PhosphoNET

           
Protein Info 
   
Short Name:  USP19
Full Name:  Ubiquitin carboxyl-terminal hydrolase 19
Alias:  Deubiquitinating enzyme 19; KIAA0891; UB19; Ubiquitin specific peptidase 19; Ubiquitin thioesterase 19; Ubiquitin thiolesterase 19; Ubiquitin-specific processing protease 19; UBP19; Zinc finger MYND domain containing 9; ZMYND9
Type:  Ubiquitin conjugating system; Protease; EC 3.1.2.15
Mass (Da):  145651
Number AA:  1318
UniProt ID:  O94966
International Prot ID:  IPI00016589
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:  GO:0008234  GO:0004221  GO:0008270 PhosphoSite+ KinaseNET
Biological Process:  GO:0043161     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S6__MSGGASATGPRRG
Site 2T20GPPGLEDTTSKKKQK
Site 3T21PPGLEDTTSKKKQKD
Site 4S22PGLEDTTSKKKQKDR
Site 5S34KDRANQESKDGDPRK
Site 6T43DGDPRKETGSRYVAQ
Site 7S45DPRKETGSRYVAQAG
Site 8Y47RKETGSRYVAQAGLE
Site 9S58AGLEPLASGDPSASA
Site 10S62PLASGDPSASASHAA
Site 11S64ASGDPSASASHAAGI
Site 12S66GDPSASASHAAGITG
Site 13S74HAAGITGSRHRTRLF
Site 14T78ITGSRHRTRLFFPSS
Site 15S84RTRLFFPSSSGSAST
Site 16S85TRLFFPSSSGSASTP
Site 17S86RLFFPSSSGSASTPQ
Site 18S88FFPSSSGSASTPQEE
Site 19S90PSSSGSASTPQEEQT
Site 20T91SSSGSASTPQEEQTK
Site 21T111DPHDLLATPTPELLL
Site 22Y167QQWGGVFYAEIKSSC
Site 23S173FYAEIKSSCAKVQTR
Site 24T179SSCAKVQTRKGSLLH
Site 25S183KVQTRKGSLLHLTLP
Site 26T188KGSLLHLTLPKKVPM
Site 27S244PPGNDPVSPAMVRSR
Site 28S250VSPAMVRSRNPGKDD
Site 29S289LAFVKNDSYEKGPDS
Site 30Y290AFVKNDSYEKGPDSV
Site 31S296SYEKGPDSVVVHVYV
Site 32T310VKEICRDTSRVLFRE
Site 33S311KEICRDTSRVLFREQ
Site 34T321LFREQDFTLIFQTRD
Site 35S377ICLRKRQSQRWGGLE
Site 36T402VAVPTGPTPLDSTPP
Site 37S406TGPTPLDSTPPGGAP
Site 38T407GPTPLDSTPPGGAPH
Site 39T417GGAPHPLTGQEEARA
Site 40S430RAVEKDKSKARSEDT
Site 41S434KDKSKARSEDTGLDS
Site 42T437SKARSEDTGLDSVAT
Site 43S441SEDTGLDSVATRTPM
Site 44T444TGLDSVATRTPMEHV
Site 45T446LDSVATRTPMEHVTP
Site 46T452RTPMEHVTPKPETHL
Site 47T457HVTPKPETHLASPKP
Site 48S461KPETHLASPKPTCMV
Site 49T465HLASPKPTCMVPPMP
Site 50S474MVPPMPHSPVSGDSV
Site 51S477PMPHSPVSGDSVEEE
Site 52S480HSPVSGDSVEEEEEE
Site 53S514FMNSVIQSLSNTREL
Site 54S516NSVIQSLSNTRELRD
Site 55T518VIQSLSNTRELRDFF
Site 56Y536SFEAEINYNNPLGTG
Site 57T613RIQNKPYTETVDSDG
Site 58T615QNKPYTETVDSDGRP
Site 59S618PYTETVDSDGRPDEV
Site 60S640RHKMRNDSFIVDLFQ
Site 61Y650VDLFQGQYKSKLVCP
Site 62Y687QKVLPVFYFAREPHS
Site 63S694YFAREPHSKPIKFLV
Site 64S702KPIKFLVSVSKENST
Site 65S704IKFLVSVSKENSTAS
Site 66S708VSVSKENSTASEVLD
Site 67S711SKENSTASEVLDSLS
Site 68S718SEVLDSLSQSVHVKP
Site 69S720VLDSLSQSVHVKPEN
Site 70S745FHRVFLPSHSLDTVS
Site 71S747RVFLPSHSLDTVSPS
Site 72T750LPSHSLDTVSPSDTL
Site 73S752SHSLDTVSPSDTLLC
Site 74S785QQRPQVPSVPISKCA
Site 75S789QVPSVPISKCAACQR
Site 76S800ACQRKQQSEDEKLKR
Site 77Y812LKRCTRCYRVGYCNQ
Site 78Y816TRCYRVGYCNQLCQK
Site 79Y853VPASRLTYARLAQLL
Site 80S867LEGYARYSVSVFQPP
Site 81S869GYARYSVSVFQPPFQ
Site 82S884PGRMALESQSPGCTT
Site 83S886RMALESQSPGCTTLL
Site 84T890ESQSPGCTTLLSTGS
Site 85T891SQSPGCTTLLSTGSL
Site 86S897TTLLSTGSLEAGDSE
Site 87S903GSLEAGDSERDPIQP
Site 88T917PPELQLVTPMAEGDT
Site 89T924TPMAEGDTGLPRVWA
Site 90S940PDRGPVPSTSGISSE
Site 91T941DRGPVPSTSGISSEM
Site 92S942RGPVPSTSGISSEML
Site 93S946PSTSGISSEMLASGP
Site 94S958SGPIEVGSLPAGERV
Site 95S966LPAGERVSRPEAAVP
Site 96Y975PEAAVPGYQHPSEAM
Site 97T986SEAMNAHTPQFFIYK
Site 98Y992HTPQFFIYKIDSSNR
Site 99S996FFIYKIDSSNREQRL
Site 100S997FIYKIDSSNREQRLE
Site 101T1009RLEDKGDTPLELGDD
Site 102S1048ECAEDPGSAGEAARA
Site 103Y1080LAPEEAWYCPQCKQH
Site 104S1091CKQHREASKQLLLWR
Site 105S1111IVQLKRFSFRSFIWR
Site 106S1114LKRFSFRSFIWRDKI
Site 107S1135PVRNLDLSKFCIGQK
Site 108Y1149KEEQLPSYDLYAVIN
Site 109Y1152QLPSYDLYAVINHYG
Site 110S1177ARLPNDRSSQRSDVG
Site 111S1178RLPNDRSSQRSDVGW
Site 112S1181NDRSSQRSDVGWRLF
Site 113S1191GWRLFDDSTVTTVDE
Site 114T1192WRLFDDSTVTTVDES
Site 115T1195FDDSTVTTVDESQVV
Site 116S1199TVTTVDESQVVTRYA
Site 117Y1205ESQVVTRYAYVLFYR
Site 118Y1207QVVTRYAYVLFYRRR
Site 119Y1211RYAYVLFYRRRNSPV
Site 120S1216LFYRRRNSPVERPPR
Site 121S1227RPPRAGHSEHHPDLG
Site 122S1242PAAEAAASQASRIWQ
Site 123S1262EEPVPEGSGPLGPWG
Site 124T1282GPLPRGPTTPDEGCL
Site 125T1283PLPRGPTTPDEGCLR
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


2019 Kinexus Bioinformatics Corporation