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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FBXO21
Full Name:
F-box only protein 21
Alias:
Type:
Mass (Da):
72270
Number AA:
628
UniProt ID:
O94952
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S56
A
A
D
I
G
R
V
S
S
T
C
R
R
L
R
Site 2
S57
A
D
I
G
R
V
S
S
T
C
R
R
L
R
E
Site 3
T58
D
I
G
R
V
S
S
T
C
R
R
L
R
E
L
Site 4
S68
R
L
R
E
L
C
Q
S
S
G
K
V
W
K
E
Site 5
S83
Q
F
R
V
R
W
P
S
L
M
K
H
Y
S
P
Site 6
Y93
K
H
Y
S
P
T
D
Y
V
N
W
L
E
E
Y
Site 7
S116
E
A
R
K
I
V
A
S
F
S
K
R
F
F
S
Site 8
S118
R
K
I
V
A
S
F
S
K
R
F
F
S
E
H
Site 9
S123
S
F
S
K
R
F
F
S
E
H
V
P
C
N
G
Site 10
S132
H
V
P
C
N
G
F
S
D
I
E
N
L
E
G
Site 11
Y164
R
K
A
L
T
W
K
Y
Y
A
K
K
I
L
Y
Site 12
Y165
K
A
L
T
W
K
Y
Y
A
K
K
I
L
Y
Y
Site 13
Y171
Y
Y
A
K
K
I
L
Y
Y
L
R
Q
Q
K
I
Site 14
Y172
Y
A
K
K
I
L
Y
Y
L
R
Q
Q
K
I
L
Site 15
Y192
F
L
Q
Q
P
D
D
Y
E
S
Y
L
E
G
A
Site 16
Y195
Q
P
D
D
Y
E
S
Y
L
E
G
A
V
Y
I
Site 17
Y201
S
Y
L
E
G
A
V
Y
I
D
Q
Y
C
N
P
Site 18
S210
D
Q
Y
C
N
P
L
S
D
I
S
L
K
D
I
Site 19
S213
C
N
P
L
S
D
I
S
L
K
D
I
Q
A
Q
Site 20
S237
K
T
L
R
G
I
N
S
R
H
P
S
L
A
F
Site 21
S241
G
I
N
S
R
H
P
S
L
A
F
K
A
G
E
Site 22
Y267
Q
V
L
D
A
M
N
Y
V
L
Y
D
Q
L
K
Site 23
Y270
D
A
M
N
Y
V
L
Y
D
Q
L
K
F
K
G
Site 24
Y282
F
K
G
N
R
M
D
Y
Y
N
A
L
N
L
Y
Site 25
Y283
K
G
N
R
M
D
Y
Y
N
A
L
N
L
Y
M
Site 26
T359
F
G
K
G
K
Q
L
T
V
K
E
C
E
Y
L
Site 27
Y365
L
T
V
K
E
C
E
Y
L
I
G
Q
H
V
T
Site 28
Y376
Q
H
V
T
A
A
L
Y
G
V
V
N
V
K
K
Site 29
S394
R
M
V
G
N
L
L
S
L
G
K
R
E
G
I
Site 30
S404
K
R
E
G
I
D
Q
S
Y
Q
L
L
R
D
S
Site 31
Y405
R
E
G
I
D
Q
S
Y
Q
L
L
R
D
S
L
Site 32
Y415
L
R
D
S
L
D
L
Y
L
A
M
Y
P
D
Q
Site 33
T459
D
I
L
Q
H
I
Q
T
L
D
P
G
Q
H
G
Site 34
Y470
G
Q
H
G
A
V
G
Y
L
V
Q
H
T
L
E
Site 35
S494
G
V
E
V
K
L
R
S
D
E
K
H
R
D
V
Site 36
Y503
E
K
H
R
D
V
C
Y
S
I
G
L
I
M
K
Site 37
Y514
L
I
M
K
H
K
R
Y
G
Y
N
C
V
I
Y
Site 38
Y551
H
G
H
H
Q
P
F
Y
N
V
L
V
E
D
G
Site 39
S559
N
V
L
V
E
D
G
S
C
R
Y
A
A
Q
E
Site 40
Y570
A
A
Q
E
N
L
E
Y
N
V
E
P
Q
E
I
Site 41
Y585
S
H
P
D
V
G
R
Y
F
S
E
F
T
G
T
Site 42
S587
P
D
V
G
R
Y
F
S
E
F
T
G
T
H
Y
Site 43
T592
Y
F
S
E
F
T
G
T
H
Y
I
P
N
A
E
Site 44
Y594
S
E
F
T
G
T
H
Y
I
P
N
A
E
L
E
Site 45
Y604
N
A
E
L
E
I
R
Y
P
E
D
L
E
F
V
Site 46
Y612
P
E
D
L
E
F
V
Y
E
T
V
Q
N
I
Y
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation