PhosphoNET

           
Protein Info 
   
Short Name:  AKR7A3
Full Name:  Aflatoxin B1 aldehyde reductase member 3
Alias:  AFB1-AR 2
Type: 
Mass (Da):  37188
Number AA:  331
UniProt ID:  O95154
International Prot ID:  IPI00293721
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0005829  GO:0044424 Uniprot OncoNet
Molecular Function:  GO:0003824  GO:0004033  GO:0009055 PhosphoSite+ KinaseNET
Biological Process:  GO:0006081  GO:0008152  GO:0009987 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S6__MSRQLSRARPATV
Site 2T12LSRARPATVLGAMEM
Site 3T27GRRMDAPTSAAVTRA
Site 4S28RRMDAPTSAAVTRAF
Site 5T32APTSAAVTRAFLERG
Site 6T45RGHTEIDTAFVYSEG
Site 7Y49EIDTAFVYSEGQSET
Site 8S68LGLRLGGSDCRVKID
Site 9S85AIPLFGNSLKPDSLR
Site 10S90GNSLKPDSLRFQLET
Site 11T97SLRFQLETSLKRLQC
Site 12S98LRFQLETSLKRLQCP
Site 13Y111CPRVDLFYLHMPDHS
Site 14S118YLHMPDHSTPVEETL
Site 15T119LHMPDHSTPVEETLR
Site 16T124HSTPVEETLRACHQL
Site 17Y195RHFGLRFYAFNPLAG
Site 18Y209GGLLTGKYKYEDKNG
Site 19Y211LLTGKYKYEDKNGKQ
Site 20S262AYGASAPSMTSATLR
Site 21Y272SATLRWMYHHSQLQG
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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