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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CCNB2
Full Name:
G2/mitotic-specific cyclin-B2
Alias:
Cyclin B2; HsT17299
Type:
Protein-serine kinase regulatory subunit, activator, cyclin
Mass (Da):
45282
Number AA:
398
UniProt ID:
O95067
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
GO:0015630
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0051301
GO:0007067
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T8
M
A
L
L
R
R
P
T
V
S
S
D
L
E
N
Site 2
S10
L
L
R
R
P
T
V
S
S
D
L
E
N
I
D
Site 3
S11
L
R
R
P
T
V
S
S
D
L
E
N
I
D
T
Site 4
T18
S
D
L
E
N
I
D
T
G
V
N
S
K
V
K
Site 5
S22
N
I
D
T
G
V
N
S
K
V
K
S
H
V
T
Site 6
S26
G
V
N
S
K
V
K
S
H
V
T
I
R
R
T
Site 7
T29
S
K
V
K
S
H
V
T
I
R
R
T
V
L
E
Site 8
T33
S
H
V
T
I
R
R
T
V
L
E
E
I
G
N
Site 9
T43
E
E
I
G
N
R
V
T
T
R
A
A
Q
V
A
Site 10
T44
E
I
G
N
R
V
T
T
R
A
A
Q
V
A
K
Site 11
T75
V
N
K
Q
L
K
P
T
A
S
V
K
P
V
Q
Site 12
S77
K
Q
L
K
P
T
A
S
V
K
P
V
Q
M
E
Site 13
S92
K
L
A
P
K
G
P
S
P
T
P
E
D
V
S
Site 14
T94
A
P
K
G
P
S
P
T
P
E
D
V
S
M
K
Site 15
S99
S
P
T
P
E
D
V
S
M
K
E
E
N
L
C
Site 16
Y134
N
P
Q
L
C
S
D
Y
V
K
D
I
Y
Q
Y
Site 17
Y139
S
D
Y
V
K
D
I
Y
Q
Y
L
R
Q
L
E
Site 18
Y141
Y
V
K
D
I
Y
Q
Y
L
R
Q
L
E
V
L
Site 19
S150
R
Q
L
E
V
L
Q
S
I
N
P
H
F
L
D
Site 20
S178
D
W
L
V
Q
V
H
S
K
F
R
L
L
Q
E
Site 21
S204
F
L
Q
V
Q
P
V
S
R
K
K
L
Q
L
V
Site 22
S220
I
T
A
L
L
L
A
S
K
Y
E
E
M
F
S
Site 23
Y222
A
L
L
L
A
S
K
Y
E
E
M
F
S
P
N
Site 24
S227
S
K
Y
E
E
M
F
S
P
N
I
E
D
F
V
Site 25
Y235
P
N
I
E
D
F
V
Y
I
T
D
N
A
Y
T
Site 26
Y241
V
Y
I
T
D
N
A
Y
T
S
S
Q
I
R
E
Site 27
S244
T
D
N
A
Y
T
S
S
Q
I
R
E
M
E
T
Site 28
S274
L
H
F
L
R
R
A
S
K
A
G
E
V
D
V
Site 29
T285
E
V
D
V
E
Q
H
T
L
A
K
Y
L
M
E
Site 30
Y298
M
E
L
T
L
I
D
Y
D
M
V
H
Y
H
P
Site 31
S306
D
M
V
H
Y
H
P
S
K
V
A
A
A
A
S
Site 32
T359
V
K
V
N
E
N
L
T
K
F
I
A
I
K
N
Site 33
Y368
F
I
A
I
K
N
K
Y
A
S
S
K
L
L
K
Site 34
S371
I
K
N
K
Y
A
S
S
K
L
L
K
I
S
M
Site 35
S377
S
S
K
L
L
K
I
S
M
I
P
Q
L
N
S
Site 36
S392
K
A
V
K
D
L
A
S
P
L
I
G
R
S
_
Site 37
S398
A
S
P
L
I
G
R
S
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation