S
E
D
L
T
K
R
S
H
G
F
R
Site 3
S38
S
E
D
L
T
K
R
S
H
G
F
R
T
E
Y
Site 4
Y45
S
H
G
F
R
T
E
Y
F
I
K
P
P
V
Y
Site 5
Y84
N
V
T
G
L
E
M
Y
T
S
A
S
S
S
R
Site 6
T85
V
T
G
L
E
M
Y
T
S
A
S
S
S
R
V
Site 7
S86
T
G
L
E
M
Y
T
S
A
S
S
S
R
V
S
Site 8
S88
L
E
M
Y
T
S
A
S
S
S
R
V
S
W
N
Site 9
S89
E
M
Y
T
S
A
S
S
S
R
V
S
W
N
T
Site 10
S90
M
Y
T
S
A
S
S
S
R
V
S
W
N
T
P
Site 11
S93
S
A
S
S
S
R
V
S
W
N
T
P
Q
C
R
Site 12
T96
S
S
R
V
S
W
N
T
P
Q
C
R
T
L
G
Site 13
S108
T
L
G
P
A
E
P
S
V
P
D
K
E
A
F
Site 14
S127
K
V
L
L
K
N
Q
S
Q
V
V
F
S
H
R
Site 15
S132
N
Q
S
Q
V
V
F
S
H
R
G
F
K
A
R
Site 16
T200
V
W
G
Q
P
A
K
T
C
S
Q
E
V
I
D
Site 17
S202
G
Q
P
A
K
T
C
S
Q
E
V
I
D
S
I
Site 18
S242
D
P
G
D
Q
P
E
S
Q
Q
A
P
S
S
L
Site 19
S248
E
S
Q
Q
A
P
S
S
L
Q
K
L
A
E
I
Site 20
S287
S
G
K
V
I
D
Q
S
T
L
E
K
C
N
R
Site 21
T288
G
K
V
I
D
Q
S
T
L
E
K
C
N
R
S
Site 22
T298
K
C
N
R
S
E
A
T
W
G
R
V
P
S
D
Site 23
S304
A
T
W
G
R
V
P
S
D
P
F
T
G
V
A
Site 24
T308
R
V
P
S
D
P
F
T
G
V
A
F
T
P
H
Site 25
T313
P
F
T
G
V
A
F
T
P
H
S
Q
P
L
P
Site 26
S316
G
V
A
F
T
P
H
S
Q
P
L
P
H
P
S
Site 27
S323
S
Q
P
L
P
H
P
S
L
K
A
R
I
D
H
Site 28
S361
P
S
S
I
V
L
P
S
Q
K
R
K
I
E
Q
Site 29
S375
Q
A
E
H
V
P
D
S
N
F
G
V
N
A
S
Site 30
S382
S
N
F
G
V
N
A
S
C
F
S
A
T
S
P
Site 31
T395
S
P
L
V
L
P
T
T
S
E
H
T
A
K
K
Site 32
T406
T
A
K
K
M
K
A
T
N
E
P
S
L
T
H
Site 33
S410
M
K
A
T
N
E
P
S
L
T
H
M
D
C
S
Site 34
T412
A
T
N
E
P
S
L
T
H
M
D
C
S
T
G
Site 35
S417
S
L
T
H
M
D
C
S
T
G
P
L
S
H
E
Site 36
T418
L
T
H
M
D
C
S
T
G
P
L
S
H
E
Q
Site 37
S422
D
C
S
T
G
P
L
S
H
E
Q
K
L
S
Q
Site 38
S428
L
S
H
E
Q
K
L
S
Q
S
L
E
I
A
L
Site 39
S430
H
E
Q
K
L
S
Q
S
L
E
I
A
L
A
S
Site 40
S437
S
L
E
I
A
L
A
S
T
L
G
S
M
P
S
Site 41
S441
A
L
A
S
T
L
G
S
M
P
S
F
T
A
R
Site 42
S444
S
T
L
G
S
M
P
S
F
T
A
R
L
T
R
Site 43
T446
L
G
S
M
P
S
F
T
A
R
L
T
R
G
Q
Site 44
T450
P
S
F
T
A
R
L
T
R
G
Q
L
Q
H
L
Site 45
S462
Q
H
L
G
T
R
G
S
N
T
S
W
R
P
G
Site 46
T464
L
G
T
R
G
S
N
T
S
W
R
P
G
T
G
Site 47
S465
G
T
R
G
S
N
T
S
W
R
P
G
T
G
S
Site 48
T470
N
T
S
W
R
P
G
T
G
S
E
Q
P
G
S
Site 49
S472
S
W
R
P
G
T
G
S
E
Q
P
G
S
I
L
Site 50
S477
T
G
S
E
Q
P
G
S
I
L
G
P
E
C
A
Site 51
S491
A
S
C
K
R
V
F
S
P
Y
F
K
K
E
P
Site 52
Y493
C
K
R
V
F
S
P
Y
F
K
K
E
P
V
Y
Site 53
Y500
Y
F
K
K
E
P
V
Y
Q
L
P
C
G
H
L
Site 54
S519
C
L
G
E
K
Q
R
S
L
P
M
T
C
T
A
Site 55
T523
K
Q
R
S
L
P
M
T
C
T
A
C
Q
R
P
Site 56
T525
R
S
L
P
M
T
C
T
A
C
Q
R
P
V
A
Site 57
S533
A
C
Q
R
P
V
A
S
Q
D
V
L
R
V
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation