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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SEC31L1
Full Name:
Protein transport protein Sec31A
Alias:
ABP125; ABP130; KIAA0905; SC31A; SEC31 A
Type:
Vesicle protein
Mass (Da):
133015
Number AA:
1220
UniProt ID:
O94979
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030127
GO:0005737
GO:0005783
Uniprot
OncoNet
Molecular Function:
GO:0048306
PhosphoSite+
KinaseNET
Biological Process:
GO:0006888
GO:0016044
GO:0015031
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
K
L
K
E
V
D
R
T
A
M
Q
A
W
S
P
Site 2
Y23
P
A
Q
N
H
P
I
Y
L
A
T
G
T
S
A
Site 3
T36
S
A
Q
Q
L
D
A
T
F
S
T
N
A
S
L
Site 4
S38
Q
Q
L
D
A
T
F
S
T
N
A
S
L
E
I
Site 5
S51
E
I
F
E
L
D
L
S
D
P
S
L
D
M
K
Site 6
S54
E
L
D
L
S
D
P
S
L
D
M
K
S
C
A
Site 7
S59
D
P
S
L
D
M
K
S
C
A
T
F
S
S
S
Site 8
T62
L
D
M
K
S
C
A
T
F
S
S
S
H
R
Y
Site 9
S64
M
K
S
C
A
T
F
S
S
S
H
R
Y
H
K
Site 10
S65
K
S
C
A
T
F
S
S
S
H
R
Y
H
K
L
Site 11
S66
S
C
A
T
F
S
S
S
H
R
Y
H
K
L
I
Site 12
Y69
T
F
S
S
S
H
R
Y
H
K
L
I
W
G
P
Site 13
Y77
H
K
L
I
W
G
P
Y
K
M
D
S
K
G
D
Site 14
S81
W
G
P
Y
K
M
D
S
K
G
D
V
S
G
V
Site 15
Y101
E
N
G
N
I
I
L
Y
D
P
S
K
I
I
A
Site 16
S140
F
Q
T
N
L
V
A
S
G
A
N
E
S
E
I
Site 17
Y148
G
A
N
E
S
E
I
Y
I
W
D
L
N
N
F
Site 18
T157
W
D
L
N
N
F
A
T
P
M
T
P
G
A
K
Site 19
T160
N
N
F
A
T
P
M
T
P
G
A
K
T
Q
P
Site 20
T165
P
M
T
P
G
A
K
T
Q
P
P
E
D
I
S
Site 21
S186
Q
V
Q
H
I
L
A
S
A
S
P
S
G
R
A
Site 22
S188
Q
H
I
L
A
S
A
S
P
S
G
R
A
T
V
Site 23
T194
A
S
P
S
G
R
A
T
V
W
D
L
R
K
N
Site 24
S250
M
W
D
L
R
F
A
S
S
P
L
R
V
L
E
Site 25
S251
W
D
L
R
F
A
S
S
P
L
R
V
L
E
N
Site 26
S278
A
D
P
E
L
L
L
S
C
G
K
D
A
K
I
Site 27
Y297
P
N
T
G
E
V
L
Y
E
L
P
T
N
T
Q
Site 28
S320
P
R
N
P
A
V
L
S
A
A
S
F
D
G
R
Site 29
S332
D
G
R
I
S
V
Y
S
I
M
G
G
S
T
D
Site 30
S350
Q
K
Q
V
D
K
L
S
S
S
F
G
N
L
D
Site 31
S351
K
Q
V
D
K
L
S
S
S
F
G
N
L
D
P
Site 32
S352
Q
V
D
K
L
S
S
S
F
G
N
L
D
P
F
Site 33
T361
G
N
L
D
P
F
G
T
G
Q
P
L
P
P
L
Site 34
T406
S
F
G
G
K
L
V
T
F
E
N
V
R
M
P
Site 35
S414
F
E
N
V
R
M
P
S
H
Q
G
A
E
Q
Q
Site 36
S430
Q
Q
H
H
V
F
I
S
Q
V
V
T
E
K
E
Site 37
S440
V
T
E
K
E
F
L
S
R
S
D
Q
L
Q
Q
Site 38
S465
C
Q
K
K
I
D
A
S
Q
T
E
F
E
K
N
Site 39
S485
K
V
N
F
E
D
D
S
R
G
K
Y
L
E
L
Site 40
Y489
E
D
D
S
R
G
K
Y
L
E
L
L
G
Y
R
Site 41
Y495
K
Y
L
E
L
L
G
Y
R
K
E
D
L
G
K
Site 42
S527
D
S
D
Q
V
A
Q
S
D
G
E
E
S
P
A
Site 43
S532
A
Q
S
D
G
E
E
S
P
A
A
E
E
Q
L
Site 44
S551
I
K
E
E
K
E
E
S
E
F
L
P
S
S
G
Site 45
S556
E
E
S
E
F
L
P
S
S
G
G
T
F
N
I
Site 46
S557
E
S
E
F
L
P
S
S
G
G
T
F
N
I
S
Site 47
S564
S
G
G
T
F
N
I
S
V
S
G
D
I
D
G
Site 48
Y617
L
A
R
T
Q
K
K
Y
F
A
K
S
Q
S
K
Site 49
S621
Q
K
K
Y
F
A
K
S
Q
S
K
I
T
R
L
Site 50
S682
R
L
E
N
E
G
D
S
L
L
Q
T
Q
A
C
Site 51
S712
W
T
K
A
Q
D
G
S
H
P
L
S
L
Q
D
Site 52
S716
Q
D
G
S
H
P
L
S
L
Q
D
L
I
E
K
Site 53
S799
E
P
V
A
G
H
E
S
P
K
I
P
Y
E
K
Site 54
Y804
H
E
S
P
K
I
P
Y
E
K
Q
Q
L
P
K
Site 55
Y831
P
R
V
Q
T
Q
Q
Y
Y
P
H
G
E
N
P
Site 56
Y832
R
V
Q
T
Q
Q
Y
Y
P
H
G
E
N
P
P
Site 57
S860
A
A
G
Q
L
P
T
S
P
G
H
M
H
T
Q
Site 58
T866
T
S
P
G
H
M
H
T
Q
V
P
P
Y
P
Q
Site 59
Y871
M
H
T
Q
V
P
P
Y
P
Q
P
Q
P
Y
Q
Site 60
Y877
P
Y
P
Q
P
Q
P
Y
Q
P
A
Q
P
Y
P
Site 61
Y883
P
Y
Q
P
A
Q
P
Y
P
F
G
T
G
G
S
Site 62
S890
Y
P
F
G
T
G
G
S
A
M
Y
R
P
Q
Q
Site 63
T903
Q
Q
P
V
A
P
P
T
S
N
A
Y
P
N
T
Site 64
S904
Q
P
V
A
P
P
T
S
N
A
Y
P
N
T
P
Site 65
Y907
A
P
P
T
S
N
A
Y
P
N
T
P
Y
I
S
Site 66
T910
T
S
N
A
Y
P
N
T
P
Y
I
S
S
A
S
Site 67
Y912
N
A
Y
P
N
T
P
Y
I
S
S
A
S
S
Y
Site 68
S914
Y
P
N
T
P
Y
I
S
S
A
S
S
Y
T
G
Site 69
S915
P
N
T
P
Y
I
S
S
A
S
S
Y
T
G
Q
Site 70
S918
P
Y
I
S
S
A
S
S
Y
T
G
Q
S
Q
L
Site 71
Y919
Y
I
S
S
A
S
S
Y
T
G
Q
S
Q
L
Y
Site 72
Y926
Y
T
G
Q
S
Q
L
Y
A
A
Q
H
Q
A
S
Site 73
S933
Y
A
A
Q
H
Q
A
S
S
P
T
S
