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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
sciellin
Full Name:
Sciellin
Alias:
FLJ21667; MGC22531; SCEL
Type:
Adaptor/scaffold
Mass (Da):
77552
Number AA:
688
UniProt ID:
O95171
International Prot ID:
IPI00478672
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0001533
GO:0005737
GO:0016020
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0009790
GO:0030216
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
N
V
T
L
R
K
M
S
P
T
G
N
E
M
K
Site 2
T12
T
L
R
K
M
S
P
T
G
N
E
M
K
S
T
Site 3
S18
P
T
G
N
E
M
K
S
T
T
Q
G
T
T
R
Site 4
T19
T
G
N
E
M
K
S
T
T
Q
G
T
T
R
K
Site 5
T38
H
E
V
N
K
R
R
T
F
L
Q
D
N
S
W
Site 6
S44
R
T
F
L
Q
D
N
S
W
I
K
K
R
P
E
Site 7
Y58
E
E
E
K
D
E
N
Y
G
R
V
V
L
N
R
Site 8
S68
V
V
L
N
R
H
N
S
H
D
A
L
D
R
K
Site 9
T85
E
R
D
V
P
K
A
T
I
S
R
Y
S
S
D
Site 10
S87
D
V
P
K
A
T
I
S
R
Y
S
S
D
D
T
Site 11
S90
K
A
T
I
S
R
Y
S
S
D
D
T
L
D
R
Site 12
S91
A
T
I
S
R
Y
S
S
D
D
T
L
D
R
I
Site 13
T94
S
R
Y
S
S
D
D
T
L
D
R
I
S
D
R
Site 14
S99
D
D
T
L
D
R
I
S
D
R
N
D
A
A
K
Site 15
Y108
R
N
D
A
A
K
T
Y
K
A
N
T
L
D
N
Site 16
T118
N
T
L
D
N
Q
L
T
N
R
S
M
S
M
F
Site 17
S123
Q
L
T
N
R
S
M
S
M
F
R
S
L
E
V
Site 18
S127
R
S
M
S
M
F
R
S
L
E
V
T
K
L
Q
Site 19
T131
M
F
R
S
L
E
V
T
K
L
Q
P
G
G
S
Site 20
S138
T
K
L
Q
P
G
G
S
L
N
A
N
T
S
N
Site 21
S144
G
S
L
N
A
N
T
S
N
T
I
A
S
T
S
Site 22
T153
T
I
A
S
T
S
A
T
T
P
V
K
K
K
R
Site 23
T154
I
A
S
T
S
A
T
T
P
V
K
K
K
R
Q
Site 24
S162
P
V
K
K
K
R
Q
S
W
F
P
P
P
P
P
Site 25
Y171
F
P
P
P
P
P
G
Y
N
A
S
S
S
T
G
Site 26
S174
P
P
P
G
Y
N
A
S
S
S
T
G
T
R
R
Site 27
S175
P
P
G
Y
N
A
S
S
S
T
G
T
R
R
R
Site 28
S176
P
G
Y
N
A
S
S
S
T
G
T
R
R
R
E
Site 29
T179
N
A
S
S
S
T
G
T
R
R
R
E
P
G
V
Site 30
S195
P
P
I
P
P
K
P
S
S
P
V
S
S
P
N
Site 31
S196
P
I
P
P
K
P
S
S
P
V
S
S
P
N
Q
Site 32
S199
P
K
P
S
S
P
V
S
S
P
N
Q
L
R
Q
Site 33
S200
K
P
S
S
P
V
S
S
P
N
Q
L
R
Q
D
Site 34
Y219
H
P
P
K
P
G
V
Y
T
E
T
N
R
S
A
Site 35
T220
P
P
K
P
G
V
Y
T
E
T
N
R
S
A
E
Site 36
T222
K
P
G
V
Y
T
E
T
N
R
S
A
E
R
N
Site 37
S232
S
A
E
R
N
I
R
S
Q
D
L
D
N
I
V
Site 38
S244
N
I
V
K
V
A
T
S
L
Q
R
S
D
K
G
Site 39
S248
V
A
T
S
L
Q
R
S
D
K
G
E
E
L
D
Site 40
S263
N
L
I
K
M
N
K
S
L
N
R
N
Q
G
L
Site 41
S272
N
R
N
Q
G
L
D
S
L
F
R
A
N
P
K
Site 42
S289
E
R
E
K
R
A
K
S
L
E
S
L
I
Y
M
Site 43
S292
K
R
A
K
S
L
E
S
L
I
Y
M
S
T
R
Site 44
Y295
K
S
L
E
S
L
I
Y
M
S
T
R
T
D
K
Site 45
S297
L
E
S
L
I
Y
M
S
T
R
T
D
K
D
G
Site 46
T298
E
S
L
I
Y
M
S
T
R
T
D
K
D
G
K
Site 47
T300
L
I
Y
M
S
T
R
T
D
K
D
G
K
G
I
Site 48
S309
K
D
G
K
G
I
Q
S
L
G
S
P
I
K
V
Site 49
S312
K
G
I
Q
S
L
G
S
P
I
K
V
N
Q
R
Site 50
S332
K
G
R
Q
N
L
E
S
V
A
K
V
N
A
R
Site 51
T343
V
N
A
R
M
N
K
T
S
R
R
S
E
D
L
Site 52
S344
N
A
R
M
N
K
T
S
R
R
S
E
D
L
D
Site 53
S347
M
N
K
T
S
R
R
S
E
D
L
D
N
A
T
Site 54
T354
S
E
D
L
D
N
A
T
E
V
N
P
K
G
H
Site 55
T380
L
I
K
V
D
P
E
T
N
K
N
I
T
R
G
Site 56
S389
K
N
I
T
R
G
Q
S
L
D
N
L
I
K
V
Site 57
T397
L
D
N
L
I
K
V
T
P
E
V
K
R
S
N
Site 58
S403
V
T
P
E
V
K
R
S
N
Q
G
S
K
D
L
Site 59
S407
V
K
R
S
N
Q
G
S
K
D
L
N
N
F
I
Site 60
Y417
L
N
N
F
I
K
V
Y
P
G
T
E
K
S
T
Site 61
S423
V
Y
P
G
T
E
K
S
T
E
G
G
Q
S
L
Site 62
S429
K
S
T
E
G
G
Q
S
L
D
S
L
I
K
V
Site 63
S432
E
G
G
Q
S
L
D
S
L
I
K
V
T
P
E
Site 64
T437
L
D
S
L
I
K
V
T
P
E
R
N
R
T
N
Site 65
T443
V
T
P
E
R
N
R
T
N
Q
G
N
Q
D
L
Site 66
S459
N
L
I
K
V
I
P
S
A
N
K
S
S
E
Q
Site 67
S463
V
I
P
S
A
N
K
S
S
E
Q
G
L
D
E
Site 68
S475
L
D
E
H
I
N
V
S
P
K
A
V
K
N
T
Site 69
S524
A
V
I
R
N
N
Q
S
Q
D
L
D
N
L
I
Site 70
S536
N
L
I
K
V
K
P
S
A
L
R
N
T
N
R
Site 71
T541
K
P
S
A
L
R
N
T
N
R
D
Q
N
L
E
Site 72
S555
E
N
L
I
E
V
N
S
H
V
S
E
N
K
N
Site 73
S558
I
E
V
N
S
H
V
S
E
N
K
N
G
S
S
Site 74
S564
V
S
E
N
K
N
G
S
S
N
T
G
A
K
Q
Site 75
T567
N
K
N
G
S
S
N
T
G
A
K
Q
A
G
P
Site 76
T577
K
Q
A
G
P
Q
D
T
V
V
Y
T
R
T
Y
Site 77
Y580
G
P
Q
D
T
V
V
Y
T
R
T
Y
V
E
N
Site 78
Y584
T
V
V
Y
T
R
T
Y
V
E
N
S
K
S
P
Site 79
S590
T
Y
V
E
N
S
K
S
P
K
D
G
Y
Q
E
Site 80
Y595
S
K
S
P
K
D
G
Y
Q
E
N
I
S
G
K
Site 81
T606
I
S
G
K
Y
I
Q
T
V
Y
S
T
S
D
R
Site 82
Y608
G
K
Y
I
Q
T
V
Y
S
T
S
D
R
S
V
Site 83
S609
K
Y
I
Q
T
V
Y
S
T
S
D
R
S
V
I
Site 84
S611
I
Q
T
V
Y
S
T
S
D
R
S
V
I
E
R
Site 85
S614
V
Y
S
T
S
D
R
S
V
I
E
R
D
M
C
Site 86
Y623
I
E
R
D
M
C
T
Y
C
R
K
P
L
G
V
Site 87
S665
E
N
L
Q
A
G
D
S
I
W
I
Y
R
Q
T
Site 88
Y669
A
G
D
S
I
W
I
Y
R
Q
T
I
H
C
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation