PhosphoNET

           
Protein Info 
   
Short Name:  HRBL
Full Name:  Arf-GAP domain and FG repeats-containing protein 2
Alias:  HIV-1 Rev binding protein-like; RABR; RAB-R; Rev/Rex activation domain b
Type:  Uncharacterized protein
Mass (Da):  48963
Number AA:  481
UniProt ID:  O95081
International Prot ID:  Isoform1 - IPI00418238
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:  GO:0008060  GO:0008270   PhosphoSite+ KinaseNET
Biological Process:  GO:0032312     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S16PGPGGGVSGGKAEAE
Site 2S40VRELGGCSQAGNRHC
Site 3S85NPPHRVKSISMTTFT
Site 4S87PHRVKSISMTTFTEP
Site 5T89RVKSISMTTFTEPEV
Site 6T119LGLFDARTSLVPDSR
Site 7S120GLFDARTSLVPDSRD
Site 8S125RTSLVPDSRDPQKVK
Site 9Y139KEFLQEKYEKKRWYV
Site 10Y145KYEKKRWYVPPDQVK
Site 11Y156DQVKGPTYTKGSAST
Site 12S160GPTYTKGSASTPVQG
Site 13S162TYTKGSASTPVQGSI
Site 14T163YTKGSASTPVQGSIP
Site 15S168ASTPVQGSIPEGKPL
Site 16T177PEGKPLRTLLGDPAP
Site 17S187GDPAPSLSVAASTSS
Site 18S191PSLSVAASTSSQPVS
Site 19S193LSVAASTSSQPVSQS
Site 20S194SVAASTSSQPVSQSH
Site 21S198STSSQPVSQSHARTS
Site 22S200SSQPVSQSHARTSQA
Site 23S205SQSHARTSQARSTQP
Site 24S209ARTSQARSTQPPPHS
Site 25T210RTSQARSTQPPPHSS
Site 26S216STQPPPHSSVKKAST
Site 27S217TQPPPHSSVKKASTD
Site 28T253FPAFGGQTPSQGGFA
Site 29S255AFGGQTPSQGGFANF
Site 30S266FANFDAFSSGPSSSV
Site 31S267ANFDAFSSGPSSSVF
Site 32S270DAFSSGPSSSVFGSL
Site 33S272FSSGPSSSVFGSLPP
Site 34S276PSSSVFGSLPPAGQA
Site 35S284LPPAGQASFQAQPTP
Site 36T290ASFQAQPTPAGSSQG
Site 37S294AQPTPAGSSQGTPFG
Site 38T298PAGSSQGTPFGATPL
Site 39T303QGTPFGATPLAPASQ
Site 40S309ATPLAPASQPNSLAD
Site 41S313APASQPNSLADVGSF
Site 42S346GQVPPLQSVTMGGGG
Site 43S355TMGGGGGSSTGLAFG
Site 44S375FTAPAAQSPLPSTNP
Site 45S379AAQSPLPSTNPFQPN
Site 46T380AQSPLPSTNPFQPNG
Site 47S397PGPGFGMSSAGPGFP
Site 48S398GPGFGMSSAGPGFPQ
Site 49T426APLFPPQTPLVQQQN
Site 50S435LVQQQNGSSFGDLGS
Site 51S436VQQQNGSSFGDLGSA
Site 52S442SSFGDLGSAKLGQRP
Site 53S451KLGQRPLSQPAGIST
Site 54S457LSQPAGISTNPFMTG
Site 55T463ISTNPFMTGPSSSPF
Site 56S466NPFMTGPSSSPFASK
Site 57S467PFMTGPSSSPFASKP
Site 58S468FMTGPSSSPFASKPP
Site 59S472PSSSPFASKPPTTNP
Site 60T476PFASKPPTTNPFL__
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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