PhosphoNET

           
Protein Info 
   
Short Name:  INMT
Full Name:  Indolethylamine N-methyltransferase
Alias:  Aromatic alkylamine N-methyltransferase
Type: 
Mass (Da):  28891
Number AA:  263
UniProt ID:  O95050
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y11GFTGGDEYQKHFLPR
Site 2Y20KHFLPRDYLATYYSF
Site 3T23LPRDYLATYYSFDGS
Site 4Y24PRDYLATYYSFDGSP
Site 5Y25RDYLATYYSFDGSPS
Site 6S26DYLATYYSFDGSPSP
Site 7S30TYYSFDGSPSPEAEM
Site 8S32YSFDGSPSPEAEMLK
Site 9T48NLECLHKTFGPGGLQ
Site 10T58PGGLQGDTLIDIGSG
Site 11T82CDSFQDITLSDFTDR
Site 12S84SFQDITLSDFTDRNR
Site 13T87DITLSDFTDRNREEL
Site 14Y105LKKEPGAYDWTPAVK
Site 15T108EPGAYDWTPAVKFAC
Site 16S121ACELEGNSGRWEEKE
Site 17S203TVTLRLPSYMVGKRE
Site 18Y204VTLRLPSYMVGKREF
Site 19S212MVGKREFSCVALEKE
Site 20S238DIEQLLHSPQSYSVT
Site 21S241QLLHSPQSYSVTNAA
Site 22Y242LLHSPQSYSVTNAAN
Site 23S243LHSPQSYSVTNAANN
Site 24T245SPQSYSVTNAANNGV
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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