S
P
A
Site 74
S934
A
A
Q
H
Q
A
S
S
P
T
S
S
P
A
T
Site 75
S937
H
Q
A
S
S
P
T
S
S
P
A
T
S
F
P
Site 76
S938
Q
A
S
S
P
T
S
S
P
A
T
S
F
P
P
Site 77
T941
S
P
T
S
S
P
A
T
S
F
P
P
P
P
S
Site 78
S942
P
T
S
S
P
A
T
S
F
P
P
P
P
S
S
Site 79
S948
T
S
F
P
P
P
P
S
S
G
A
S
F
Q
H
Site 80
S949
S
F
P
P
P
P
S
S
G
A
S
F
Q
H
G
Site 81
S952
P
P
P
S
S
G
A
S
F
Q
H
G
G
P
G
Site 82
S963
G
G
P
G
A
P
P
S
S
S
A
Y
A
L
P
Site 83
S964
G
P
G
A
P
P
S
S
S
A
Y
A
L
P
P
Site 84
S965
P
G
A
P
P
S
S
S
A
Y
A
L
P
P
G
Site 85
Y967
A
P
P
S
S
S
A
Y
A
L
P
P
G
T
T
Site 86
S981
T
G
T
L
P
A
A
S
E
L
P
A
S
Q
R
Site 87
S986
A
A
S
E
L
P
A
S
Q
R
T
G
P
Q
N
Site 88
T989
E
L
P
A
S
Q
R
T
G
P
Q
N
G
W
N
Site 89
S1033
N
P
L
G
D
P
Q
S
Q
M
L
Q
Q
Q
P
Site 90
S1041
Q
M
L
Q
Q
Q
P
S
A
P
V
P
L
S
S
Site 91
S1047
P
S
A
P
V
P
L
S
S
Q
S
S
F
P
Q
Site 92
S1048
S
A
P
V
P
L
S
S
Q
S
S
F
P
Q
P
Site 93
S1050
P
V
P
L
S
S
Q
S
S
F
P
Q
P
H
L
Site 94
S1051
V
P
L
S
S
Q
S
S
F
P
Q
P
H
L
P
Site 95
S1078
G
Q
T
G
M
P
P
S
F
S
K
P
N
I
E
Site 96
S1080
T
G
M
P
P
S
F
S
K
P
N
I
E
G
A
Site 97
T1095
P
G
A
P
I
G
N
T
F
Q
H
V
Q
S
L
Site 98
T1108
S
L
P
T
K
K
I
T
K
K
P
I
P
D
E
Site 99
T1121
D
E
H
L
I
L
K
T
T
F
E
D
L
I
Q
Site 100
T1122
E
H
L
I
L
K
T
T
F
E
D
L
I
Q
R
Site 101
S1132
D
L
I
Q
R
C
L
S
S
A
T
D
P
Q
T
Site 102
T1139
S
S
A
T
D
P
Q
T
K
R
K
L
D
D
A
Site 103
S1147
K
R
K
L
D
D
A
S
K
R
L
E
F
L
Y
Site 104
Y1154
S
K
R
L
E
F
L
Y
D
K
L
R
E
Q
T
Site 105
T1161
Y
D
K
L
R
E
Q
T
L
S
P
T
I
T
S
Site 106
S1163
K
L
R
E
Q
T
L
S
P
T
I
T
S
G
L
Site 107
T1165
R
E
Q
T
L
S
P
T
I
T
S
G
L
H
N
Site 108
Y1182
R
S
I
E
T
R
N
Y
S
E
G
L
T
M
H
Site 109
S1183
S
I
E
T
R
N
Y
S
E
G
L
T
M
H
T
Site 110
T1187
R
N
Y
S
E
G
L
T
M
H
T
H
I
V
S
Site 111
T1190
S
E
G
L
T
M
H
T
H
I
V
S
T
S
N
Site 112
S1194
T
M
H
T
H
I
V
S
T
S
N
F
S
E
T
Site 113
S1196
H
T
H
I
V
S
T
S
N
F
S
E
T
S
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation